Search Results - "Kawai, Shintaro"

Brain Region-dependent Heterogeneity and Dose-dependent Difference in Transient Microglia Population Increase during Lipopolysaccharide-induced Inflammation by Furube, Eriko, Kawai, Shintaro, Inagaki, Haruna, Takagi, Shohei, Miyata, Seiji

“…Numerous studies have reported the importance of microglial activation in various pathological conditions, whereas little attention has been given to the point…”
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Author Correction: Brain Region-dependent Heterogeneity and Dose-dependent Difference in Transient Microglia Population Increase during Lipopolysaccharide-induced Inflammation by Furube, Eriko, Kawai, Shintaro, Inagaki, Haruna, Takagi, Shohei, Miyata, Seiji

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Fulminant Type 1 Diabetes Mellitus Accompanied by Positive Conversion of Anti-insulin Antibody after the Administration of Anti-CTLA-4 Antibody Following the Discontinuation of Anti-PD-1 Antibody by Shiba, Michiru, Inaba, Hidefumi, Ariyasu, Hiroyuki, Kawai, Shintaro, Inagaki, Yuko, Matsuno, Shohei, Iwakura, Hiroshi, Yamamoto, Yuki, Nishi, Masahiro, Akamizu, Takashi

“…An 80-year-old woman with malignant melanoma received 20 cycles of anti-programmed death 1 (PD-1) antibody (nivolumab) treatment and showed normal glucose…”
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The Abundance of Antigalactose-deficient IgA1 Autoantibodies Results in Glomerular Deposition and IgA Nephropathy Recurrence After Renal Transplantation by Nakamura, Tsukasa, Shirouzu, Takayuki, Harada, Shumpei, Sugimoto, Ryusuke, Nobori, Shuji, Yoshikawa, Mikiko, Ushigome, Hidetaka, Kawai, Shintaro

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Transient increase of microglial C1q expression in the circumventricular organs of adult mouse during LPS‐induced inflammation by Kawai, Shintaro, Kurganov, Erkin, Miyata, Seiji

“…The circumventricular organs (CVOs) are the brain regions that lack the blood‐brain barrier and allow free entry of blood‐derived molecules, offering…”
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Development of a humanized mouse model to analyze antibodies specific for human leukocyte antigen (HLA) by Yanagawa, Senichiro, Tahara, Hiroyuki, Shirouzu, Takayuki, Kawai, Shintaro, Tanaka, Yuka, Ide, Kentaro, Akimoto, Shuji, Ohdan, Hideki

“…In organ transplantation, human leukocyte antigen (HLA)-mismatch grafts not only induce the activation of cellular mediated immune response but also the…”
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Intra-Liver Allograft C3d-Binding Donor-Specific Anti-HLA Antibodies Predict Rejection After Liver Transplantation by Nakamura, Tsukasa, Shirouzu, Takayuki, Sugimoto, Ryusuke, Harada, Shumpei, Yoshikawa, Mikiko, Nobori, Shuji, Ushigome, Hidetaka, Kawai, Shintaro

“…•Graft immunocomplex capture fluorescence analysis (ICFA) detects intragraft donor-specific anti-HLA antibodies (g-DSA)/HLA complexes and C3d-binding reaction…”
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Reduced Expression of Mismatch Repair Genes MSH6/MSH2 Directly Promotes Pituitary Tumor Growth via the ATR–Chk1 Pathway by Uraki, Shinsuke, Ariyasu, Hiroyuki, Doi, Asako, Kawai, Shintaro, Takeshima, Ken, Morita, Shuhei, Fukai, Junya, Fujita, Koji, Furuta, Hiroto, Nishi, Masahiro, Sugano, Kokichi, Inoshita, Naoko, Nakao, Naoyuki, Yamada, Shozo, Akamizu, Takashi

“…The mechanisms of pituitary adenoma (PA) pathogenesis and proliferation remain largely unknown. To evaluate the direct association between PA proliferation and…”
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A novel cDNA‐uPA/SCID/Rag2−/−/Jak3−/− mouse model for hepatitis virus infection and reconstruction of human immune system by Uchida, Takuro, Teraoka, Yuji, Imamura, Michio, Abe‐Chayama, Hiromi, Makokha, Grace Naswa, Hayes, Clair Nelson, Aikata, Hiroshi, Hamamura, Satoko, Ishida, Yuji, Tateno, Chise, Shirouzu, Takayuki, Kawai, Shintaro, Tanaka, Yuka, Ohdan, Hideki, Okada, Seiji, Chayama, Kazuaki

“…Although human hepatocyte‐transplanted immunodeficient mice support infection with hepatitis viruses, these mice fail to develop viral hepatitis due to the…”
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Clearance of Intra-graft Donor Specific Anti-HLA Antibodies in the Early Stage of Antibody-Mediated Rejection Following Rituximab and Apheresis Therapy in Renal Transplantation by Nakamura, Tsukasa, Yoshimura, Norio, Akioka, Kiyokazu, Shirouzu, Takayuki, Kawai, Shintaro, Imanishi, Yui, Matsuyama, Takehisa, Harada, Shumpei, Nobori, Shuji, Ushigome, Hidetaka

“…The management of acute or, in particular, chronic antibody-mediated rejection (AMR) resulting from donor-specific HLA antibodies (DSA) is a critical barrier…”
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Detection of Intragraft Anti-Blood Group A and B Antibodies Following Renal Transplantation by Nakamura, Tsukasa, Shirouzu, Takayuki, Kawai, Shintaro, Imanishi, Yui, Matsuyama, Takehisa, Harada, Shumpei, Nobori, Shuji, Yoshimura, Norio, Ushigome, Hidetaka

“…Graft immunocomplex capture fluorescence analysis is an attractive method to detect intragraft donor-specific anti-HLA antibodies. In ABO-incompatible…”
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Improved detection of donor-specific HLA-class II antibody in kidney transplant recipients by modified immunocomplex capture fluorescence analysis by Shimabukuro, Shuichi, Iwasaki, Kenta, Kawai, Shintaro, Shirouzu, Takayuki, Miwa, Yuko, Iida, Yusuke, Nakajima, Fumiaki, Horimi, Kosei, Matsuoka, Yutaka, Ashimine, Satoshi, Ishiyama, Kohei, Kobayashi, Takaaki

“…Immunocomplex capture fluorescence analysis (ICFA) which basic principle is same as Luminex crossmatch (LXM), could detect donor-specific HLA antibody (DSA)…”
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Risk Factors for Therapeutic Intervention of Remdesivir in Mild to Moderate COVID-19-A Single-Center Retrospective Study of the COVID-19 Fourth Pandemic Period in Wakayama, Japan by Tamura, Shinobu, Kaki, Takahiro, Niwa, Mayako, Yamano, Yukiko, Kawai, Shintaro, Yamashita, Yusuke, Tanaka, Harumi, Saito, Yoshinobu, Kajimoto, Yoshinori, Koizumi, Yusuke, Yamaue, Hiroki, Nakao, Naoyuki, Nojiri, Takako, Hironishi, Masaya

“…The incidence of coronavirus disease 2019 (COVID-19) has increased in Wakayama, Japan, due to the spread of the highly infectious B.1.1.7 variant. Before this…”
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Development of Novel Human Anti-HLA-Monoclonal Antibodies for Clinical Applications Using Peripheral Blood B Cells Derived from Anti-HLA Antibody-Positive Donors by Takamatsu, Hiroyuki, Zaimoku, Yoshitaka, Ozawa, Tatsuhiko, Kawai, Shintaro, Tanaka, Hidenori, Kishi, Hiroyuki, Muraguchi, Atsushi, Nakao, Shinji

“…Introduction: The development of monoclonal antibodies (mAbs) such as anti-CD20 mAb (rituximab) and anti-CD38 mAb (daratumumab) has revolutionized the…”
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Myotonic dystrophy type 1 with diabetes mellitus, mixed hypogonadism and adrenal insufficiency by Takeshima, Ken, Ariyasu, Hiroyuki, Ishibashi, Tatsuya, Kawai, Shintaro, Uraki, Shinsuke, Koh, Jinsoo, Ito, Hidefumi, Akamizu, Takashi

“…Summary Myotonic dystrophy type 1 (DM1) is an autosomal dominant multisystem disease affecting muscles, the eyes and the endocrine organs. Diabetes mellitus…”
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Synthetic Studies on Saframycin Anibiotics: An Improved Synthesis of Tricyclic Lactam Intermediate and Construction of the Core Ring System of Saframycin A by Saito, Naoki, Kimura, Shinya, Kawai, Shintaro, Azuma, Masayuki, Koizumi, Yu-ichi, Yokoya, Masashi, Umehara, Yoshifumi

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Activation of ERK in the locus coeruleus following acute noxious stimulation by Imbe, Hiroki, Okamoto, Keiichiro, Donishi, Tomohiro, Kawai, Shintaro, Enoki, Keisuke, Senba, Emiko, Kimura, Akihisa

“…Abstract In the present study, the activation of extracellular signal-regulated kinase (ERK) in the locus coeruleus (LC) following injection of formalin or…”
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Effective localization in tumor-induced osteomalacia using 68Ga-DOTATOC-PET/CT, venous sampling and 3T-MRI by Kawai, Shintaro, Ariyasu, Hiroyuki, Furukawa, Yasushi, Yamamoto, Reika, Uraki, Shinsuke, Takeshima, Ken, Warigaya, Kenji, Nakamoto, Yuji, Akamizu, Takashi

“…Summary Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by renal phosphate wasting leading to hypophosphatemia due to…”
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Myeloid-Derived Suppressor Cells Suppress Both Serum and Intragraft Donor-Specific Antibody Development in a Mouse Cardiac Transplant Model by Nakamura, Tsukasa, Shirouzu, Takayuki, Kawai, Shintaro

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Imbalanced Expression of IGF2 and PCSK4 is Associated with Overproduction of Big IGF2 in SFT with NICTH: A Pilot Study by Kawai, Shintaro, Ariyasu, Hiroyuki, Uraki, Shinsuke, Takeshima, Ken, Morita, Shuhei, Inaba, Hidefumi, Iwakura, Hiroshi, Doi, Asako, Ohashi, Takuya, Kawago, Mitsumasa, Matsuoka, Naoki, Okamura, Shintaro, Tsujii, Satoru, Akamizu, Takashi

“…Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome associated with large tumors. The high molecular weight IGF2, known as…”
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