Search Results - "Kawula, Thomas H."

Genetic requirements for Staphylococcus aureus nitric oxide resistance and virulence by Grosser, Melinda R, Paluscio, Elyse, Thurlow, Lance R, Dillon, Marcus M, Cooper, Vaughn S, Kawula, Thomas H, Richardson, Anthony R

“…Staphylococcus aureus exhibits many defenses against host innate immunity, including the ability to replicate in the presence of nitric oxide (NO·). S. aureus…”
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The antipsychotic olanzapine interacts with the gut microbiome to cause weight gain in mouse by Morgan, Andrew P, Crowley, James J, Nonneman, Randal J, Quackenbush, Corey R, Miller, Cheryl N, Ryan, Allison K, Bogue, Molly A, Paredes, Sur Herrera, Yourstone, Scott, Carroll, Ian M, Kawula, Thomas H, Bower, Maureen A, Sartor, R Balfour, Sullivan, Patrick F

“…The second-generation antipsychotic olanzapine is effective in reducing psychotic symptoms but can cause extreme weight gain in human patients. We investigated…”
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Francisella tularensis enters a double membraned compartment following cell-cell transfer by Steele, Shaun P, Chamberlain, Zach, Park, Jason, Kawula, Thomas H

“…Previously, we found that phagocytic cells ingest bacteria directly from the cytosol of infected cells without killing the initially infected cell (Steele et…”
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Trogocytosis-associated cell to cell spread of intracellular bacterial pathogens by Steele, Shaun, Radlinski, Lauren, Taft-Benz, Sharon, Brunton, Jason, Kawula, Thomas H

“…Macrophages are myeloid-derived phagocytic cells and one of the first immune cell types to respond to microbial infections. However, a number of bacterial…”
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Infected-Host-Cell Repertoire and Cellular Response in the Lung following Inhalation of Francisella tularensis Schu S4, LVS, or U112 by Hall, Joshua D, Woolard, Matthew D, Gunn, Bronwyn M, Craven, Robin R, Taft-Benz, Sharon, Frelinger, Jeffrey A, Kawula, Thomas H

“…Francisella tularensis causes systemic disease in humans and other mammals, with high morbidity and mortality associated with inhalation-acquired infection. F…”
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Defining the Metabolic Pathways and Host-Derived Carbon Substrates Required for Francisella tularensis Intracellular Growth by Radlinski, Lauren C, Brunton, Jason, Steele, Shaun, Taft-Benz, Sharon, Kawula, Thomas H

“…is a Gram-negative, facultative, intracellular bacterial pathogen and one of the most virulent organisms known. A hallmark of pathogenesis is the bacterium's…”
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Genome-Wide Identification of Francisella tularensis Virulence Determinants by Su, Jingliang, Yang, Jun, Zhao, Daimin, Kawula, Thomas H, Banas, Jeffrey A, Zhang, Jing-Ren

“…Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential for use as a biological weapon. The…”
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Respiratory Francisella tularensis Live Vaccine Strain Infection Induces Th17 Cells and Prostaglandin E₂, Which Inhibits Generation of Gamma Interferon-Positive T Cells by Woolard, Matthew D, Hensley, Lucinda L, Kawula, Thomas H, Frelinger, Jeffrey A

“…Two key routes of Francisella tularensis infection are through the skin and airway. We wished to understand how the route of inoculation influenced the primary…”
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TetR-Based Gene Regulation Systems for Francisella tularensis by LOVULLO, Eric D, MILLER, Cheryl N, PAVELKA, Martin S, KAWULA, Thomas H

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Francisella tularensis Replicates within Alveolar Type II Epithelial Cells In Vitro and In Vivo following Inhalation by Hall, Joshua D, Craven, Robin R, Fuller, James R, Pickles, Raymond J, Kawula, Thomas H

“…Francisella tularensis replicates in macrophages and dendritic cells, but interactions with other cell types have not been well described. F. tularensis LVS…”
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Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis by Huang, Max Tze-Han, Mortensen, Brittany L, Taxman, Debra J, Craven, Robin R, Taft-Benz, Sharon, Kijek, Todd M, Fuller, James R, Davis, Beckley K, Allen, Irving Coy, Brickey, Willie June, Gris, Denis, Wen, Haitao, Kawula, Thomas H, Ting, Jenny Pan-Yun

“…Francisella tularensis is a facultative intracellular pathogen and potential biothreat agent. Evasion of the immune response contributes to the extraordinary…”
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Infection with Francisella tularensis LVS clpB Leads to an Altered yet Protective Immune Response by Barrigan, Lydia M, Tuladhar, Shraddha, Brunton, Jason C, Woolard, Matthew D, Chen, Ching-ju, Saini, Divey, Frothingham, Richard, Sempowski, Gregory D, Kawula, Thomas H, Frelinger, Jeffrey A

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Francisella tularensis Invasion of Lung Epithelial Cells by Craven, Robin R, Hall, Joshua D, Fuller, James R, Taft-Benz, Sharon, Kawula, Thomas H

“…Francisella tularensis, a gram-negative facultative intracellular bacterial pathogen, causes disseminating infections in humans and other mammalian hosts…”
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RipA, a Cytoplasmic Membrane Protein Conserved among Francisella Species, Is Required for Intracellular Survival by Fuller, James R, Craven, Robin R, Hall, Joshua D, Kijek, Todd M, Taft-Benz, Sharon, Kawula, Thomas H

“…Francisella tularensis is a highly virulent bacterial pathogen that invades and replicates within numerous host cell types, including macrophages and…”
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PanG, a New Ketopantoate Reductase Involved in Pantothenate Synthesis by Miller, Cheryl N, LoVullo, Eric D, Kijek, Todd M, Fuller, James R, Brunton, Jason C, Steele, Shaun P, Taft-Benz, Sharon A, Richardson, Anthony R, Kawula, Thomas H

“…Pantothenate, commonly referred to as vitamin B5, is an essential molecule in the metabolism of living organisms and forms the core of coenzyme A. Unlike…”
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Francisella tularensis RipA Protein Topology and Identification of Functional Domains by Mortensen, Brittany L, Fuller, James R, Taft-Benz, Sharon, Collins, Edward J, Kawula, Thomas H

“…Francisella tularensis is a Gram-negative coccobacillus and is the etiological agent of the disease tularemia. Expression of the cytoplasmic membrane protein…”
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Environmental and intracellular regulation of Francisella tularensis ripA by Fuller, James R, Kijek, Todd M, Taft-Benz, Sharon, Kawula, Thomas H

“…Francisella tularensis is a highly virulent, facultative intracellular pathogen and the etiologic agent of the zoonotic disease Tularemia. RipA is a…”
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Effects of the Putative Transcriptional Regulator IclR on Francisella tularensis Pathogenesis by Mortensen, Brittany L, Fuller, James R, Taft-Benz, Sharon, Kijek, Todd M, Miller, Cheryl N, Huang, Max T.H, Kawula, Thomas H

“…Francisella tularensis is a highly virulent Gram-negative bacterium and is the etiological agent of the disease tularemia. IclR, a presumed transcriptional…”
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Use of Transposon-Transposase Complexes To Create Stable Insertion Mutant Strains of Francisella tularensis LVS by KAWULA, Thomas H, HALL, Joshua D, FULLER, James R, CRAVEN, Robin R

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of Francisella by Ledvina, Hannah E., Kelly, Katherine A., Eshraghi, Aria, Plemel, Rachael L., Peterson, S. Brook, Lee, Brian, Steele, Shaun, Adler, Marlen, Kawula, Thomas H., Merz, Alexey J., Skerrett, Shawn J., Celli, Jean, Mougous, Joseph D.

“…Many pathogenic intracellular bacteria manipulate the host phago-endosomal system to establish and maintain a permissive niche. The fate and identity of these…”
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