Search Results - "Kawalek, J C"
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Depletion of florfenicol in lactating dairy cows after intramammary and subcutaneous administration
Published in Journal of veterinary pharmacology and therapeutics (01-12-2016)“…Eighteen Holstein dairy cows ranging in body weight from 500–700 kg and with an average milk yield of 37 ± 6 kg/day were used to investigate the depletion of…”
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Effect of recombinant porcine somatotropin (rpST) on drug disposition in swine
Published in Journal of veterinary pharmacology and therapeutics (01-02-2010)“…Kawalek, J.C., Howard, K.D. Effect of recombinant porcine somatotropin (rpST) on drug disposition in swine. J. vet. Pharmacol. Therap.33, 69–75. Treatment of…”
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Identification of Multiple Constitutive and Inducible Hepatic Cytochrome P450 Enzymes in Market Weight Swine
Published in Drug metabolism and disposition (01-06-2001)“…Constitutive swine enzymes analogous to human/rat cytochrome P450 (CYP) isoforms 1A2, 2A6, 2B1/2/6, 2D6, 2E1, 3A1, and 4A1/3 were detected by Western blot…”
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Comparison of maturation of drug-metabolizing enzymes in calves with functioning or nonfunctioning rumen
Published in American journal of veterinary research (01-11-1994)“…Drug-metabolizing enzyme activities were measured in livers from calves fed commercial milk replacer (nonfunctioning rumen [veal]), and those fed milk replacer…”
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Comparison of bovine in vivo bioavailability of two sulfamethazine oral boluses exhibiting different in vitro dissolution profiles
Published in Journal of veterinary pharmacology and therapeutics (01-12-2006)“…The bolus (or oblet) is a dosage form that can be used for the oral administration of pharmaceutical compounds to ruminating species. Unlike traditional…”
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Maturational development of drug-metabolizing enzymes in sheep
Published in American journal of veterinary research (01-11-1990)“…A qualitative and quantitative assessment was made of the development of hepatic drug-metabolizing enzymes (DME) in sheep as part of a study of the ability of…”
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Effect of Haemonchus contortus infection on the clearance of antipyrine, sulfobromophthalein, chloramphenicol, and sulfathiazole in lambs
Published in American journal of veterinary research (01-12-1990)“…A study was made to determine the effect of Haemonchus contortus parasitic infection in lambs on the clearance of several IV administered drugs. Clearance of…”
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The effect of solvents on drug metabolism in vitro
Published in Drug metabolism and disposition (01-11-1980)“…Nine water-miscible organic solvents, methanol, ethanol, acetone, ethoxyethanol, tetrahydrofuran, dioxane, dimethylformamide, acetonitrile, and dimethyl…”
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Maturational development of drug-metabolizing enzymes in dogs
Published in American journal of veterinary research (01-11-1990)“…A qualitative and quantitative assessment was made of the development of hepatic drug-metabolizing enzymes (DME) in dogs as part of a study of the ability of…”
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1-Naphthylthiourea: a mutagenic rodenticide that transforms hamster embryo cells
Published in Molecular pharmacology (01-05-1979)Get more information
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Effect of lithocholic acid on the mutagenicity of some substituted aromatic amines
Published in JNCI : Journal of the National Cancer Institute (01-08-1983)“…The effects of lithocholic acid on the mutagenicity of 24 aromatic amines in the Ames assay were examined. When lithocholic acid was added to the…”
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Purification of liver microsomal cytochrome P-448 from 3-methylcholanthrene-treated rabbits
Published in Molecular pharmacology (01-11-1975)Get more information
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Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. IX. The formation of a 455-nm metabolite-cytochrome P-450 complex
Published in Drug metabolism and disposition (01-03-1976)“…The reconstituted liver microsomal hydroxylation system was used to study the formation of a metabolite-cytochrome P-450 complex absorbing maximally at 455 nm,…”
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Separation and detection of 2-aminoanthracene and its metabolites by high-performance liquid chromatography
Published in Journal of chromatography (01-01-1980)Get more information
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Partial purification of the NADPH-dependent aldehyde reductase from bovine cardiac muscle
Published in Archives of biochemistry and biophysics (01-04-1976)Get more information
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Pig and minipig cytochromes P450
Published in Drug metabolism and disposition (01-01-2002)Get full text
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Enzymic reduction of free fatty aldehydes in bovine cardiac muscle
Published in Biochemical and biophysical research communications (16-04-1973)Get more information
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