Search Results - "Kavanaugh, Scott"
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Localization and functional characterization of a novel adipokinetic hormone in the mollusk, Aplysia californica
Published in PloS one (27-08-2014)“…Increasing evidence suggests that gonadotropin-releasing hormone (GnRH), corazonin, adipokinetic hormone (AKH), and red pigment-concentrating hormone all share…”
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Functional Authentication of a Novel Gastropod Gonadotropin-Releasing Hormone Receptor Reveals Unusual Features and Evolutionary Insight
Published in PloS one (28-07-2016)“…A gonadotropin-releasing hormone (GnRH)-like molecule was previously identified in a gastropod, Aplysia californica, and named ap-GnRH. In this study, we…”
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Origins of Gonadotropin-Releasing Hormone (GnRH) in Vertebrates: Identification of a Novel GnRH in a Basal Vertebrate, the Sea Lamprey
Published in Endocrinology (Philadelphia) (01-08-2008)“…We cloned a cDNA encoding a novel (GnRH), named lamprey GnRH-II, from the sea lamprey, a basal vertebrate. The deduced amino acid sequence of the newly…”
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The origins of the vertebrate hypothalamic–pituitary–gonadal (HPG) and hypothalamic–pituitary–thyroid (HPT) endocrine systems: New insights from lampreys
Published in General and comparative endocrinology (01-03-2009)“…Abstract The acquisition of a hypothalamic–pituitary axis was a seminal event in vertebrate evolution leading to the neuroendocrine control of many complex…”
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Ancient origins of metazoan gonadotropin-releasing hormone and their receptors revealed by phylogenomic analyses
Published in General and comparative endocrinology (01-08-2016)“…Graphical abstract…”
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Novel FGF8 Mutations Associated with Recessive Holoprosencephaly, Craniofacial Defects, and Hypothalamo-Pituitary Dysfunction
Published in The journal of clinical endocrinology and metabolism (01-10-2011)“…Context: Fibroblast growth factor (FGF) 8 is important for GnRH neuronal development with human mutations resulting in Kallmann syndrome. Murine data suggest a…”
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Gonadotropin-releasing hormone in protostomes: Insights from functional studies on Aplysia californica
Published in General and comparative endocrinology (01-05-2012)“…Highlights ► Novel discoveries on the function of protostomian GnRH were made from Aplysia californica . ► GnRH in A. californica (ap-GnRH) is not a…”
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Localization of a molluscan gonadotropin-releasing hormone in Aplysia californica by in situ hybridization and immunocytochemistry
Published in General and comparative endocrinology (01-01-2014)“…Highlights • The de novo synthesis of ap-GnRH is restricted to the central nervous system. • Pedal and cerebral ganglia are the primary sites of ap-GnRH…”
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Fibroblast growth factor signaling in the developing neuroendocrine hypothalamus
Published in Frontiers in neuroendocrinology (01-01-2011)“…Research Highlights ► FGF signaling is most critical during the fate specification of GnRH neurons. ► FGF signaling maintains the postnatal GnRH system. ►…”
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Molecular Cloning and Pharmacological Characterization of Two Novel GnRH Receptors in the Lamprey (Petromyzon marinus)
Published in Endocrinology (Philadelphia) (01-07-2012)“…This paper reports the identification, expression, binding kinetics, and functional studies of two novel type III lamprey GnRH receptors (lGnRH-R-2 and…”
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Seasonal changes of brain GnRH-I, -II, and -III during the final reproductive period in adult male and female sea lamprey
Published in General and comparative endocrinology (15-01-2011)“…Research highlights ► Lampreys are one of the very few vertebrates that have three hypothalamic GnRHs. ► This is the first report examining changes of GnRH in…”
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Disruption of the Suprachiasmatic Nucleus in Fibroblast Growth Factor Signaling-Deficient Mice
Published in Frontiers in endocrinology (Lausanne) (08-02-2016)“…Fibroblast growth factor (Fgf) 8 is essential for the development of multiple brain regions. Previous studies from our laboratory showed that reduced Fgf8…”
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Fibroblast Growth Factor Signaling Deficiencies Impact Female Reproduction and Kisspeptin Neurons in Mice1
Published in Biology of reproduction (01-04-2012)“…Fibroblast growth factor (FGF) signaling is essential for the development of the gonadotropin-releasing hormone (GnRH) system. Mice harboring deficiencies in…”
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Fibroblast Growth Factor Signaling Deficiencies Impact Female Reproduction and Kisspeptin Neurons in Mice
Published in Biology of reproduction (01-04-2012)“…Fibroblast growth factor (FGF) signaling is essential for the development of the gonadotropin-releasing hormone (GnRH) system. Mice harboring deficiencies in…”
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The presence and distribution of gonadotropin-releasing hormone-liked factor in the central nervous system of the black tiger shrimp, Penaeus monodon
Published in General and comparative endocrinology (01-02-2008)“…Abstract The distribution and presence of gonadotropin-releasing hormone (GnRH) in the central nervous system (CNS) of Penaeus monodon were examined by…”
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Inhibition of Bacterial Peptidoglycan Cytopathy by Retina Pigment Epithelial PGRP2 Amidase
Published in Advances in experimental medicine and biology (2023)“…Peptidoglycan (PGN) recognition protein 2 (PGRP2; N-acetylmuramyl-L-alanine amidase (NAMAA)) activity in corneal epithelial cells is thought to inhibit corneal…”
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Erratum to “The origins of the vertebrate hypothalamic–pituitary–gonadal (HPG) and hypothalamic–pituitary–thyroid (HPT) endocrine systems: New insights from lampreys” [General and Comparative Endocrinology (2009) 161, 20–29]
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The identification and distribution of gonadotropin-releasing hormone-like peptides in the central nervous system and ovary of the giant freshwater prawn, Macrobrachium rosenbergii
Published in Invertebrate neuroscience (01-03-2008)“…In the present study, we demonstrated the existence of GnRH-like peptides in the central nervous system (CNS) and ovary of the giant freshwater prawn,…”
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Current Knowledge of Hagfish Reproduction: Implications for Fisheries Management
Published in Integrative and comparative biology (2005)“…This review briefly summarizes the latest findings on reproductive endocrinology of Atlantic hagfish (Myxine glutinosa) and implications for fisheries…”
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Recurrent Annular Peripheral Choroidal Detachment after Trabeculectomy
Published in Case reports in ophthalmology (24-10-2013)“…We report a challenging case of recurrent flat anterior chamber without hypotony after trabeculectomy in a 54-year-old Black male with a remote history of…”
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