Search Results - "Kawaguchi, Yoshirou"

Ionic Liquid-Based Immunization Patch for the Transdermal Delivery of Antigens by Islam, Rashedul, Nabila, Fahmida Habib, Wakabayashi, Rie, Kawaguchi, Yoshirou, Kamiya, Noriho, Moniruzzaman, Muhammad, Goto, Masahiro

“…Herein, we report a transdermal patch prepared using an ionic liquid-based solid in oil (IL-S/O) nanodispersion and a pressure-sensitive adhesive (PSA) to…”
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Discovery of potent and specific inhibitors targeting the active site of MMP-9 from the engineered SPINK2 library by Yano, Hidenori, Nishimiya, Daisuke, Kawaguchi, Yoshirou, Tamura, Masakazu, Hashimoto, Ryuji

“…Matrix metalloproteinases (MMPs) contribute to many physiological and pathological phenomena via the proteolysis of extracellular matrix components. Specific…”
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Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification by Iwamoto, Mitsuhiro, Sekiguchi, Yukiko, Nakamura, Kensuke, Kawaguchi, Yoshirou, Honda, Takeshi, Hasegawa, Jun

“…The fine structures of Fc N-glycan modulate the biological functions and physicochemical properties of antibodies. By remodeling N-glycan to obtain a…”
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Crystal structure of human tyrosylprotein sulfotransferase-2 reveals the mechanism of protein tyrosine sulfation reaction by Teramoto, Takamasa, Fujikawa, Yukari, Kawaguchi, Yoshirou, Kurogi, Katsuhisa, Soejima, Masayuki, Adachi, Rumi, Nakanishi, Yuichi, Mishiro-Sato, Emi, Liu, Ming-Cheh, Sakakibara, Yoichi, Suiko, Masahito, Kimura, Makoto, Kakuta, Yoshimitsu

“…Post-translational protein modification by tyrosine sulfation has an important role in extracellular protein–protein interactions. The protein tyrosine…”
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The crystal structure of novel chondroitin lyase ODV-E66, a baculovirus envelope protein by Kawaguchi, Yoshirou, Sugiura, Nobuo, Kimata, Koji, Kimura, Makoto, Kakuta, Yoshimitsu

“…•The crystal structures of a novel chondroitin lyase from baculovirus was determined.•The structural fold of ODV-E66 resembled that of PL8 family enzymes.•The…”
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Glucuronyltransferase Activity of KfiC from Escherichia coli Strain K5 Requires Association of KfiA by Sugiura, Nobuo, Baba, Yuichi, Kawaguchi, Yoshirou, Iwatani, Toru, Suzuki, Kiyoshi, Kusakabe, Takahiro, Yamagishi, Kiwamu, Kimata, Koji, Kakuta, Yoshimitsu, Watanabe, Hideto

“…Heparan sulfate is a ubiquitous glycosaminoglycan in the extracellular matrix of most animals. It interacts with various molecules and exhibits important…”
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Crystallization and X-ray diffraction analysis of chondroitin lyase from baculovirus: envelope protein ODV-E66 by Kawaguchi, Yoshirou, Sugiura, Nobuo, Onishi, Momo, Kimata, Koji, Kimura, Makoto, Kakuta, Yoshimitu

“…Baculovirus envelope protein ODV‐E66 (67–704), in which the N‐terminal 66 amino acids are truncated, is a chondroitin lyase. It digests chondroitin and…”
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A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases by Nishimiya, Daisuke, Kawaguchi, Yoshirou, Kodama, Shiho, Nasu, Hatsumi, Yano, Hidenori, Yamaguchi, Aya, Tamura, Masakazu, Hashimoto, Ryuji

“…Proteases are one of attractive therapeutic targets to play key roles in pharmacological action. There are many protease inhibitors in nature, and most of them…”
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Glucuronyltransferase activity of KfiC from Escherichia coli strain K5 requires association of KfiA: KfiC and KfiA are essential enzymes for production of K5 polysaccharide, N-acetylheparosan by Sugiura, Nobuo, Baba, Yuichi, Kawaguchi, Yoshirou, Iwatani, Toru, Suzuki, Kiyoshi, Kusakabe, Takahiro, Yamagishi, Kiwamu, Kimata, Koji, Kakuta, Yoshimitsu, Watanabe, Hideto

“…Heparan sulfate is a ubiquitous glycosaminoglycan in the extracellular matrix of most animals. It interacts with various molecules and exhibits important…”
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The crystal structure of novel chondroitin lyase ODV-E66, a baculovirus envelope protein by Kawaguchi, Yoshirou, Sugiura, Nobuo, Kimata, Koji, Kimura, Makoto, Kakuta, Yoshimitu

“…Chondroitin lyases have been known as pathogenic bacterial enzymes that degrade chondroitin. Recently, baculovirus envelope protein ODV-E66 was identified as…”
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