Search Results - "Kawashima, Hidekazu"

Radioimmunotherapy: A Specific Treatment Protocol for Cancer by Cytotoxic Radioisotopes Conjugated to Antibodies by Kawashima, Hidekazu

“…Radioimmunotherapy (RIT) represents a selective internal radiation therapy, that is, the use of radionuclides conjugated to tumor-directed monoclonal…”
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Plantainoside B in Bacopa monniera Binds to Aβ Aggregates Attenuating Neuronal Damage and Memory Deficits Induced by Aβ by Fukuda, Aina, Nakashima, Souichi, Oda, Yoshimi, Nishimura, Kaneyasu, Kawashima, Hidekazu, Kimura, Hiroyuki, Ohgita, Takashi, Kawashita, Eri, Ishihara, Keiichi, Hanaki, Aoi, Okazaki, Mizuki, Matsuda, Erika, Tanaka, Yui, Nakamura, Seikou, Matsumoto, Takahiro, Akiba, Satoshi, Saito, Hiroyuki, Matsuda, Hisashi, Takata, Kazuyuki

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by dementia. The most characteristic pathological changes in AD brain include…”
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Copper-mediated radioiodination and radiobromination via aryl boronic precursor and its application to 125I/77Br–labeled prostate-specific membrane antigen imaging probes by Kondo, Yuto, Kimura, Hiroyuki, Sasaki, Ichiro, Watanabe, Shigeki, Ohshima, Yasuhiro, Yagi, Yusuke, Hattori, Yasunao, Koda, Manami, Kawashima, Hidekazu, Yasui, Hiroyuki, Ishioka, Noriko S.

“…[Display omitted] Prostate-specific membrane antigen (PSMA), expressed in prostate cancer cells, is being investigated extensively worldwide as a target for…”
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Synthesis and biological evaluation of Tc-99m-cyclopentadienyltricarbonyl-technetium-labeled A-85380: An imaging probe for single-photon emission computed tomography investigation of nicotinic acetylcholine receptors in the brain by Kimura, Hiroyuki, Ueda, Masashi, Kawashima, Hidekazu, Arimitsu, Kenji, Yagi, Yusuke, Saji, Hideo

“…[Display omitted] We have designed (S)-(5-(azetidin-2-ylmethoxy)pyridine-3-yl)methyl cyclopentadienyltricarbonyl technetium carboxylate ([99mTc]CPTT–A–E) with…”
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Copper‐mediated radioiodination reaction through aryl boronic acid or ester precursor and its application to direct radiolabeling of a cyclic peptide by Kondo, Yuto, Kimura, Hiroyuki, Fukumoto, Chiaki, Yagi, Yusuke, Hattori, Yasunao, Kawashima, Hidekazu, Yasui, Hiroyuki

“…A copper‐mediated radioiodination using aryl boronic precursors is attracting attention as a solution to oxidative iododestannylation and nickel‐mediated…”
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A Putative Single-Photon Emission CT Imaging Tracer for Erythropoietin-Producing Hepatocellular A2 Receptor by Furukawa, Takenori, Kimura, Hiroyuki, Torimoto, Hanae, Yagi, Yusuke, Kawashima, Hidekazu, Arimitsu, Kenji, Yasui, Hiroyuki

“…Erythropoietin-producing hepatocellular (Eph) receptors are receptor tyrosine kinases involved in cell–cell contact. The EphA2 receptor is associated with…”
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Altered striatal circuits underlie characteristic personality traits in Parkinson’s disease by Ishii, Toru, Sawamoto, Nobukatsu, Tabu, Hayato, Kawashima, Hidekazu, Okada, Tomohisa, Togashi, Kaori, Takahashi, Ryosuke, Fukuyama, Hidenao

“…Patients with Parkinson’s disease (PD) have been suggested to share personality traits characterised by low novelty-seeking and high harm-avoidance. Although a…”
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Synthesis and evaluation of a [18F]formyl–Met–Leu–Phe derivative: A positron emission tomography imaging probe for bacterial infections by Kimura, Hiroyuki, Yamauchi, Saki, Kawashima, Hidekazu, Arimitsu, Kenji, Yagi, Yusuke, Nakamoto, Yuji, Togashi, Kaori, Ono, Masahiro, Saji, Hideo

“…[Display omitted] •Development of a 18F-labeled fMLF derivative targeting formyl peptide receptor.•fMLFXYk(FB)k has a high affinity for formyl peptide…”
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Synthesis and Biological Evaluation of a Novel Sugar-Conjugated Platinum(II) Complex Having a Tumor-Targeting Effect by Omokawa, Marina, Kimura, Hiroyuki, Arimitsu, Kenji, Yagi, Yusuke, Hattori, Yasunao, Kawashima, Hidekazu, Naito, Yuki, Yasui, Hiroyuki

“…We designed and synthesized a novel platinum complex conjugated with 2-fluorinated 2-deoxyglucoside, named FGC-Pt, to capitalize on the Warburg effect and…”
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Continuous-Flow Synthesis of N-Succinimidyl 4-[18F]fluorobenzoate Using a Single Microfluidic Chip by Kimura, Hiroyuki, Tomatsu, Kenji, Saiki, Hidekazu, Arimitsu, Kenji, Ono, Masahiro, Kawashima, Hidekazu, Iwata, Ren, Nakanishi, Hiroaki, Ozeki, Eiichi, Kuge, Yuji, Saji, Hideo

“…In the field of positron emission tomography (PET) radiochemistry, compact microreactors provide reliable and reproducible synthesis methods that reduce the…”
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Three-dimensional brain phantom containing bone and grey matter structures with a realistic head contour by Iida, Hidehiro, Hori, Yuki, Ishida, Kenji, Imabayashi, Etsuko, Matsuda, Hiroshi, Takahashi, Masaaki, Maruno, Hirotaka, Yamamoto, Akihide, Koshino, Kazuhiro, Enmi, Junichiro, Iguchi, Satoshi, Moriguchi, Tetsuaki, Kawashima, Hidekazu, Zeniya, Tsutomu

“…Introduction A physical 3-dimensional phantom that simulates PET/SPECT images of static regional cerebral blood flow in grey matter with a realistic head…”
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L-Serine-Modified Poly-L-Lysine as a Biodegradable Kidney-Targeted Drug Carrier for the Efficient Radionuclide Therapy of Renal Cell Carcinoma by Katsumi, Hidemasa, Kitada, Sho, Yasuoka, Shintaro, Takashima, Rie, Imanishi, Tomoki, Tanaka, Rina, Matsuura, Satoru, Kimura, Hiroyuki, Kawashima, Hidekazu, Morishita, Masaki, Yamamoto, Akira

“…In the present study, L-serine (Ser)-modified poly-L-lysine (PLL) was synthesized to develop a biodegradable, kidney-targeted drug carrier for efficient…”
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111 In-DTPA-d-Phe -1 -Asp 0 -d-Phe 1 -octreotide exhibits higher tumor accumulation and lower renal radioactivity than 111 In-DTPA-d-Phe 1 -octreotide by Oshima, Nobuhiro, Akizawa, Hiromichi, Kitaura, Hirotake, Kawashima, Hidekazu, Zhao, Songji, Zhao, Yan, Nishijima, Ken-Ichi, Kitamura, Yoji, Arano, Yasushi, Kuge, Yuji, Ohkura, Kazue

“…In-DTPA-d-Phe -octreotide scintigraphy is an important method of detecting neuroendocrine tumors. We previously reported that a new derivative of In-DTPA-d-Phe…”
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Synthesis and evaluation of (−)- and (+)-[11C]galanthamine as PET tracers for cerebral acetylcholinesterase imaging by Kimura, Hiroyuki, Kawai, Tomoki, Hamashima, Yoshio, Kawashima, Hidekazu, Miura, Kenji, Nakaya, Yuta, Hirasawa, Makoto, Arimitsu, Kenji, Kajimoto, Tetsuya, Ohmomo, Yoshiro, Ono, Masahiro, Node, Manabu, Saji, Hideo

“…Sagittal PET image of (−)-[11C]galanthamine in the ddY mouse. Improved radiopharmaceuticals for imaging cerebral acetylcholinesterase (AChE) are needed for the…”
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Application of Microreactor to the Preparation of C-11-Labeled Compounds via O-[11C]Methylation with [11C]CH3I: Rapid Synthesis of [11C]Raclopride by Kawashima, Hidekazu, Kimura, Hiroyuki, Nakaya, Yuta, Tomatsu, Kenji, Arimitsu, Kenji, Nakanishi, Hiroaki, Ozeki, Eiichi, Kuge, Yuji, Saji, Hideo

“…A new radiolabeling method using a microreactor was developed for the rapid synthesis of [11C]raclopride. A chip bearing a Y-shaped mixing junction with a 200…”
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FDG PET as a prognostic predictor in the early post-therapeutic evaluation for unresectable hepatocellular carcinoma by Higashi, Tatsuya, Hatano, Etsuro, Ikai, Iwao, Nishii, Ryuichi, Nakamoto, Yuji, Ishizu, Koichi, Suga, Tsuyoshi, Kawashima, Hidekazu, Togashi, Kaori, Seo, Satoru, Kitamura, Koji, Takada, Yasuji, Kamimoto, Shinji

“…Purpose To elucidate the prognostic role of post-therapeutic 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography (PET), we conducted a…”
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N‐methyl‐d‐aspartate receptor dysfunction in the prefrontal cortex of stroke‐prone spontaneously hypertensive rat/Ezo as a rat model of attention deficit/hyperactivity disorder by Shikanai, Hiroki, Oshima, Nobuhiro, Kawashima, Hidekazu, Kimura, Shin‐ichi, Hiraide, Sachiko, Togashi, Hiroko, Iizuka, Kenji, Ohkura, Kazue, Izumi, Takeshi

“…Aim We previously reported that stroke‐prone spontaneously hypertensive rat/Ezo (SHRSP/Ezo) has high validity as an attention deficit/hyperactivity disorder…”
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Gene and protein analysis of brain derived neurotrophic factor expression in relation to neurological recovery induced by an enriched environment in a rat stroke model by Hirata, Kenji, Kuge, Yuji, Yokota, Chiaki, Harada, Akina, Kokame, Koichi, Inoue, Hiroyasu, Kawashima, Hidekazu, Hanzawa, Hiroko, Shono, Yuji, Saji, Hideo, Minematsu, Kazuo, Tamaki, Nagara

“…► Postischemic enriched environment improved motor function and increased synapse. ► RT-PCR, Western blotting, and immunostaining measured mature BDNF and…”
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Adequacy of a Compartment Model for CMRO2 Quantitation Using 15O-Labeled Oxygen and PET: A Clearance Measurement of 15O-Radioactivity Following Intracarotid Bolus Injection of 15O-Labeled Oxyhemoglobin on Macaca Fascicularis by Iida, Hidehiro, Iguchi, Satoshi, Teramoto, Noboru, Koshino, Kazuhiro, Zeniya, Tsutomu, Yamamoto, Akihide, Kudomi, Nobuyuki, Moriguchi, Tetsuaki, Hori, Yuki, Enmi, Junichiro, Kawashima, Hidekazu, Shah, Nadim Joni, Nakagawara, Jyoji

“…We aimed at evaluating the adequacy of the commonly employed compartmental model for quantitation of cerebral metabolic rate of oxygen (CMRO2) using…”
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Significance of chronic marked hyperglycemia on FDG-PET: is it really problematic for clinical oncologic imaging? by Hara, Tadashi, Higashi, Tatsuya, Nakamoto, Yuji, Suga, Tsuyoshi, Saga, Tsuneo, Ishimori, Takayoshi, Ishizu, Koichi, Kawashima, Hidekazu, Kawase, Shigeto, Matsumoto, Keiichi, Togashi, Kaori

“…Objectives The purpose of this study was to evaluate the adverse effects of chronic marked hyperglycemia on clinical diagnostic performance of positron…”
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