Search Results - "Kawamura, Atsuki"

Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons by Kawamura, Atsuki, Nishiyama, Masaaki

“…CHD8 encodes chromodomain helicase DNA-binding protein 8 and its mutation is a highly penetrant risk factor for autism spectrum disorder (ASD). CHD8 serves as…”
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The autism-associated protein CHD8 is required for cerebellar development and motor function by Kawamura, Atsuki, Katayama, Yuta, Kakegawa, Wataru, Ino, Daisuke, Nishiyama, Masaaki, Yuzaki, Michisuke, Nakayama, Keiichi I.

“…Mutations in the gene encoding the chromatin remodeler chromodomain helicase DNA-binding protein 8 (CHD8) are a highly penetrant risk factor for autism…”
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Oligodendrocyte dysfunction due to Chd8 mutation gives rise to behavioral deficits in mice by Kawamura, Atsuki, Katayama, Yuta, Nishiyama, Masaaki, Shoji, Hirotaka, Tokuoka, Kota, Ueta, Yoshifumi, Miyata, Mariko, Isa, Tadashi, Miyakawa, Tsuyoshi, Hayashi-Takagi, Akiko, Nakayama, Keiichi I

“…Abstract Mutations in the gene encoding the chromatin remodeler CHD8 are strongly associated with autism spectrum disorder (ASD). CHD8 haploinsufficiency also…”
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Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3 by Nakayama, Shogo, Yumimoto, Kanae, Kawamura, Atsuki, Nakayama, Keiichi I.

“…The ubiquitin-proteasome system regulates the abundance of many cellular proteins by mediating their targeted degradation. We previously developed a…”
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FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells by Yamauchi, Takayoshi, Nishiyama, Masaaki, Moroishi, Toshiro, Kawamura, Atsuki, Nakayama, Keiichi I.

“…FBXL5 is the substrate recognition subunit of an SCF-type ubiquitin ligase that serves as a master regulator of iron metabolism in mammalian cells. We…”
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Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain by Kawamura, Atsuki, Abe, Yoshifumi, Seki, Fumiko, Katayama, Yuta, Nishiyama, Masaaki, Takata, Norio, Tanaka, Kenji F, Okano, Hideyuki, Nakayama, Keiichi I

“…CHD8 encodes a chromatin-remodeling factor and is one of the most recurrently mutated genes in individuals with autism spectrum disorder (ASD). Although we…”
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Role of glutathione in heat-shock-induced cell death of Saccharomyces cerevisiae by Sugiyama, K, Kawamura, A, Izawa, S, Inoue, Y

“…Previously we reported that expression of GSH1 (gamma-glutamylcysteine synthetase) and GSH2 (glutathione synthetase) of the yeast Saccharomyces cerevisiae was…”
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CHD8 haploinsufficiency results in autistic-like phenotypes in mice by Katayama, Yuta, Nishiyama, Masaaki, Shoji, Hirotaka, Ohkawa, Yasuyuki, Kawamura, Atsuki, Sato, Tetsuya, Suyama, Mikita, Takumi, Toru, Miyakawa, Tsuyoshi, Nakayama, Keiichi I.

“…Heterozygous Chd8 mutant mice display autistic-like behaviours and small but global changes in brain gene expression, which are associated with delays in…”
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Chromatin remodeler CHD8 is required for spermatogonial proliferation and early meiotic progression by Nitahara, Kenta, Kawamura, Atsuki, Kitamura, Yuka, Kato, Kiyoko, Namekawa, Satoshi H, Nishiyama, Masaaki

“…Meiosis is a key step during germ cell differentiation, accompanied by the activation of thousands of genes through germline-specific chromatin reorganization…”
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Role of glutathione in heat-shock-induced cell death of Saccharomyces cerevisiae by SUGIYAMA, Kei-ichi, KAWAMURA, Atsuki, IZAWA, Shingo, INOUE, Yoshiharu

“…Previously we reported that expression of GSH1 (γ-glutamylcysteine synthetase) and GSH2 (glutathione synthetase) of the yeast Saccharomyces cerevisiae was…”
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Degradation of the endoplasmic reticulum-anchored transcription factor MyRF by the ubiquitin ligase SCF Fbxw7 in a manner dependent on the kinase GSK-3 by Nakayama, Shogo, Yumimoto, Kanae, Kawamura, Atsuki, Nakayama, Keiichi I

“…The ubiquitin-proteasome system regulates the abundance of many cellular proteins by mediating their targeted degradation. We previously developed a…”
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