Search Results - "Kawashima, Aki"

Tandem Alkylation–Second-Order Asymmetric Transformation Protocol for the Preparation of Phenylalanine-Type Tailor-Made α‑Amino Acids by Takeda, Ryosuke, Kawashima, Aki, Yamamoto, Junya, Sato, Tatsunori, Moriwaki, Hiroki, Izawa, Kunisuke, Abe, Hidenori, Soloshonok, Vadim A

“…In this work, we disclose an advanced general process for the synthesis of tailor-made α-amino acids (α-AAs) via tandem alkylation–second-order asymmetric…”
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DDB Accumulates at DNA Damage Sites Immediately after UV Irradiation and Directly Stimulates Nucleotide Excision Repair by Wakasugi, Mitsuo, Kawashima, Aki, Morioka, Hiroshi, Linn, Stuart, Sancar, Aziz, Mori, Toshio, Nikaido, Osamu, Matsunaga, Tsukasa

“…Damaged DNA-binding protein, DDB, is a heterodimer of p127 and p48 with a high specificity for binding to several types of DNA damage. Mutations in the p48…”
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Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging [alpha]-Amino Acids by Nian, Yong, Wang, Jiang, Zhou, Shengbin, Wang, Shuni, Moriwaki, Hiroki, Kawashima, Aki, Soloshonok, Vadim A, Liu, Hong

“…Structurally simple and inexpensive chiral tridentate ligands were employed for substantially advancing the purely chemical dynamic kinetic resolution (DKR) of…”
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Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging α-Amino Acids by Nian, Yong, Wang, Jiang, Zhou, Shengbin, Wang, Shuni, Moriwaki, Hiroki, Kawashima, Aki, Soloshonok, Vadim A., Liu, Hong

“…Structurally simple and inexpensive chiral tridentate ligands were employed for substantially advancing the purely chemical dynamic kinetic resolution (DKR) of…”
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Chemical Dynamic Kinetic Resolution and S/R Interconversion of Unprotected α-Amino Acids by Takeda, Ryosuke, Kawamura, Akie, Kawashima, Aki, Sato, Tatsunori, Moriwaki, Hiroki, Izawa, Kunisuke, Akaji, Kenichi, Wang, Shuni, Liu, Hong, Aceña, José Luis, Soloshonok, Vadim A.

“…Reported herein is the first purely chemical method for the dynamic kinetic resolution (DKR) of unprotected racemic α‐amino acids (α‐AAs), a method which can…”
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Operationally Convenient and Scalable Asymmetric Synthesis of (2 S )‐ and (2 R )‐α‐(Methyl)cysteine Derivatives through Alkylation of Chiral Alanine Schiff Base Ni II Complexes by Yamamoto, Junya, Kawashima, Aki, Kawamura, Akie, Abe, Hidenori, Moriwaki, Hiroki, Shibata, Norio, Soloshonok, Vadim A.

“…This research demonstrates that the methylation of N ‐benzyl cysteine Schiff base derived Ni II complexes leads to the formation of the corresponding…”
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Asymmetric Synthesis of Aromatic and Heteroaromatic α-Amino Acids Using a Recyclable Axially Chiral Ligand by Li, Jia, Zhou, Shengbin, Wang, Jiang, Kawashima, Aki, Moriwaki, Hiroki, Soloshonok, Vadim A., Liu, Hong

“…In this work, we introduce a new chiral nucleophilic glycine equivalent containing a recyclable axially chiral ligand. As the first synthetic application of…”
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Purely Chemical Approach for Preparation of d‑α-Amino Acids via (S)‑to‑(R)‑Interconversion of Unprotected Tailor-Made α‑Amino Acids by Nian, Yong, Wang, Jiang, Zhou, Shengbin, Dai, Wenhao, Wang, Shuni, Moriwaki, Hiroki, Kawashima, Aki, Soloshonok, Vadim A, Liu, Hong

“…Unnatural (R)-α-amino acids (α-AAs) are in growing demand in the biomedical research and pharmaceutical industries. In this work, we present development of a…”
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Asymmetric Synthesis of Aromatic and Heteroaromatic [alpha]-Amino Acids Using a Recyclable Axially Chiral Ligand by Li, Jia, Zhou, Shengbin, Wang, Jiang, Kawashima, Aki, Moriwaki, Hiroki, Soloshonok, Vadim A, Liu, Hong

“…In this work, we introduce a new chiral nucleophilic glycine equivalent containing a recyclable axially chiral ligand. As the first synthetic application of…”
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Chemical Dynamic Thermodynamic Resolution and S/R Interconversion of Unprotected Unnatural Tailor-made α‑Amino Acids by Wang, Shuni, Zhou, Shengbin, Wang, Jiang, Nian, Yong, Kawashima, Aki, Moriwaki, Hiroki, Aceña, José L, Soloshonok, Vadim A, Liu, Hong

“…Described here is an advanced, general method for purely chemical dynamic thermodynamic resolution and S/R interconversion of unprotected tailor-made α-amino…”
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Operationally Convenient and Scalable Asymmetric Synthesis of (2S)‐ and (2R)‐α‐(Methyl)cysteine Derivatives through Alkylation of Chiral Alanine Schiff Base NiII Complexes by Yamamoto, Junya, Kawashima, Aki, Kawamura, Akie, Abe, Hidenori, Moriwaki, Hiroki, Shibata, Norio, Soloshonok, Vadim A.

“…This research demonstrates that the methylation of N‐benzyl cysteine Schiff base derived NiII complexes leads to the formation of the corresponding…”
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Operationally Convenient and Scalable Asymmetric Synthesis of (2S)- and (2R)-[alpha]-(Methyl)cysteine Derivatives through Alkylation of Chiral Alanine Schiff Base NiII Complexes by Yamamoto, Junya, Kawashima, Aki, Kawamura, Akie, Abe, Hidenori, Moriwaki, Hiroki, Shibata, Norio, Soloshonok, Vadim A

“…This research demonstrates that the methylation of N-benzyl cysteine Schiff base derived NiII complexes leads to the formation of the corresponding…”
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Advanced asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by alkylation/cyclization of newly designed axially chiral Ni(II) complex of glycine Schiff base by Kawashima, Aki, Shu, Shuangjie, Takeda, Ryosuke, Kawamura, Akie, Sato, Tatsunori, Moriwaki, Hiroki, Wang, Jiang, Izawa, Kunisuke, Aceña, José Luis, Soloshonok, Vadim A., Liu, Hong

“…Asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid (vinyl-ACCA) is in extremely high demand due to the pharmaceutical importance of…”
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Asymmetric Synthesis of Aromatic and Heteroaromatic [alpha]-Amino Acids Using a Recyclable Axially Chiral Ligand by Li, Jia, Zhou, Shengbin, Wang, Jiang, Kawashima, Aki, Moriwaki, Hiroki, Soloshonok, Vadim A, Liu, Hong

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Asymmetric Synthesis of Aromatic and Heteroaromatic α-Amino Acids Using a Recyclable Axially Chiral Ligand by Li, Jia, Zhou, Shengbin, Wang, Jiang, Kawashima, Aki, Moriwaki, Hiroki, Soloshonok, Vadim A., Liu, Hong

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Inside Cover: Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging [alpha]-Amino Acids by Nian, Yong, Wang, Jiang, Zhou, Shengbin, Wang, Shuni, Moriwaki, Hiroki, Kawashima, Aki, Soloshonok, Vadim A, Liu, Hong

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Inside Cover: Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging α-Amino Acids (Angew. Chem. Int. Ed. 44/2015) by Nian, Yong, Wang, Jiang, Zhou, Shengbin, Wang, Shuni, Moriwaki, Hiroki, Kawashima, Aki, Soloshonok, Vadim A., Liu, Hong

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Correction to “Chemical Dynamic Thermodynamic Resolution and S/R Interconversion of Unprotected Unnatural Tailor-made α‑Amino Acids” by Wang, Shuni, Zhou, Shengbin, Wang, Jiang, Nian, Yong, Kawashima, Aki, Moriwaki, Hiroki, Aceña, José L, Soloshonok, Vadim A, Liu, Hong

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Design and synthesis of (S)- and (R)-α-(phenyl)ethylamine-derived NH-type ligands and their application for the chemical resolution of α-amino acids by Takeda, Ryosuke, Kawamura, Akie, Kawashima, Aki, Moriwaki, Hiroki, Sato, Tatsunori, Aceña, José Luis, Soloshonok, Vadim A

“…This work presents the first chemical approach for the resolution of α-amino acids offering the following advantages: (1) The specially designed resolving…”
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Chemical Dynamic Kinetic Resolution and S/RInterconversion of Unprotected [alpha]-Amino Acids by Takeda, Ryosuke, Kawamura, Akie, Kawashima, Aki, Sato, Tatsunori, Moriwaki, Hiroki, Izawa, Kunisuke, Akaji, Kenichi, Wang, Shuni, Liu, Hong, Acena, José Luis, Soloshonok, Vadim A

“…Reported herein is the first purely chemical method for the dynamic kinetic resolution (DKR) of unprotected racemic [alpha]-amino acids ([alpha]-AAs), a method…”
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