Search Results - "Kawaratani, Yasuyuki"

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    Growth Inhibition of Human Colon Cancer Cell Line HCT116 by Bis[2-(acylamino)phenyl] Disulfide and Its Action Mechanism by Yamakawa, Satoshi, Demizu, Aya, Kawaratani, Yasuyuki, Nagaoka, Yasuo, Terada, Yuji, Maruyama, Sakiko, Uesato, Shinichi

    Published in Biological & pharmaceutical bulletin (01-05-2008)
    “…Our laboratory has been investigating the use of compounds which disrupt β-catenin/T cell factor (TCF) binding to treat human colon cancer. There are several…”
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    Journal Article
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    New microtubule polymerization inhibitors comprising a nitrooxymethylphenyl group by Kawaratani, Yasuyuki, Harada, Tomohiko, Hirata, Yoshiyuki, Nagaoka, Yasuo, Tanimura, Susumu, Shibano, Makio, Taniguchi, Masahiko, Yasuda, Masahide, Baba, Kimiye, Uesato, Shinichi

    Published in Bioorganic & medicinal chemistry (01-07-2011)
    “…New compounds possessing a nitrooxymethylphenyl group were designed. Compounds 2a and 8a disrupted the formation of microtubules as did vincristine. The…”
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    Discovery of new low-molecular-weight p53–Mdmx disruptors and their anti-cancer activities by Uesato, Shinichi, Matsuura, Yoshihiro, Matsue, Saki, Sumiyoshi, Takaaki, Hirata, Yoshiyuki, Takemoto, Suzuho, Kawaratani, Yasuyuki, Yamai, Yusuke, Ishida, Kyoji, Sasaki, Tsutomu, Enari, Masato

    Published in Bioorganic & medicinal chemistry (15-04-2016)
    “…[Display omitted] Although several p53–Mdm2-binding disruptors have been identified to date, few studies have been published on p53–Mdmx-interaction…”
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