Search Results - "Kaufmann, Tim A. S"

Fluid‐structure interaction of a pulsatile flow with an aortic valve model: A combined experimental and numerical study by Sigüenza, Julien, Pott, Desiree, Mendez, Simon, Sonntag, Simon J., Kaufmann, Tim A.S., Steinseifer, Ulrich, Nicoud, Franck

“…The complex fluid‐structure interaction problem associated with the flow of blood through a heart valve with flexible leaflets is investigated both…”
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Optimizing cerebral perfusion and hemodynamics during cardiopulmonary bypass through cannula design combining in silico, in vitro and in vivo input by Hugenroth, Kristin, Borchardt, Ralf, Ritter, Philine, Groß-Hardt, Sascha, Meyns, Bart, Verbelen, Tom, Steinseifer, Ulrich, Kaufmann, Tim A. S., Engelmann, Ulrich M.

“…Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by…”
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Numerical prediction of thrombus risk in an anatomically dilated left ventricle: the effect of inflow cannula designs by Liao, Sam, Simpson, Benjamin, Neidlin, Michael, Kaufmann, Tim A S, Li, Zhiyong, Woodruff, Maria A, Gregory, Shaun D

“…Implantation of a rotary blood pump (RBP) can cause non-physiological flow fields in the left ventricle (LV) which may trigger thrombosis. Different inflow…”
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Hemodynamic analysis of outflow grafting positions of a ventricular assist device using closed-loop multiscale CFD simulations: Preliminary results by Neidlin, Michael, Corsini, Chiara, Sonntag, Simon J, Schulte-Eistrup, Sebastian, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Pennati, Giancarlo, Kaufmann, Tim A.S

“…Abstract Subclavian arteries are a possible alternate location for left ventricular assist device (LVAD) outflow grafts due to easier surgical access and…”
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In vitro flow investigations in the aortic arch during cardiopulmonary bypass with stereo-PIV by Büsen, Martin, Kaufmann, Tim A.S, Neidlin, Michael, Steinseifer, Ulrich, Sonntag, Simon J

“…Abstract The cardiopulmonary bypass is related to complications like stroke or hypoxia. The cannula jet is suspected to be one reason for these complications,…”
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Implementation of intrinsic lumped parameter modeling into computational fluid dynamics studies of cardiopulmonary bypass by Kaufmann, Tim A.S, Neidlin, Michael, Büsen, Martin, Sonntag, Simon J, Steinseifer, Ulrich

“…Abstract Stroke and cerebral hypoxia are among the main complications during cardiopulmonary bypass (CPB). The two main reasons for these complications are the…”
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A multiscale 0-D/3-D approach to patient-specific adaptation of a cerebral autoregulation model for computational fluid dynamics studies of cardiopulmonary bypass by Neidlin, Michael, Steinseifer, Ulrich, Kaufmann, Tim A.S

“…Abstract Neurological complication often occurs during cardiopulmonary bypass (CPB). One of the main causes is hypoperfusion of the cerebral tissue affected by…”
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Development of a Hemodynamically Optimized Outflow Cannula for Cardiopulmonary Bypass by Kaufmann, Tim A.S., Schlanstein, Peter, Moritz, Anton, Steinseifer, Ulrich

“…The jet of the outflow cannula is a potential risk for patients undergoing cardiopulmonary bypass (CPB), because increased jet velocities lead to altered flow…”
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Response to letter to the editor regarding " In vitro flow investigations in the aortic arch during cardiopulmonary bypass with stereo-PIV" by Büsen, Martin, Kaufmann, Tim A.S, Neidlin, Michael, Steinseifer, Ulrich, Sonntag, Simon J

“…A comparison of our method and the in vivo staining technique could be very promising for further investigation of the cannula flow during cardiopulmonary…”
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Numerical Washout Study of a Pulsatile Total Artificial Heart by Sonntag, Simon J., Kaufmann, Tim A.S., Büsen, Martin R., Laumen, Marco, Gräf, Felix, Linde, Torsten, Steinseifer, Ulrich

“…Purpose For blood pumps with long term indication, blood stagnation can result in excessive thromboembolic risks for patients. This study numerically…”
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Implementation of Cerebral Autoregulation Into Computational Fluid Dynamics Studies of Cardiopulmonary Bypass by Kaufmann, Tim A.S., Schmitz-Rode, Thomas, Steinseifer, Ulrich

“…Peri‐ or postoperative neurological complications are among the main risks for patients undergoing extracorporeal circulatory support (ECC). Two of the main…”
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Analysis of emboli and blood flow in the ophthalmic artery to understand retinal artery occlusion by Kaufmann, Tim A S, Leisser, Christoph, Gemsa, Jeannie, Steinseifer, Ulrich

“…Retinal artery occlusion (RAO) is a common ocular vascular occlusive disorder that may lead to partial or complete retinal ischemia with sudden visual…”
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Mimicking of Cerebral Autoregulation by Flow-Dependent Cerebrovascular Resistance: A Feasibility Study by Kaufmann, Tim A.S., Wong, Kai C., Schmitz-Rode, Thomas, Steinseifer, Ulrich

“…Understanding circulatory autoregulation is essential for improving physiological control of rotary blood pumps and support conditions during cardiopulmonary…”
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Transient, Three-Dimensional Flow Field Simulation through a Mechanical, Trileaflet Heart Valve Prosthesis by Kaufmann, Tim A. S, Linde, Torsten, Cuenca-Navalon, Elena, Schmitz, Christoph, Hormes, Marcus, Schmitz-Rode, Thomas, Steinseifer, Ulrich

“…Thromboembolic complications are one of the major challenges faced by designers and researchers in development of artificial organs with blood-contacting…”
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The Impact of Aortic/Subclavian Outflow Cannulation for Cardiopulmonary Bypass and Cardiac Support: A Computational Fluid Dynamics Study by Kaufmann, Tim A.S., Hormes, Marcus, Laumen, Marco, Timms, Daniel L., Linde, Torsten, Schmitz-Rode, Thomas, Moritz, Anton, Dzemali, Omer, Steinseifer, Ulrich

“…Approximately 100 000 cases of oxygen deficiency in the brain occur during cardiopulmonary bypass (CPB) procedures each year. In particular, perfusion of the…”
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Development of a Numerical Pump Testing Framework by Kaufmann, Tim A.S., Gregory, Shaun D., Büsen, Martin R., Tansley, Geoff D., Steinseifer, Ulrich

“…It has been shown that left ventricular assist devices (LVADs) increase the survival rate in end‐stage heart failure patients. However, there is an ongoing…”
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Tipless transseptal cannula concept combines improved hemodynamic properties and risk‐reduced placement: An in silico proof‐of‐concept by Hugenroth, Kristin, Neidlin, Michael, Engelmann, Ulrich M., Kaufmann, Tim A. S., Steinseifer, Ulrich, Heilmann, Torsten

“…As a leading cause of death worldwide, heart failure is a serious medical condition in which many critically ill patients require temporary mechanical…”
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Crucial Aspects for Using Computational Fluid Dynamics as a Predictive Evaluation Tool for Blood Pumps by Gross-Hardt, Sascha H, Sonntag, Simon J, Boehning, Fiete, Steinseifer, Ulrich, Schmitz-Rode, Thomas, Kaufmann, Tim A.S

“…The suitability of computational fluid dynamics (CFD) as a regulatory tool for safety assessment of medical devices is still limitedA lack of standardized…”
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Design Modifications and Computational Fluid Dynamic Analysis of an Outflow Cannula for Cardiopulmonary Bypass by Neidlin, Michael, Jansen, Sebastian, Moritz, Anton, Steinseifer, Ulrich, Kaufmann, Tim A. S.

“…Cardiopulmonary bypass is a well-established technique during open heart surgeries. However, neurological complications due to insufficient cerebral oxygen…”
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Investigation of hemodynamics during cardiopulmonary bypass: A multiscale multiphysics fluid–structure-interaction study by Neidlin, Michael, Sonntag, Simon J, Schmitz-Rode, Thomas, Steinseifer, Ulrich, Kaufmann, Tim A S

“…Highlights • We develop a numerical framework for flow investigations of cardiopulmonary bypass. • The model uses 3-D FSI and a lumped parameter description of…”
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