Search Results - "Kawata, Kyozo"

Practical Application of Oxidation Using a Novel Na2WO4−H2O2 System under Neutral Conditions for Scale-Up Manufacturing of 12α-Hydroxy-3-oxooleanano-28,13-lactone: Key Intermediate of Endothelin A Receptor Antagonist S-0139 by Hida, Takemasa, Fukui, Yuuki, Kawata, Kyozo, Kabaki, Mikio, Masui, Toshiaki, Fumoto, Masataka, Nogusa, Hideo

“…Novel alcohol oxidation using a Na2WO4−H2O2 system was applied to manufacture 12α-hydroxy-3-oxooleanano-28,13-lactone which is a key intermediate of S-0139…”
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Practical Diastereoselective Synthesis and Scale-up Study of (+)-2-((1 R ,2 R ,3 R ,5 S )-2-Amino-6,6-dimethylbicyclo[3.1.1]hept-3-yl)ethanol: A Key Intermediate of the Novel Prostaglandin D 2 Receptor Antagonist S-5751 by Hida, Takemasa, Mitsumori, Susumu, Honma, Tsunetoshi, Hiramatsu, Yoshiharu, Hashizume, Hiroshi, Okada, Tetsuo, Kakinuma, Makoto, Kawata, Kyozo, Oda, Katsuo, Hasegawa, Aiko, Masui, Toshiaki, Nogusa, Hideo

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Practical Diastereoselective Synthesis and Scale-up Study of (+)-2-((1R,2R,3R,5S)-2-Amino-6,6-dimethylbicyclo[3.1.1]hept-3-yl)ethanol: A Key Intermediate of the Novel Prostaglandin D2 Receptor Antagonist S-5751 by Hida, Takemasa, Mitsumori, Susumu, Honma, Tsunetoshi, Hiramatsu, Yoshiharu, Hashizume, Hiroshi, Okada, Tetsuo, Kakinuma, Makoto, Kawata, Kyozo, Oda, Katsuo, Hasegawa, Aiko, Masui, Toshiaki, Nogusa, Hideo

“…A new synthetic process was developed for (+)-2-((1R,2R,3R,5S)-2-amino-6,6-dimethylbicyclo[3.1.1]hept-3-yl)ethanol, a key intermediate of S-5751…”
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Practical Application of Oxidation Using a Novel Na 2 WO 4 −H 2 O 2 System under Neutral Conditions for Scale-Up Manufacturing of 12α-Hydroxy-3-oxooleanano-28,13-lactone: Key Intermediate of Endothelin A Receptor Antagonist S-0139 by Hida, Takemasa, Fukui, Yuuki, Kawata, Kyozo, Kabaki, Mikio, Masui, Toshiaki, Fumoto, Masataka, Nogusa, Hideo

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New γ-fluoromethotrexates modified in the pteridine ring: synthesis and in vitro immunosuppressive activity by Kokuryo, Yoshitsugu, Nakatani, Takuji, Kakinuma, Makoto, Kabaki, Mikio, Kawata, Kyozo, Kugimiya, Akira, Kawada, Kenji, Matsumoto, Mitsunobu, Suzuki, Ryuji, Ohtani, Mitsuaki

“…Our continuing program to develop new antifolate drugs useful against rheumatoid arthritis led us to modify the pteridine ring of γ-fluoromethotrexate…”
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Synthesis and Evaluation of Novel Fluorinated Methotrexate Derivatives for Application to Rheumatoid Arthritis Treatment by Kokuryo, Yoshitsugu, Kawata, Kyozo, Nakatani, Takuji, Kugimiya, Akira, Tamura, Yoshinori, Kawada, Kenji, Matsumoto, Mitsunobu, Suzuki, Ryuji, Kuwabara, Kenji, Hori, Yozo, Ohtani, Mitsuaki

“…An ongoing search for new antifolate drugs useful against rheumatoid arthritis (RA) led us to prepare new methotrexate (MTX) derivatives containing…”
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One-step synthesis of bridged aziridines by Nagata, Wataru, Hirai, Shoichi, Kawata, Kyozo, Aoki, Tsutomu

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A stereochemical controlled total synthesis of DL-ibogamine and DL-epiibogamine by Nagata, Wataru, Hirai, Shoichi, Okumura, Tamotsu, Kawata, Kyozo

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Additions and Corrections - A New Method for Isoquinuclidine Synthesis. A Total Synthesis of Desethylibogamine by Nagata, Wataru, Hirai, Shoichi, Kawata, Kyozo, Okumura, Tamotsu

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A stereochemically controlled total synthesis of dl-ibogamine and dl-epiibogamine by Nagata, W, Hirai, S, Okumura, T, Kawata, K

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New method for isoquinuclidine synthesis. Total synthesis of desethylibogamine by Nagata, Wataru, Hirai, Shoichi, Kawata, Kyozo, Okumura, Tamotsu

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