Search Results - "Kaushik, Gaurav"

Targeting Cancer Stem Cells for Chemoprevention of Pancreatic Cancer by Subramaniam, Dharmalingam, Kaushik, Gaurav, Dandawate, Prasad, Anant, Shrikant

“…Pancreatic ductal adenocarcinoma is one of the deadliest cancers worldwide and the fourth leading cause of cancer-related deaths in United States. Regardless…”
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Concise Review: Organ Engineering: Design, Technology, and Integration by Kaushik, Gaurav, Leijten, Jeroen, Khademhosseini, Ali

“…Engineering complex tissues and whole organs has the potential to dramatically impact translational medicine in several avenues. Organ engineering is a…”
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Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy by Angulo, Pablo, Kaushik, Gaurav, Subramaniam, Dharmalingam, Dandawate, Prasad, Neville, Kathleen, Chastain, Katherine, Anant, Shrikant

“…Osteosarcoma is the most common primary bone cancer affecting children and adolescents worldwide. Despite an incidence of three cases per million annually, it…”
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The Cancer Genomics Cloud: Collaborative, Reproducible, and Democratized-A New Paradigm in Large-Scale Computational Research by Lau, Jessica W, Lehnert, Erik, Sethi, Anurag, Malhotra, Raunaq, Kaushik, Gaurav, Onder, Zeynep, Groves-Kirkby, Nick, Mihajlovic, Aleksandar, DiGiovanna, Jack, Srdic, Mladen, Bajcic, Dragan, Radenkovic, Jelena, Mladenovic, Vladimir, Krstanovic, Damir, Arsenijevic, Vladan, Klisic, Djordje, Mitrovic, Milan, Bogicevic, Igor, Kural, Deniz, Davis-Dusenbery, Brandi

“…The Seven Bridges Cancer Genomics Cloud (CGC; www.cancergenomicscloud.org) enables researchers to rapidly access and collaborate on massive public cancer…”
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Germline Chd8 haploinsufficiency alters brain development in mouse by Gompers, Andrea L, Su-Feher, Linda, Ellegood, Jacob, Copping, Nycole A, Riyadh, M Asrafuzzaman, Stradleigh, Tyler W, Pride, Michael C, Schaffler, Melanie D, Wade, A Ayanna, Catta-Preta, Rinaldo, Zdilar, Iva, Louis, Shreya, Kaushik, Gaurav, Mannion, Brandon J, Plajzer-Frick, Ingrid, Afzal, Veena, Visel, Axel, Pennacchio, Len A, Dickel, Diane E, Lerch, Jason P, Crawley, Jacqueline N, Zarbalis, Konstantinos S, Silverman, Jill L, Nord, Alex S

“…Strong genetic evidence points to a significant role for heterozygous mutations to general chromatin remodeling factors, such as CHD8, in autism. Gompers et al…”
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Influence of genetic variability in toll-like receptors (TLR 2, TLR 4, and TLR 9) on human immunodeficiency virus-1 disease progression by Kaushik, Gaurav, Vashishtha, Richa

“…Background: It has been demonstrated that toll-like receptors (TLR2), TLR4, and TLR9 which were initially known for recognizing bacterial products are involved…”
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Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway by Dandawate, Prasad, Subramaniam, Dharmalingam, Panovich, Peyton, Standing, David, Krishnamachary, Balaji, Kaushik, Gaurav, Thomas, Sufi Mary, Dhar, Animesh, Weir, Scott J., Jensen, Roy A., Anant, Shrikant

“…Cancer stem cells (CSCs) have the ability to self-renew and induce drug resistance and recurrence in colorectal cancer (CRC). As current chemotherapy doesn’t…”
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Messenger RNA expression of toll-like receptors (TLR2, TLR4, and TLR9) in HIV-1 infected patients with and without tuberculosis co-infection by Kaushik, Gaurav, Vashishtha, Richa

“…Background: Gene expression levels of TLRs (TLR2, TLR4 and TLR9) are directly involved in the virus recognition and initiation of innate immune responses,…”
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HIV and Sexually Transmitted Infection Testing Among High-Risk Youths: Supporting Positive Opportunities With Teens (SPOT) Youth Center by Plax, Katie, Garbutt, Jane, Kaushik, Gaurav N

“…We investigated the development of and service utilization at Supporting Positive Opportunities with Teens (SPOT)-a community-based health and social service…”
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Direct and Indirect Cost Savings From Sexually Transmitted Infection Testing, Treatment, and Counseling Among Foster Youth by Kennedy, Andrea K., Kaushik, Gaurav, Dubinsky, Emma L., Huseynli, Aytakin, Jonson-Reid, Melissa, Plax, Katie

“…Sexually transmitted infection (STI) prevention programs can decrease the economic burden of STIs. Foster youth have higher rates of STIs compared with their…”
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Beyond autophagy: a novel role for autism-linked Wdfy3 in brain mitophagy by Napoli, Eleonora, Song, Gyu, Panoutsopoulos, Alexios, Riyadh, M. Asrafuzzaman, Kaushik, Gaurav, Halmai, Julian, Levenson, Richard, Zarbalis, Konstantinos S., Giulivi, Cecilia

“…WD repeat and FYVE domain-containing 3 ( WDFY3 ; also known as Autophagy-Linked FYVE or Alfy) is an identified intellectual disability, developmental delay and…”
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Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response by Ramamoorthy, Prabhu, Thomas, Sufi Mary, Kaushik, Gaurav, Subramaniam, Dharmalingam, Chastain, Katherine M, Dhar, Animesh, Tawfik, Ossama, Kasi, Anup, Sun, Weijing, Ramalingam, Satish, Gunewardena, Sumedha, Umar, Shahid, Mammen, Joshua M, Padhye, Subhash B, Weir, Scott J, Jensen, Roy A, Sittampalam, G Sitta, Anant, Shrikant

“…Metastasis is a major cause of cancer-related deaths. A dearth of preclinical models that recapitulate the metastatic microenvironment has impeded the…”
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Laboratory cost analysis of conventional and newer molecular tests for diagnosis of presumptive multidrug-resistant tuberculosis patients by Yadav, Raj, Verma, Ajoy, Kaushik, Gaurav

“…Introduction: Tuberculosis (TB) remains a deadliest infectious disease. Lack of rapid test with low cost is one of the important challenges to eradicate the…”
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Diphenylbutylpiperidine Antipsychotic Drugs Inhibit Prolactin Receptor Signaling to Reduce Growth of Pancreatic Ductal Adenocarcinoma in Mice by Dandawate, Prasad, Kaushik, Gaurav, Ghosh, Chandrayee, Standing, David, Ali Sayed, Afreen Asif, Choudhury, Sonali, Subramaniam, Dharmalingam, Manzardo, Ann, Banerjee, Tuhina, Santra, Santimukul, Ramamoorthy, Prabhu, Butler, Merlin, Padhye, Subhash B., Baranda, Joaquina, Kasi, Anup, Sun, Weijing, Tawfik, Ossama, Coppola, Domenico, Malafa, Mokenge, Umar, Shahid, Soares, Michael J., Saha, Subhrajit, Weir, Scott J., Dhar, Animesh, Jensen, Roy A., Thomas, Sufi Mary, Anant, Shrikant

“…Prolactin (PRL) signaling is up-regulated in hormone-responsive cancers. The PRL receptor (PRLR) is a class I cytokine receptor that signals via the Janus…”
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Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart by Kaushik, Gaurav, Spenlehauer, Alice, Sessions, Ayla O, Trujillo, Adriana S, Fuhrmann, Alexander, Fu, Zongming, Venkatraman, Vidya, Pohl, Danielle, Tuler, Jeremy, Wang, Mingyi, Lakatta, Edward G, Ocorr, Karen, Bodmer, Rolf, Bernstein, Sanford I, Van Eyk, Jennifer E, Cammarato, Anthony, Engler, Adam J

“…The human heart is capable of functioning for decades despite minimal cell turnover or regeneration, suggesting that molecular alterations help sustain heart…”
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Genetic polymorphism of toll-like receptors in HIV-I infected patients with and without tuberculosis co-infection by Kaushik, Gaurav, Vashishtha, Richa, Tripathi, Himanshu, Yadav, Raj

“…Background: Toll-like receptors (TLRs) are identified as one of the key components of innate immune system due to their ability to sense conserved molecular…”
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Platelet-Rich Blood Derivatives for Stem Cell-Based Tissue Engineering and Regeneration by Masoudi, Elham A., Ribas, João, Kaushik, Gaurav, Leijten, Jeroen, Khademhosseini, Ali

“…Platelet-rich blood derivatives have been widely used in different fields of medicine and stem cell-based tissue engineering. They represent natural cocktails…”
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Tumor M2-PK: A novel urine marker of bladder cancer by Liu, Weiya, Woolbright, Benjamin L, Pirani, Karim, Didde, Ryan, Abbott, Erika, Kaushik, Gaurav, Martin, Paige, Hamilton-Reeves, Jill, Taylor, 3rd, John A, Holzbeierlein, Jeffrey M, Anant, Shrikant, Lee, Eugene K

“…Bladder cancer is a "Warburg-like" tumor characterized by a reliance on aerobic glycolysis and expression of pyruvate kinase M2 (PKM2). PKM2 oscillates between…”
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In Situ Mechanical Analysis of Myofibrillar Perturbation and Aging on Soft, Bilayered Drosophila Myocardium by Kaushik, Gaurav, Fuhrmann, Alexander, Cammarato, Anthony, Engler, Adam J.

“…Drosophila melanogaster is a genetically malleable organism with a short life span, making it a tractable system in which to study mechanical effects of…”
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Cancer Vaccines in the Immunotherapy Era: Promise and Potential by Verma, Chaitenya, Pawar, Vishakha Anand, Srivastava, Shivani, Tyagi, Anuradha, Kaushik, Gaurav, Shukla, Surendra Kumar, Kumar, Vinay

“…Therapeutic vaccines are a promising alternative for active immunotherapy for different types of cancers. Therapeutic cancer vaccines aim to prevent immune…”
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