Search Results - "Kawahara, Rebeca"

A targeted proteomic strategy for the measurement of oral cancer candidate biomarkers in human saliva by Kawahara, Rebeca, Bollinger, James G., Rivera, César, Ribeiro, Ana Carolina P., Brandão, Thaís Bianca, Leme, Adriana F. Paes, MacCoss, Michael J.

“…Head and neck cancers, including oral squamous cell carcinoma (OSCC), are the sixth most common malignancy in the world and are characterized by poor prognosis…”
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Distinct urinary glycoprotein signatures in prostate cancer patients by Kawahara, Rebeca, Ortega, Fabio, Rosa-Fernandes, Livia, Guimarães, Vanessa, Quina, Daniel, Nahas, Willian, Schwämmle, Veit, Srougi, Miguel, Leite, Katia R M, Thaysen-Andersen, Morten, Larsen, Martin R, Palmisano, Giuseppe

“…Novel biomarkers are needed to complement prostate specific antigen (PSA) in prostate cancer (PCa) diagnostic screening programs. Glycoproteins represent a…”
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Quantitative proteomic analysis of amastigotes from Leishmania (L.) amazonensis LV79 and PH8 strains reveals molecular traits associated with the virulence phenotype by de Rezende, Eloiza, Kawahara, Rebeca, Peña, Mauricio S, Palmisano, Giuseppe, Stolf, Beatriz S

“…Leishmaniasis is an antropozoonosis caused by Leishmania parasites that affects around 12 million people in 98 different countries. The disease has different…”
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Zika Virus Impairs Neurogenesis and Synaptogenesis Pathways in Human Neural Stem Cells and Neurons by Rosa-Fernandes, Livia, Cugola, Fernanda Rodrigues, Russo, Fabiele Baldino, Kawahara, Rebeca, de Melo Freire, Caio Cesar, Leite, Paulo Emílio Corrêa, Bassi Stern, Ana Carolina, Angeli, Claudia Blanes, de Oliveira, Danielle Bruna Leal, Melo, Stella Rezende, Zanotto, Paolo Marinho de Andrade, Durigon, Edison Luiz, Larsen, Martin Røssel, Beltrão-Braga, Patricia Cristina Baleeiro, Palmisano, Giuseppe

“…Growing evidences have associated Zika virus (ZIKV) infection with congenital malformations, including microcephaly. Nonetheless, signaling mechanisms that…”
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Profound N -glycan remodelling accompanies MHC-II immunopeptide presentation by Goodson, Hayley, Kawahara, Rebeca, Chatterjee, Sayantani, Goncalves, Gabriel, Fehring, Joshua, Purcell, Anthony W, Croft, Nathan P, Thaysen-Andersen, Morten

“…Immunopeptidomics, the study of peptide antigens presented on the cell surface by the major histocompatibility complex (MHC), offers insights into how our…”
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Analysis of the Salivary Gland Transcriptome of Unfed and Partially Fed Amblyomma sculptum Ticks and Descriptive Proteome of the Saliva by Esteves, Eliane, Maruyama, Sandra R, Kawahara, Rebeca, Fujita, André, Martins, Larissa A, Righi, Adne A, Costa, Francisco B, Palmisano, Giuseppe, Labruna, Marcelo B, Sá-Nunes, Anderson, Ribeiro, José M C, Fogaça, Andréa C

“…Ticks are obligate blood feeding ectoparasites that transmit a wide variety of pathogenic microorganisms to their vertebrate hosts. is vector of , the…”
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Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate by Kawahara, Rebeca, Granato, Daniela Campos, Yokoo, Sami, Domingues, Romênia Ramos, Trindade, Daniel Maragno, Paes Leme, Adriana Franco

“…ADAM17 (a disintegrin and metalloproteinase 17) is a plasma membrane metalloprotease involved in proteolytic release of the extracellular domain of many cell…”
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Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma by Kawahara, Rebeca, Granato, Daniela C, Carnielli, Carolina M, Cervigne, Nilva K, Oliveria, Carine E, Rivera, César, Martinez, César A R, Yokoo, Sami, Fonseca, Felipe P, Lopes, Marcio, Santos-Silva, Alan R, Graner, Edgard, Coletta, Ricardo D, Paes Leme, Adriana Franco

“…Oral squamous cell carcinoma is the most common type of cancer in the oral cavity, representing more than 90% of all oral cancers. The characterization of…”
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The intracellular bacterium Rickettsia rickettsii exerts an inhibitory effect on the apoptosis of tick cells by Martins, Larissa Almeida, Palmisano, Giuseppe, Cortez, Mauro, Kawahara, Rebeca, de Freitas Balanco, José Mario, Fujita, André, Alonso, Beatriz Iglesias, Barros-Battesti, Darci Moraes, Braz, Gloria Regina Cardoso, Tirloni, Lucas, Esteves, Eliane, Daffre, Sirlei, Fogaça, Andréa Cristina

“…Abstract Background Rickettsia rickettsii is a tick-borne obligate intracellular bacterium that causes Rocky Mountain spotted fever, a life-threatening…”
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Deciphering the Role of the ADAM17-Dependent Secretome in Cell Signaling by Kawahara, Rebeca, Lima, Renato Niyama, Domingues, Romênia R, Pauletti, Bianca Alves, Meirelles, Gabriela V, Assis, Michelle, Figueira, Ana Carolina Migliorini, Leme, Adriana Franco Paes

“…ADAM17 has been initially identified as the main sheddase responsible for releasing the soluble form of a variety of cell-surface proteins, including growth…”
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Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2) by de Oliveira, Gilberto Santos, Kawahara, Rebeca, Rosa-Fernandes, Livia, Mule, Simon Ngao, Avila, Carla Cristi, Teixeira, Marta M G, Larsen, Martin R, Palmisano, Giuseppe

“…Chagas disease also known as American trypanosomiasis is caused by the protozoan Trypanosoma cruzi. Over the last 30 years, Chagas disease has expanded from a…”
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Novel processed form of syndecan-1 shed from SCC-9 cells plays a role in cell migration by Aragão, Annelize Z B, Belloni, Marília, Simabuco, Fernando M, Zanetti, Mariana R, Yokoo, Sami, Domingues, Romênia R, Kawahara, Rebeca, Pauletti, Bianca A, Gonçalves, Anderson, Agostini, Michelle, Graner, Edgard, Coletta, Ricardo D, Fox, Jay W, Paes Leme, Adriana F

“…The extracellular milieu is comprised in part by products of cellular secretion and cell surface shedding. The presence of such molecules of the sheddome and…”
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ADAM17 cytoplasmic domain modulates Thioredoxin-1 conformation and activity by e Costa, Rute A.P., Granato, Daniela C., Trino, Luciana D., Yokoo, Sami, Carnielli, Carolina M., Kawahara, Rebeca, Domingues, Romênia R., Pauletti, Bianca Alves, Neves, Leandro Xavier, Santana, Aline G., Paulo, Joao A., Aragão, Annelize Z.B., Heleno Batista, Fernanda Aparecida, Migliorini Figueira, Ana Carolina, Laurindo, Francisco R.M., Fernandes, Denise, Hansen, Hinrich P., Squina, Fabio, Gygi, Steven P., Paes Leme, Adriana F.

“…The activity of Thioredoxin-1 (Trx-1) is adjusted by the balance of its monomeric, active and its dimeric, inactive state. The regulation of this balance is…”
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Towards structure-focused glycoproteomics by Chernykh, Anastasia, Kawahara, Rebeca, Thaysen-Andersen, Morten

“…Facilitated by advances in the separation sciences, mass spectrometry and informatics, glycoproteomics, the analysis of intact glycopeptides at scale, has…”
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Critical considerations in N-glycoproteomics by Chau, The Huong, Chernykh, Anastasia, Kawahara, Rebeca, Thaysen-Andersen, Morten

“…N-Glycoproteomics, the system-wide study of glycans asparagine-linked to protein carriers, holds a unique and still largely untapped potential to provide deep…”
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The Complexity and Dynamics of the Tissue Glycoproteome Associated With Prostate Cancer Progression by Kawahara, Rebeca, Recuero, Saulo, Srougi, Miguel, Leite, Katia R.M., Thaysen-Andersen, Morten, Palmisano, Giuseppe

“…The complexity and dynamics of the immensely heterogeneous glycoproteome of the prostate cancer (PCa) tumor microenvironment remain incompletely mapped, a…”
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α-Mannosylated HLA-II glycopeptide antigens dominate the immunopeptidome of immortalised cells and tumour tissues by Goodson, Hayley, Kawahara, Rebeca, Fehring, Joshua, Purcell, Anthony W, Croft, Nathan P, Thaysen-Andersen, Morten

“…Immunopeptides are cell surface-located protein fragments that aid our immune system to recognise and respond to pathogenic insult and malignant…”
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N-acetyl-β-D-hexosaminidases mediate the generation of paucimannosidic proteins via a putative noncanonical truncation pathway in human neutrophils by Ugonotti, Julian, Kawahara, Rebeca, Loke, Ian, Zhu, Yuqi, Chatterjee, Sayantani, Tjondro, Harry C, Sumer-Bayraktar, Zeynep, Neelamegham, Sriram, Thaysen-Andersen, Morten

“…Abstract We recently discovered that human neutrophils express immunomodulatory glycoproteins carrying unusual and highly truncated paucimannosidic N-glycans…”
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Trends in oligomannosylation and α1,2-mannosidase expression in human cancers by Chatterjee, Sayantani, Ugonotti, Julian, Lee, Ling Y., Everest-Dass, Arun, Kawahara, Rebeca, Thaysen-Andersen, Morten

“…Aberrant protein glycosylation is a prominent cancer feature. While many tumour-associated glycoepitopes have been reported, advances in glycoanalytics…”
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Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells by Parker, Robert, Partridge, Thomas, Wormald, Catherine, Kawahara, Rebeca, Stalls, Victoria, Aggelakopoulou, Maria, Parker, Jimmy, Powell Doherty, Rebecca, Ariosa Morejon, Yoanna, Lee, Esther, Saunders, Kevin, Haynes, Barton F., Acharya, Priyamvada, Thaysen-Andersen, Morten, Borrow, Persephone, Ternette, Nicola

“…Understanding and eliciting protective immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an urgent priority. To facilitate…”
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