Search Results - "Kaurov, Iosif"
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The Diverged Trypanosome MICOS Complex as a Hub for Mitochondrial Cristae Shaping and Protein Import
Published in Current biology (05-11-2018)“…The mitochondrial contact site and cristae organization system (MICOS) is a multiprotein complex responsible for cristae formation. Even though cristae are…”
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The essential cysteines in the CIPC motif of the thioredoxin-like Trypanosoma brucei MICOS subunit TbMic20 do not form an intramolecular disulfide bridge in vivo
Published in Molecular and biochemical parasitology (01-03-2022)“…The mitochondrial protein import machinery of trypanosomatids is highly divergent from that of the well-studied models such as baker’s yeast. A notable example…”
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The highly diverged trypanosomal MICOS complex is organized in a nonessential integral membrane and an essential peripheral module
Published in Molecular microbiology (01-12-2019)“…Summary The mitochondrial contact site and cristae organization system (MICOS) mediates the formation of cristae, invaginations in the mitochondrial inner…”
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Trypanosomatid mitochondrial RNA editing: dramatically complex transcript repertoires revealed with a dedicated mapping tool
Published in Nucleic acids research (25-01-2018)“…Abstract RNA editing by targeted insertion and deletion of uridine is crucial to generate translatable mRNAs from the cryptogenes of the mitochondrial genome…”
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