Search Results - "Kaushal, GP"
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Thalidomide protects endothelial cells from doxorubicin‐induced apoptosis but alters cell morphology
Published in Journal of thrombosis and haemostasis (01-02-2004)“…Antiangiogenesis agents are now being used in clinical trials to reduce the risk of recurrence of cancer. Several of these agents, however, are associated with…”
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Prevalence and Clinical Correlates of COVID-19 Outbreak Among Health Care Workers in a Tertiary Level Hospital in Delhi
Published in American journal of infectious diseases (01-02-2021)Get full text
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3
Perinatal Outcome in Overweight Women: An Audit
Published in Curēus (Palo Alto, CA) (31-10-2023)“…BACKGROUNDObesity in pregnancy is associated with a myriad of well-documented complications. However, the outcomes of pregnancy in overweight females, who are…”
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4
Prevalence and Assessment of Factors Associated With Malnutrition in Children Residing in Slums of Mumbai: A Cross-Sectional Study
Published in Curēus (Palo Alto, CA) (19-04-2024)“…Background Malnutrition in children continues to be a serious public health problem in India. Therefore, this study aims to evaluate the prevalence of…”
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p53-dependent Caspase-2 Activation in Mitochondrial Release of Apoptosis-inducing Factor and Its Role in Renal Tubular Epithelial Cell Injury
Published in The Journal of biological chemistry (02-09-2005)“…We demonstrate the role of p53-mediated caspase-2 activation in the mitochondrial release of apoptosis-inducing factor (AIF) in cisplatin-treated renal tubular…”
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6
Apoptotic pathways in ischemic acute renal failure
Published in Kidney international (01-08-2004)“…Apoptotic pathways in ischemic acute renal failure. The study of cell death has emerged as an important and exciting area of research in cell biology. Although…”
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Fibrate prevents cisplatin-induced proximal tubule cell death
Published in Kidney international (01-12-2005)“…Fibrate prevents cisplatin-induced proximal tubule cell death. In previous studies we have shown that cisplatin inhibits peroxisome proliferator-activated…”
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8
Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells
Published in Kidney international (01-11-2001)“…Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells. Cellular and molecular mechanisms responsible for…”
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9
Disruption of renal peritubular blood flow in lipopolysaccharide-induced renal failure: role of nitric oxide and caspases
Published in American journal of physiology. Renal physiology (01-12-2005)“…Acute renal failure (ARF) is a frequent and serious complication of endotoxemia caused by lipopolysaccharide (LPS) and contributes significantly to mortality…”
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10
Generation of biologically active interleukin-1β by meprin B
Published in Cytokine (Philadelphia, Pa.) (07-09-2005)“…Interleukin-1β (IL-1β) is a proinflammatory cytokine that is synthesized as an inactive precursor molecule that must be proteolytically processed to generate…”
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11
The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide
Published in Biochemical pharmacology (01-08-2003)“…Assessment of specific apoptosis and survival pathways implicated in anticancer drug action is important for understanding drug mechanisms and modes of…”
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Apoptotic mechanisms in acute renal failure
Published in The American journal of medicine (01-04-2000)“…It has been generally accepted that a catastrophic breakdown of regulated cellular homeostasis, known as necrosis, is the mode of cellular injury in various…”
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Regulation of caspase-3 and -9 activation in oxidant stress to RTE by forkhead transcription factors, Bcl-2 proteins, and MAP kinases
Published in American journal of physiology. Renal physiology (01-12-2004)“…Cytotoxicity to renal tubular epithelial cells (RTE) is dependent on the relative response of cell survival and cell death signals triggered by the injury…”
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14
Apoptotic pathways of oxidative damage to renal tubular epithelial cells
Published in Antioxidants & redox signaling (01-12-2002)“…Toxic renal failure induced by gentamicin, glycerol, or cisplatin, as well as ischemic renal failure in vivo and hypoxia/reoxygenation of tubular epithelial…”
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15
Role of caspases in renal tubular epithelial cell injury
Published in Seminars in nephrology (01-09-2003)“…The regulation of cell death has been investigated in a number of clinical disorders including renal ischemic and toxic acute renal failure. Caspases play a…”
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16
Onychomycosis in central India: a clinicoetiologic correlation
Published in International journal of dermatology (01-07-2004)“…Background Onychomycosis is mainly caused by dermatophytes, but yeasts and nondermatophyte molds have also been implicated, giving rise to diverse clinical…”
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The new kids on the block: ADAMTSs, potentially multifunctional metalloproteinases of the ADAM family
Published in The Journal of clinical investigation (15-05-2000)Get full text
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Identification of gene family of caspases in rat kidney and altered expression in ischemia-reperfusion injury
Published in The American journal of physiology (01-03-1998)“…In the present study, we demonstrate that rat kidney contains caspase activity that was markedly inhibited by specific peptide inhibitors of caspases but not…”
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Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium
Published in Leukemia research (01-05-2004)“…The mechanism of action of alemtuzumab (CAMPATH 1H) in chronic lymphocytic leukemia (CLL) is uncertain. We tested the hypothesis that alemtuzumab alone can…”
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20
DNase I-like endonuclease in rat kidney cortex that is activated during ischemia/reperfusion injury
Published in Journal of the American Society of Nephrology (01-04-2002)“…Ischemia/reperfusion is known to result in DNA fragmentation and cell death in kidney tubular epithelium, but the endonucleases responsible for this DNA damage…”
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