Search Results - "Kaufmann, Timothy"

Pseudoprogression, radionecrosis, inflammation or true tumor progression? challenges associated with glioblastoma response assessment in an evolving therapeutic landscape by Ellingson, Benjamin M., Chung, Caroline, Pope, Whitney B., Boxerman, Jerrold L., Kaufmann, Timothy J.

“…The wide variety of treatment options that exist for glioblastoma, including surgery, ionizing radiation, anti-neoplastic chemotherapies, anti-angiogenic…”
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Is the blood-brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data by Sarkaria, Jann N, Hu, Leland S, Parney, Ian F, Pafundi, Deanna H, Brinkmann, Debra H, Laack, Nadia N, Giannini, Caterina, Burns, Terence C, Kizilbash, Sani H, Laramy, Janice K, Swanson, Kristin R, Kaufmann, Timothy J, Brown, Paul D, Agar, Nathalie Y R, Galanis, Evanthia, Buckner, Jan C, Elmquist, William F

“…The blood-brain barrier (BBB) excludes the vast majority of cancer therapeutics from normal brain. However, the importance of the BBB in limiting drug delivery…”
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Cerebrospinal fluid drainage complications during first stage and completion fenestrated-branched endovascular aortic repair by Kärkkäinen, Jussi M., Cirillo-Penn, Nolan C., Sen, Indrani, Tenorio, Emanuel R., Mauermann, William J., Gilkey, George D., Kaufmann, Timothy J., Oderich, Gustavo S.

“…To determine the rates and risk factors of complications related to cerebrospinal fluid drainage (CSFD) during first stage and completion fenestrated-branched…”
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A new study in contrasts: brain MRI for the depiction of tumor metabolism by Kaufmann, Timothy J

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Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases by Kaufmann, Timothy J, Smits, Marion, Boxerman, Jerrold, Huang, Raymond, Barboriak, Daniel P, Weller, Michael, Chung, Caroline, Tsien, Christina, Brown, Paul D, Shankar, Lalitha, Galanis, Evanthia, Gerstner, Elizabeth, van den Bent, Martin J, Burns, Terry C, Parney, Ian F, Dunn, Gavin, Brastianos, Priscilla K, Lin, Nancy U, Wen, Patrick Y, Ellingson, Benjamin M

“…Abstract A recent meeting was held on March 22, 2019, among the FDA, clinical scientists, pharmaceutical and biotech companies, clinical trials cooperative…”
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2016 Updates to the WHO Brain Tumor Classification System: What the Radiologist Needs to Know by Johnson, Derek R, Guerin, Julie B, Giannini, Caterina, Morris, Jonathan M, Eckel, Lawrence J, Kaufmann, Timothy J

“…Radiologists play a key role in brain tumor diagnosis and management and must stay abreast of developments in the field to advance patient care and communicate…”
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Discriminating long myelitis of neuromyelitis optica from sarcoidosis by Flanagan, Eoin P., Kaufmann, Timothy J., Krecke, Karl N., Aksamit, Allen J., Pittock, Sean J., Keegan, B. Mark, Giannini, Caterina, Weinshenker, Brian G.

“…Objective To compare longitudinally extensive myelitis in neuromyelitis optica spectrum disorders (NMOSD) and spinal cord sarcoidosis (SCS). Methods We…”
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Consensus recommendations for MRI and PET imaging of primary central nervous system lymphoma: guideline statement from the International Primary CNS Lymphoma Collaborative Group (IPCG) by Barajas, Ramon F, Politi, Letterio S, Anzalone, Nicoletta, Schöder, Heiko, Fox, Christopher P, Boxerman, Jerrold L, Kaufmann, Timothy J, Quarles, C Chad, Ellingson, Benjamin M, Auer, Dorothee, Andronesi, Ovidiu C, Ferreri, Andres J M, Mrugala, Maciej M, Grommes, Christian, Neuwelt, Edward A, Ambady, Prakash, Rubenstein, James L, Illerhaus, Gerald, Nagane, Motoo, Batchelor, Tracy T, Hu, Leland S

“…Abstract Advanced molecular and pathophysiologic characterization of primary central nervous system lymphoma (PCNSL) has revealed insights into promising…”
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Characteristics of Spontaneous Spinal Cord Infarction and Proposed Diagnostic Criteria by Zalewski, Nicholas L, Rabinstein, Alejandro A, Krecke, Karl N, Brown, Jr, Robert D, Wijdicks, Eelco F M, Weinshenker, Brian G, Kaufmann, Timothy J, Morris, Jonathan M, Aksamit, Allen J, Bartleson, J D, Lanzino, Giuseppe, Blessing, Melissa M, Flanagan, Eoin P

“…Spinal cord infarction (SCI) is often disabling, and the diagnosis can be challenging without an inciting event (eg, aortic surgery). Patients with a…”
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There is an exception to every rule—T2-FLAIR mismatch sign in gliomas by Johnson, Derek R., Kaufmann, Timothy J., Patel, Sohil H., Chi, Andrew S., Snuderl, Matija, Jain, Rajan

“…The T2-FLAIR mismatch sign, in which a low-grade glioma is hyperintense on T2-weighted MR and centrally hypointense on T2-weighted FLAIR MR, has been reported…”
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A Radiologist's Guide to the 2021 WHO Central Nervous System Tumor Classification: Part I-Key Concepts and the Spectrum of Diffuse Gliomas by Johnson, Derek R, Giannini, Caterina, Vaubel, Rachael A, Morris, Jonathan M, Eckel, Laurence J, Kaufmann, Timothy J, Guerin, Julie B

“…The fifth edition of the World Health Organization (WHO) classification of tumors of the central nervous system, published in 2021, contains substantial…”
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Recurrent papillary craniopharyngioma with BRAF V600E mutation treated with dabrafenib: case report by Himes, Benjamin T, Ruff, Michael W, Van Gompel, Jaimie J, Park, Sean S, Galanis, Evanthia, Kaufmann, Timothy J, Uhm, Joon H

“…The authors present the case of a man with a papillary craniopharyngioma, first diagnosed at 47 years of age, who experienced multiple recurrences. Review of…”
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Spinal Cord Ependymomas With MYCN Amplification Show Aggressive Clinical Behavior by Swanson, Amy A, Raghunathan, Aditya, Jenkins, Robert B, Messing-Jünger, Martina, Pietsch, Torsten, Clarke, Michelle J, Kaufmann, Timothy J, Giannini, Caterina

“…Adult spinal cord ependymomas are typically low grade and have a relatively favorable clinical course following gross total resection. We report 4 cases of…”
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Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young by Johnson, Derek R., Giannini, Caterina, Jenkins, Robert B., Kim, Dong Kun, Kaufmann, Timothy J.

“…Purpose Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently described epileptogenic neoplasm. As the name implies, PLNTYs are…”
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BPNSTs: In the eye of the beholder by Kaufmann, Timothy J, Erickson, Bradley J

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A Radiologist's Guide to the 2021 WHO Central Nervous System Tumor Classification: Part 2-Newly Described and Revised Tumor Types by Guerin, Julie B, Kaufmann, Timothy J, Eckel, Laurence J, Morris, Jonathan M, Vaubel, Rachael A, Giannini, Caterina, Johnson, Derek R

“…The fifth edition of the World Health Organization classification of tumors of the central nervous system (CNS), published in 2021, introduces major shifts in…”
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Unique Gadolinium Enhancement Pattern in Spinal Dural Arteriovenous Fistulas by Zalewski, Nicholas L, Rabinstein, Alejandro A, Brinjikji, Waleed, Kaufmann, Timothy J, Nasr, Deena, Ruff, Michael W, Flanagan, Eoin P

“…Spinal dural arteriovenous fistula (sDAVF) is often misdiagnosed as an inflammatory or a neoplastic myelopathy, often because of intraparenchymal gadolinium…”
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Laser ablation for mesial temporal epilepsy: a multi-site, single institutional series by Grewal, Sanjeet S, Zimmerman, Richard S, Worrell, Gregory, Brinkmann, Benjamin H, Tatum, William O, Crepeau, Amy Z, Woodrum, David A, Gorny, Krzysztof R, Felmlee, Joel P, Watson, Robert E, Hoxworth, Joseph M, Gupta, Vivek, Vibhute, Prasanna, Trenerry, Max R, Kaufmann, Timothy J, Marsh, W Richard, Wharen, Robert E, Van Gompel, Jamie J

“…Although it is still early in its application, laser interstitial thermal therapy (LiTT) has increasingly been employed as a surgical option for patients with…”
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A phase 1 and randomized, placebo‐controlled phase 2 trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma: Alliance/North Central Cancer Treatment Group N0872 by Galanis, Evanthia, Anderson, S. Keith, Twohy, Erin L., Carrero, Xiomara W., Dixon, Jesse G., Tran, David Dinh, Jeyapalan, Suriya A., Anderson, Daniel M., Kaufmann, Timothy J., Feathers, Ryan W., Giannini, Caterina, Buckner, Jan C., Anastasiadis, Panos Z., Schiff, David

“…Background Src signaling is markedly upregulated in patients with invasive glioblastoma (GBM) after the administration of bevacizumab. The Src family kinase…”
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BRAF–MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas by Brastianos, Priscilla K., Twohy, Erin, Geyer, Susan, Gerstner, Elizabeth R., Kaufmann, Timothy J., Tabrizi, Shervin, Kabat, Brian, Thierauf, Julia, Ruff, Michael W., Bota, Daniela A., Reardon, David A., Cohen, Adam L., De La Fuente, Macarena I., Lesser, Glenn J., Campian, Jian, Agarwalla, Pankaj K., Kumthekar, Priya, Mann, Bhupinder, Vora, Shivangi, Knopp, Michael, Iafrate, A. John, Curry, William T., Cahill, Daniel P., Shih, Helen A., Brown, Paul D., Santagata, Sandro, Barker, Fred G., Galanis, Evanthia

“…Genetic analysis has shown the presence of activating BRAF mutations in 94% of papillary craniopharyngiomas. A phase 2 study showed partial response or better…”
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