Search Results - "Kauss, Ariel"
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Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo
Published in Cytotherapy (Oxford, England) (01-08-2013)“…Abstract Background aims Although recombinant adeno-associated virus serotype 2 (AAV2) vectors have gained attention because of their safety and efficacy in…”
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Journal Article -
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Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation
Published in Experimental cell research (01-10-2008)“…Estrogen receptors are historically perceived as nuclear ligand activated transcription factors. An estrogen receptor has now been found localized to the…”
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Journal Article -
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Enhanced long-term transduction and multilineage engraftment of human hematopoietic stem cells transduced with tyrosine-modified recombinant adeno-associated virus serotype 2
Published in Human gene therapy (01-09-2010)“…The search for the ideal stem cell gene therapy vector continues as recognized problems persist. Although recombinant adeno-associated virus serotype 2 (rAAV2)…”
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Considerations for in vitro systems to reflect in vivo toxicities to facilitate drug development
Published in Journal of pharmacological and toxicological methods (01-09-2016)Get full text
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Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid
Published in Toxicology mechanisms and methods (01-03-2015)“…Abstract Nicotinamide adenine dinucleotide (NAD) is an essential co-factor in glycolysis and is a key molecule involved in maintaining cellular energy…”
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Modeling the Cardiac Extracellular Matrix to Identify Age-Specific Modulators of Cardiomyocyte Function
Published 01-01-2020“…The extracellular matrix (ECM) is a complex network of proteins that surrounds cells in all tissues, providing structural and biochemical cues that influence a…”
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Dissertation -
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