Search Results - "Kawamura, Nanami"
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Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment
Published in Proceedings of the National Academy of Sciences - PNAS (22-10-2013)“…Primary ovarian insufficiency (POI) and polycystic ovarian syndrome are ovarian diseases causing infertility. Although there is no effective treatment for POI,…”
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2
A fungal sesquiterpene biosynthesis gene cluster critical for mutualist-pathogen transition in Colletotrichum tofieldiae
Published in Nature communications (06-09-2023)“…Plant-associated fungi show diverse lifestyles from pathogenic to mutualistic to the host; however, the principles and mechanisms through which they shift the…”
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3
Brain-Derived Neurotrophic Factor Promotes Implantation and Subsequent Placental Development by Stimulating Trophoblast Cell Growth and Survival
Published in Endocrinology (Philadelphia) (01-08-2009)“…Successful implantation of the blastocyst and subsequent placental development is essential for reproduction. Expression of brain-derived neurotrophic factor…”
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Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling Regulates Human Trophoblast Growth in an in Vivo Animal Model of Ectopic Pregnancy
Published in Endocrinology (Philadelphia) (01-03-2011)“…Paracrine signaling of the BDNF/TrkB system is important for human trophoblast growth, and its inhibition could provide medical treatment for ectopic…”
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Inhibition of Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling Suppresses Choriocarcinoma Cell Growth
Published in Endocrinology (Philadelphia) (01-07-2010)“…Brain-derived neurotrophic factor (BDNF) signals through its receptor tyrosine kinase (Trk)B to regulate the development trophoblast cells during peri- and…”
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Regulation of preimplantation embryo development by brain-derived neurotrophic factor
Published in Developmental biology (01-11-2007)“…Hormonal factors secreted by embryos and reproductive tracts are important for successful development of preimplantation embryos. We found expression of…”
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Ovarian Brain-Derived Neurotrophic Factor (BDNF) Promotes the Development of Oocytes into Preimplantation Embryos
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2005)“…Optimal development of fertilized eggs into preimplantation embryos is essential for reproduction. Although mammalian oocytes ovulated after luteinizing…”
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Inhibition of uterine sarcoma cell growth through suppression of endogenous tyrosine kinase B signaling
Published in PloS one (23-07-2012)“…Uterine leiomyosarcoma is an aggressive tumor typically found at advanced stages due to difficulties with early diagnosis. Because uterine leiomyosarcoma is…”
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Suppression of Hydatidiform Molar Growth by Inhibiting Endogenous Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling
Published in Endocrinology (Philadelphia) (01-08-2012)“…Brain-derived neurotrophic factor (BDNF)/tyrosine kinase B (TrkB) receptor signaling promotes trophoblast growth in normal and abnormal pregnancy. It also…”
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10
Paracrine regulation of the resumption of oocyte meiosis by endothelin-1
Published in Developmental biology (01-03-2009)“…Mammalian oocytes remain dormant in the diplotene stage of prophase I until the resumption of meiosis characterized by germinal vesicle breakdown (GVBD)…”
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11
Kit ligand promotes first polar body extrusion of mouse preovulatory oocytes
Published in Reproductive biology and endocrinology (03-04-2009)“…Shortly after stimulation by the preovulatory surge of luteinizing hormone (LH), oocytes arrested at the late prophase I resume meiosis characterized by…”
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Completion of Meiosis I of preovulatory oocytes and facilitation of preimplantation embryo development by glial cell line-derived neurotrophic factor
Published in Developmental biology (01-03-2008)“…Optimal maturation of oocytes and successful development of preimplantation embryos is essential for reproduction. We performed DNA microarray analyses of…”
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13
Activation of dormant follicles: a new treatment for premature ovarian failure?
Published in Current opinion in obstetrics & gynecology (01-06-2016)“…Premature ovarian failure (POF) is diagnosed by amenorrhea before 40 years of age. Owing to exhaustion of follicles in POF ovaries, egg donation is the only…”
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14
Microglia enable cross-modal plasticity by removing inhibitory synapses
Published in Cell reports (Cambridge) (30-05-2023)“…Cross-modal plasticity is the repurposing of brain regions associated with deprived sensory inputs to improve the capacity of other sensory modalities. The…”
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15
Reciprocal Connections between Parvalbumin-Expressing Cells and Adjacent Pyramidal Cells Are Regulated by Clustered Protocadherin γ
Published in eNeuro (01-10-2023)“…Functional neural circuits in the cerebral cortex are established through specific neural connections between excitatory and various inhibitory cell types…”
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Pre-ovulatory LH/hCG surge decreases C-type natriuretic peptide secretion by ovarian granulosa cells to promote meiotic resumption of pre-ovulatory oocytes
Published in Human reproduction (Oxford) (01-11-2011)“…BACKGROUND In mammalian follicles, oocytes are arrested at the diplotene stage of prophase I until meiotic resumption following the LH surge. Recently, C-type…”
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Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling
Published in Cancer medicine (Malden, MA) (01-12-2013)“…Brain‐derived neurotrophic factor (BDNF) acts through its cognate receptor tyrosine kinase‐B (TrkB) to regulate diverse physiological functions in reproductive…”
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Tumor Necrosis Factor Regulation of Apoptosis in Mouse Preimplantation Embryos and Its Antagonism by Transforming Growth Factor Alpha/Phosphatidylionsitol 3-Kinase Signaling System
Published in Biology of reproduction (01-04-2007)“…Survival and apoptosis of cells in preimplantation embryos are fundamental for successful pregnancy. Relevant to these processes, tumor necrosis factor (TNF)…”
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Tumor Necrosis Factor Regulation of Apoptosis in Mouse Preimplantation Embryos and Its Antagonism by Transforming Growth Factor Alpha/Phosphatidylionsitol 3-Kinase Signaling System1
Published in Biology of reproduction (01-04-2007)“…Survival and apoptosis of cells in preimplantation embryos are fundamental for successful pregnancy. Relevant to these processes, tumor necrosis factor (TNF)…”
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Leptin and ObRa/MEK signalling in mouse oocyte maturation and preimplantation embryo development
Published in Reproductive biomedicine online (2009)“…Abstract Recent studies indicate that LH stimulates production of ovarian paracrine factors that induce meiosis of the oocyte. DNA microarray analyses of…”
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