Search Results - "Kawish, Muhammad"
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Metronidazole conjugated magnetic nanoparticles loaded with amphotericin B exhibited potent effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype
Published in AMB Express (17-07-2020)“…Acanthamoeba castellanii can cause granulomatous amoebic encephalitis and Acanthamoeba keratitis. Currently, no single drug has been developed to effectively…”
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Enhancement in Oral Absorption of Ceftriaxone by Highly Functionalized Magnetic Iron Oxide Nanoparticles
Published in Pharmaceutics (28-05-2020)“…The present study aims at the development, characterization, biocompatibility investigation and oral bioavailability evaluation of ceftriaxone (CFT)-loaded…”
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Advancement in oral pharmacokinetics of an antibiotic Cefixime using amphiphilic 4-armed macrocyclic surfactant based niosomes
Published in Arabian journal of chemistry (01-08-2023)“…The four -armed long carbon chains supramolecular amphiphilic macrocycles are able to self-assemble into nanosized architectures called niosomes that have a…”
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Novel Plant-Based Metabolites as Disinfectants against Acanthamoeba castellanii
Published in Antibiotics (Basel) (14-02-2022)“…Due to global warming, coupled with global water shortages and the reliance of the public on household water tanks, especially in developing countries, it is…”
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Nanocarrier Drug Conjugates Exhibit Potent Anti- Naegleria fowleri and Anti- Balamuthia mandrillaris Properties
Published in Diseases (06-04-2023)“…Given the opportunity and access, pathogenic protists ( and ) can produce fatal infections involving the central nervous system. In the absence of effective…”
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Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris
Published in Antibiotics (Basel) (19-04-2022)“…and are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and…”
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Hesperidin-, Curcumin-, and Amphotericin B- Based Nano-Formulations as Potential Antibacterials
Published in Antibiotics (Basel) (20-05-2022)“…To combat the public health threat posed by multiple-drug-resistant (MDR) pathogens, new drugs with novel chemistry and modes of action are needed. In this…”
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Enhancing efficacy of existing antibacterials against selected multiple drug resistant bacteria using cinnamic acid-coated magnetic iron oxide and mesoporous silica nanoparticles
Published in Pathogens and global health (03-10-2022)“…Developing new antibacterial drugs by using traditional ways is insufficient to meet existing challenges; hence, new strategies in the field of antibacterial…”
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Thermoresponsive lipids engineered magnetic nanoparticles for spatiotemporal delivery of hesperidin to inflammatory sites in animal model
Published in Pharmaceutical development and technology (08-08-2024)“…Thermoresponsive nanoparticles are exploited as drug-delivery vehicles that release their payload upon increment in temperature. We prepared and characterized…”
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Cinnamic acid and lactobionic acid based nanoformulations as a potential antiamoebic therapeutics
Published in Experimental parasitology (01-03-2023)“…Acanthamoeba castellanii causes granulomatous amoebic encephalitis, an uncommon but severe brain infection and sight-threatening Acanthamoeba keratitis. Most…”
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Design of absorption enhancer containing self-nanoemulsifying drug delivery system (SNEDDS) for curcumin improved anti-cancer activity and oral bioavailability
Published in Journal of molecular liquids (15-02-2021)“…Curcumin is a versatile natural anticancer molecule with higher level of safety; however, its clinical applicability is hindered by its physico-chemical…”
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Design and development of permeation enhancer containing self-nanoemulsifying drug delivery system (SNEDDS) for ceftriaxone sodium improved oral pharmacokinetics
Published in Journal of molecular liquids (01-09-2019)“…Ceftriaxone sodium cannot be delivered orally due to its lower permeability and gastric instability. Self-nanoemulsifying drug delivery systems (SNEDDS)…”
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13
Boosting photo-induced antimicrobial activity of lignin nanoparticles with curcumin and zinc oxide
Published in International journal of biological macromolecules (31-12-2023)“…Lignin nanoparticles have gained increasing attention as a potential antimicrobial agent due to their biocompatibility, biodegradability, and low toxicity…”
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Design and development of lipid modified chitosan containing muco-adhesive self-emulsifying drug delivery systems for cefixime oral delivery
Published in Chemistry and physics of lipids (01-03-2021)“…[Display omitted] •The development of SNEDDS based on the higher solubilizing capability of cefixime.•The SNEDDS droplets were coated with acyl-chitosan to…”
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Synthesis and characterization of cinnamic acid based glyceride and its application for developing self-nanoemulsifying drug delivery system for curcumin oral delivery
Published in Journal of molecular structure (05-09-2022)“…•Cinnamic acid based glycerideshave successfully synthesized.•DCG was used as an oil phase in the development of SNEDDS.•Synthesized glyceride (DCG) was…”
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Nanomedicine: Patuletin-conjugated with zinc oxide exhibit potent effects against Gram-negative and Gram-positive bacterial pathogens
Published in Biometals (01-10-2024)“…With the emergence of drug-resistance, there is a need for novel anti-bacterials or to enhance the efficacy of existing drugs. In this study, Patuletin (PA), a…”
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Highly functionalized pH-triggered supramolecular nanovalve for targeted cancer chemotherapy
Published in Pharmaceutical development and technology (08-08-2024)“…Chemotherapeutic drug delivery systems are commonly limited by their short half-lives, poor bioavailability, and unsuccessful targetability. Herein,…”
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Targeted pH-responsive delivery of rosmarinic acid via phenylboronic acid functionalized mesoporous silica nanoparticles for liver and lung cancer therapy
Published in Pharmaceutical development and technology (02-07-2024)“…Currently, chemotherapy is one of the most practiced approaches for the treatment of cancers. However, existing chemotherapeutic drugs have poor aqueous…”
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Synthesis and characterization of honey based hybrid dental implants with enhanced antibacterial activity
Published in Pakistan journal of pharmaceutical sciences (01-03-2024)“…Dental implants are commonly used for tooth replacement tools due to their good oral rehabilitation and reconstruction capacities. Dental implants treatment…”
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Antibacterial effects of quercetagetin are significantly enhanced upon conjugation with chitosan engineered copper oxide nanoparticles
Published in Biometals (01-02-2024)“…The development of antibiotic alternatives that entail distinctive chemistry and modes of action is necessary due to the threat posed by drug resistance…”
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