Search Results - "Kavanaugh, Jeffrey"

Impact of Environmental Cues on Staphylococcal Quorum Sensing and Biofilm Development by Kavanaugh, Jeffrey S., Horswill, Alexander R.

“…Staphylococci are commensal bacteria that colonize the epithelial surfaces of humans and many other mammals. These bacteria can also attach to implanted…”
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Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus by Kiedrowski, Megan R, Kavanaugh, Jeffrey S, Malone, Cheryl L, Mootz, Joe M, Voyich, Jovanka M, Smeltzer, Mark S, Bayles, Kenneth W, Horswill, Alexander R

“…Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emerging contributor to biofilm-related infections. We recently reported that…”
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Peptide Signaling in the Staphylococci by Thoendel, Matthew, Kavanaugh, Jeffrey S, Flack, Caralyn E, Horswill, Alexander R

“…One of the more intriguing classes of peptide signals are the cyclic lactones and thiolactones. The first of these cyclic peptide signals was discovered in…”
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Staphylococcus epidermidis protease EcpA can be a deleterious component of the skin microbiome in atopic dermatitis by Cau, Laura, Williams, Michael R., Butcher, Anna M., Nakatsuji, Teruaki, Kavanaugh, Jeffrey S., Cheng, Joyce Y., Shafiq, Faiza, Higbee, Kyle, Hata, Tissa R., Horswill, Alexander R., Gallo, Richard L.

“…Staphylococcus aureus and Staphylococcus epidermidis are the most abundant bacteria found on the skin of patients with atopic dermatitis (AD). S aureus is…”
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Identification of Extracellular DNA-Binding Proteins in the Biofilm Matrix by Kavanaugh, Jeffrey S, Flack, Caralyn E, Lister, Jessica, Ricker, Erica B, Ibberson, Carolyn B, Jenul, Christian, Moormeier, Derek E, Delmain, Elizabeth A, Bayles, Kenneth W, Horswill, Alexander R

“…We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial…”
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Cathepsin G Degrades Staphylococcus aureus Biofilms by Kavanaugh, Jeffrey S, Leidal, Kevin G, Nauseef, William M, Horswill, Alexander R

“…Abstract Polymorphonuclear leukocytes (PMN) phagocytose and kill individual bacteria but are far less efficient when challenged with bacterial aggregates…”
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Lipoproteins from Staphylococcus aureus Drive Neutrophil Extracellular Trap Formation in a TLR2/1- and PAD-Dependent Manner by Hook, Jessica S, Patel, Parth A, O'Malley, Aidan, Xie, Lihua, Kavanaugh, Jeffrey S, Horswill, Alexander R, Moreland, Jessica G

“…Neutrophils, polymorphonuclear leukocytes (PMN), play a critical role in the innate immune response to , a pathogen that continues to be associated with…”
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Estimating Temperature Fields from MODIS Land Surface Temperature and Air Temperature Observations in a Sub-Arctic Alpine Environment by Williamson, Scott N, Hik, David S, Gamon, John A, Kavanaugh, Jeffrey L, Flowers, Gwenn E

“…Spatially continuous satellite infrared temperature measurements are essential for understanding the consequences and drivers of change, at local and regional…”
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Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense by Parlet, Corey P., Kavanaugh, Jeffrey S., Crosby, Heidi A., Raja, Huzefa A., El-Elimat, Tamam, Todd, Daniel A., Pearce, Cedric J., Cech, Nadja B., Oberlies, Nicholas H., Horswill, Alexander R.

“…Recurrent epidemics of drug-resistant Staphylococcus aureus illustrate the rapid lapse of antibiotic efficacy following clinical implementation. Over the last…”
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Polyhydroxyanthraquinones as Quorum Sensing Inhibitors from the Guttates of Penicillium restrictum and Their Analysis by Desorption Electrospray Ionization Mass Spectrometry by Figueroa, Mario, Jarmusch, Alan K, Raja, Huzefa A, El-Elimat, Tamam, Kavanaugh, Jeffrey S, Horswill, Alexander R, Cooks, R. Graham, Cech, Nadja B, Oberlies, Nicholas H

“…The endophytic fungus Penicillium restrictum was isolated from the stems of a milk thistle (Silybum marianum) plant. In culture, the fungus produced distinct…”
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ω-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation by Daly, Seth M, Elmore, Bradley O, Kavanaugh, Jeffrey S, Triplett, Kathleen D, Figueroa, Mario, Raja, Huzefa A, El-Elimat, Tamam, Crosby, Heidi A, Femling, Jon K, Cech, Nadja B, Horswill, Alexander R, Oberlies, Nicholas H, Hall, Pamela R

“…Antibiotic-resistant pathogens are a global health threat. Small molecules that inhibit bacterial virulence have been suggested as alternatives or adjuncts to…”
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Evaluating Cloud Contamination in Clear-Sky MODIS Terra Daytime Land Surface Temperatures Using Ground-Based Meteorology Station Observations by WILLIAMSON, Scott N, HIK, David S, GAMON, John A, KAVANAUGH, Jeffrey L, KOH, Saewan

“…Abstract Environment Canada meteorological station hourly sampled air temperatures Tair at four stations in the southwest Yukon were used to identify cloud…”
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Staphylococcus aureus Nuclease Is an SaeRS-Dependent Virulence Factor by Olson, Michael E, Nygaard, Tyler K, Ackermann, Laynez, Watkins, Robert L, Zurek, Oliwia W, Pallister, Kyler B, Griffith, Shannon, Kiedrowski, Megan R, Flack, Caralyn E, Kavanaugh, Jeffrey S, Kreiswirth, Barry N, Horswill, Alexander R, Voyich, Jovanka M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A role for type I signal peptidase in Staphylococcus aureus quorum sensing by Kavanaugh, Jeffrey S., Thoendel, Matthew, Horswill, Alexander R.

“…Summary The Staphylococcus aureus Agr quorum‐sensing system modulates the expression of extracellular virulence factors. The Agr system is controlled by an…”
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Rot is a key regulator of Staphylococcus aureus biofilm formation by Mootz, Joe M., Benson, Meredith A., Heim, Cortney E., Crosby, Heidi A., Kavanaugh, Jeffrey S., Dunman, Paul M., Kielian, Tammy, Torres, Victor J., Horswill, Alexander R.

“…Summary Staphylococcus aureus is a significant cause of chronic biofilm infections on medical implants. We investigated the biofilm regulatory cascade and…”
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Role for IRAK-4 and p38 in Neutrophil Signaling in Response to Bacterial Lipoproteins from Staphylococcus aureus by Hook, Jessica S, Matheis, Austin D, Kavanaugh, Jeffrey S, Horswill, Alexander R, Moreland, Jessica G

“…Neutrophils, polymorphonuclear leukocytes (PMN), express numerous pattern recognition receptors, including TLRs, capable of recognizing a wide variety of…”
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The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia by Langouët-Astrié, Christophe, Oshima, Kaori, McMurtry, Sarah A., Yang, Yimu, Kwiecinski, Jakub M., LaRivière, Wells B., Kavanaugh, Jeffrey S., Zakharevich, Igor, Hansen, Kirk C., Shi, Deling, Zhang, Fuming, Boguslawski, Kristina M., Perelman, Sofya S., Su, Gouwei, Torres, Victor J., Liu, Jian, Horswill, Alexander R., Schmidt, Eric P.

“…Influenza infection is substantially worsened by the onset of secondary pneumonia caused by bacteria, such as methicillin-resistant Staphylococcus aureus…”
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Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm by de Vor, Lisanne, van Dijk, Bruce, van Kessel, Kok, Kavanaugh, Jeffrey S, de Haas, Carla, Aerts, Piet C, Viveen, Marco C, Boel, Edwin C, Fluit, Ad C, Kwiecinski, Jakub M, Krijger, Gerard C, Ramakers, Ruud M, Beekman, Freek J, Dadachova, Ekaterina, Lam, Marnix Geh, Vogely, H Charles, van der Wal, Bart Ch, van Strijp, Jos Ag, Horswill, Alexander R, Weinans, Harrie, Rooijakkers, Suzan Hm

“…Implant-associated infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host…”
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Truncated Autoinducing Peptides as Antagonists of Staphylococcus lugdunensis Quorum Sensing by Gordon, Christopher P, Olson, Shondra D, Lister, Jessica L, Kavanaugh, Jeffrey S, Horswill, Alexander R

“…Competitive quorum sensing (QS) antagonism offers a novel strategy for attenuating current multidrug resistant staphylococcal infections. To this end, a series…”
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Quorum quenching and antimicrobial activity of goldenseal (Hydrastis canadensis) against methicillin-resistant Staphylococcus aureus (MRSA) by Cech, Nadja B, Junio, Hiyas A, Ackermann, Laynez W, Kavanaugh, Jeffrey S, Horswill, Alexander R

“…The popular herbal remedy goldenseal (Hydrastis canadensis L.) is traditionally used to treat skin infections. With this study, we show activity of H…”
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