Search Results - "Kaufmanova, Jirina"
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Diagnosing Czech Patients with Inherited Platelet Disorders
Published in International journal of molecular sciences (19-11-2022)“…A single-center study was conducted on 120 patients with inherited disorders of primary hemostasis followed at our hematological center. These patients…”
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Fibrin Clot Formation under Oxidative Stress Conditions
Published in Antioxidants (07-06-2021)“…During coagulation, the soluble fibrinogen is converted into insoluble fibrin. Fibrinogen is a multifunctional plasma protein, which is essential for…”
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Impact of posttranslational modifications on atomistic structure of fibrinogen
Published in PloS one (29-01-2020)“…Oxidative stress in humans is related to various pathophysiological processes, which can manifest in numerous diseases including cancer, cardiovascular…”
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Mechanical, corrosion and biological properties of advanced biodegradable Mg–MgF2 and WE43-MgF2 composite materials prepared by spark plasma sintering
Published in Journal of alloys and compounds (05-06-2020)“…Newly developed magnesium composite materials with a continuous network of MgF2 prepared by powder metallurgy exerted enhanced corrosion resistance and seems…”
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Impact of Genetic and Post-Translational Modifications on Structure and Function of Fibrinogen
Published in Blood (15-11-2022)Get full text
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Molecular and Clinical Aspects of Aα Dysfibrinogenemia in 25 Patients from the Czech Republic
Published in Blood (29-11-2018)“…Fibrinogen is a 340 kDA glycoprotein that plays a vital role in the hemostasis. The three pairs of polypeptide chains (Aα, Bβ and γ) form a heterodimer…”
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Oxidative Modified Fibrinogen in Cardiovascular Diseases
Published in Blood (29-11-2018)“…Background Cardiovascular diseases are linked with oxidative stress which is the source of reactive oxidative and nitrative species, contributors of…”
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Structural and Functional Characterization of Four Novel Fibrinogen Mutations in FGB Causing Congenital Fibrinogen Disorder
Published in International journal of molecular sciences (10-01-2022)“…Congenital fibrinogen disorders are caused by mutations in genes coding for fibrinogen and may lead to various clinical phenotypes. Here, we present a…”
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Thrombosis-associated hypofibrinogenemia: novel abnormal fibrinogen variant FGG c.8G>A with oxidative posttranslational modifications
Published in Blood coagulation & fibrinolysis (01-06-2022)“…Here, we present the first case of fibrinogen variant FGG c.8G>A. We investigated the behaviour of this mutated fibrinogen in blood coagulation using fibrin…”
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Thrombosis-associated hypofibrinogenemia: novel abnormal fibrinogen variant FGG c.8G>A with oxidative posttranslational modifications
Published in Blood coagulation & fibrinolysis (21-01-2022)“…Here, we present the first case of fibrinogen variant FGG c.8G>A. We investigated the behaviour of this mutated fibrinogen in blood coagulation using fibrin…”
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