Search Results - "Kawano, Noriaki"
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1
Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
Published in Nature communications (05-02-2016)“…Opiates such as morphine and codeine are mainly obtained by extraction from opium poppies. Fermentative opiate production in microbes has also been…”
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2
Circulating CD34+ cells of primary myelofibrosis patients contribute to myeloid-dominant hematopoiesis and bone marrow fibrosis in immunodeficient mice
Published in International journal of hematology (01-02-2022)“…Introduction Primary myelofibrosis (PMF) is a clonal stem cell disorder characterized by myeloid dominant hematopoiesis and dysregulated proliferation of…”
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3
Phenanthroindolizine alkaloids from Boehmeria sieboldiana leaves exhibit cytotoxicity against human cancer cell lines
Published in Journal of natural medicines (01-06-2022)“…To explore useful natural compounds from indigenous medicinal plants, the cytotoxic properties from a methanolic extract of Boehmeria sieboldiana leaves…”
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4
Near-Infrared Metabolic Profiling for Discrimination of Apricot and Peach Kernels
Published in Chemical & pharmaceutical bulletin (01-12-2022)“…Apricot and Peach Kernels are commercial crude drugs used in many formulas of traditional Japanese medicine, Kampo. Although their applications are quite…”
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5
De Novo RNA Sequencing and Expression Analysis of Aconitum carmichaelii to Analyze Key Genes Involved in the Biosynthesis of Diterpene Alkaloids
Published in Molecules (Basel, Switzerland) (05-12-2017)“…is an important medicinal herb used widely in China, Japan, India, Korea, and other Asian countries. While extensive research on the characterization of…”
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6
Genetic diversity of Amomum xanthioides and its related species from Southeast Asia and China
Published in Journal of natural medicines (01-09-2021)“…Amomum Semen, the seed mass of Amomum xanthioides, has been imported from Southeast Asia and China and used for the treatment of gastric and intestinal…”
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Screening of growth inhibitors for epithelial–mesenchymal transition-induced cells by TGF-β from plant-based sources identified the active compound hydroxychavicol from Piper bitle
Published in Journal of natural medicines (01-06-2024)“…Epithelial–mesenchymal transition (EMT) has recently been associated with cancer invasion, metastasis, and resistance. In our previous study, we discovered…”
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Serial evaluation of the pharmacokinetics of ponatinib in patients with CML and Ph + ALL
Published in International journal of hematology (01-10-2021)“…Although tyrosine kinase inhibitors (TKIs) play a crucial role in the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute…”
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9
Improved quantitative analysis of tenuifolin using hydrolytic continuous-flow system to build prediction models for its content based on near-infrared spectroscopy
Published in Journal of natural medicines (01-03-2024)“…This study used two types of analyses and statistical calculations on powdered samples of Polygala root (PR) and Senega root (SR): (1) determination of saponin…”
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10
One-pot discriminant LC/MS quantitative analysis of ephedrine and pseudoephedrine using Finger Masher and their distribution in the aerial stems of Ephedra plants
Published in Journal of natural medicines (01-06-2021)“…A discriminant LC/MS quantitative analysis of ephedrine (EP) and pseudoephedrine (PEP) in Ephedrae herba was performed. Aerial parts of three Ephedra species…”
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11
HLA loci predisposing to immune TTP in Japanese: potential role of the shared ADAMTS13 peptide bound to different HLA-DR
Published in Blood (25-06-2020)“…Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare autoimmune disorder caused by neutralizing anti-ADAMTS13 autoantibodies. In white…”
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12
Immunohistopathological Analysis of Extramedullary Hematopoiesis and Angiogenesis of Spleen in a Case of Primary Myelofibrosis with Huge Splenomegaly
Published in The Tohoku Journal of Experimental Medicine (01-02-2022)“…Although splenomegaly is one of the important signs of primary myelofibrosis, the differential diagnosis varies from malignant disorders to benign disorders,…”
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13
Endobronchial Mucosa-associated Lymphoid Tissue Lymphoma: A Report of Two Cases and a Review of the Literature
Published in Internal Medicine (01-08-2018)“…Primary endobronchial mucosa-associated lymphoid tissue lymphoma (EML) is rare. We reviewed 20 cases of EML, including ours and case reports. We found that the…”
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14
Secondary Skin Cancer in a Case with Long-term Voriconazole after Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia
Published in Internal Medicine (15-09-2022)“…Secondary malignancies that develop after allogeneic-hematopoietic stem cell transplantation (allo-HSCT) have become serious issues. A 47-year-old man who…”
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Clinical Features of Disseminated Intravascular Coagulation According to the French-American-British Classification in Patients With Acute Leukemia and Thrombomodulin Alfa Treatment—A Cohort Study Using a Postmarketing Surveillance Database
Published in Clinical and applied thrombosis/hemostasis (01-12-2021)“…The aims of this study were to analyze the clinical features of a large number of cases with disseminated intravascular coagulation (DIC) associated with acute…”
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16
Development of a determination method for quality control markers utilizing metabolic profiling and its application on processed Zingiber officinale Roscoe rhizome
Published in Journal of natural medicines (01-09-2024)“…This study established an Orthogonal Partial Least Squares (OPLS) model combining 1 H-NMR and GC-MS data to identify characteristic metabolites in complex…”
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17
Mutagenetic and anti-allergic studies for evaluation of extracts of Coptis Rhizome produced by an artificial hydroponic system
Published in Journal of natural medicines (01-06-2019)“…As a part of the investigation of the safety and efficacy of the cultivated Coptis japonica rhizome extracts using an artificial hydroponic cultivation system,…”
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Development of selection method for Glycyrrhiza uralensis superior clones with high-glycyrrhizic acid contents using DNA sequence polymorphisms in glycyrrhizic acid biosynthetic genes
Published in Plant Biotechnology (25-03-2021)“…Glycyrrhiza plants are important resources for sweeteners and medicines, because underground parts of them contain glycyrrhizic acid (GL), which has sweet…”
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Clinical features and chromosomal/genetic aberration in adult acute lymphoblastic leukemia in Japan: results of Fukuoka Blood & Marrow Transplant Group Studies ALL MRD 2002 and 2008
Published in International journal of hematology (01-06-2021)“…Acute lymphoblastic leukemia (ALL) is a common neoplasm in children, but less frequent in adults. Since information on clinical features and genetics of adult…”
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The clinical impact of the ratio of C-reactive protein to albumin (CAR) in patients with acute- and lymphoma-type adult T-cell leukemia-lymphoma (ATL)
Published in Journal of Clinical and Experimental Hematopathology (01-01-2023)“…Recently, the ratio of C-reactive protein to albumin (CAR) is used as an inflammatory marker that has been demonstrated to be a simple and reliable prognostic…”
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