Search Results - "Kaufmann, Charles A"

Molecular Triangulation: Bridging Linkage and Molecular-Network Information for Identifying Candidate Genes in Alzheimer's Disease by Krauthammer, Michael, Kaufmann, Charles A., Gilliam, T. Conrad, Rzhetsky, Andrey, Wigler, Michael H.

“…A major challenge in human genetics is identifying the molecular basis of common heritable disorders. In contrast to rare single-gene diseases, multifactorial…”
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Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data by Merritt, Kate, McGuire, Philip K, Egerton, Alice, Aleman, André, Block, Wolfgang, Bloemen, Oswald J N, Borgan, Faith, Bustillo, Juan R, Capizzano, Aristides A, Coughlin, Jennifer Marie, De la Fuente-Sandoval, Camilo, Demjaha, Arsime, Dempster, Kara, Do, Kim Q, Du, Fei, Falkai, Peter, Galinska-Skok, Beata, Gallinat, Jurgen, Gasparovic, Charles, Ginestet, Cedric E, Goto, Naoki, Graff-Guerrero, Ariel, Ho, Beng Choon, Howes, Oliver D, Jauhar, Sameer, Jeon, Peter, Kato, Tadafumi, Kaufmann, Charles A, Kegeles, Lawrence S, Keshavan, Matcheri, Kim, Sang-Young, Kunugi, Hiroshi, Lauriello, John, Liemburg, Edith Jantine, Mcilwain, Meghan E, Modinos, Gemma, Mouchlianitis, Elias D, Nakamura, Jun, Nenadic, Igor, Öngür, Dost, Ota, Miho, Palaniyappan, Lena, Pantelis, Christos, Plitman, Eric, Posporelis, Sotirios, Purdon, Scot E, Reichenbach, Jürgen R, Renshaw, Perry F, Russell, Bruce R, Sawa, Akira, Schaefer, Martin, Shungu, Dikoma C, Smesny, Stefan, Stanley, Jeffrey A, Stone, James M, Szulc, Agata, Taylor, Reggie, Thakkar, Katy, Théberge, Jean, Tibbo, Philip G, van Amelsvoort, Therese, Walecki, Jerzy, Williamson, Peter C, Wood, Stephen James, Xin, Lijing, Yamasue, Hidenori

“…Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered brain glutamatergic function may be associated with the pathophysiology of…”
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Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis by Merritt, Kate, McCutcheon, Robert A., Aleman, André, Ashley, Sarah, Beck, Katherine, Block, Wolfgang, Bloemen, Oswald J. N., Borgan, Faith, Boules, Christiana, Bustillo, Juan R., Capizzano, Aristides A., Coughlin, Jennifer M., David, Anthony, de la Fuente-Sandoval, Camilo, Demjaha, Arsime, Dempster, Kara, Do, Kim Q., Du, Fei, Falkai, Peter, Galińska-Skok, Beata, Gallinat, Jürgen, Gasparovic, Charles, Ginestet, Cedric E., Goto, Naoki, Graff-Guerrero, Ariel, Ho, Beng-Choon, Howes, Oliver, Jauhar, Sameer, Jeon, Peter, Kato, Tadafumi, Kaufmann, Charles A., Kegeles, Lawrence S., Keshavan, Matcheri S., Kim, Sang-Young, King, Bridget, Kunugi, Hiroshi, Lauriello, J., León-Ortiz, Pablo, Liemburg, Edith, Mcilwain, Meghan E., Modinos, Gemma, Mouchlianitis, Elias, Nakamura, Jun, Nenadic, Igor, Öngür, Dost, Ota, Miho, Palaniyappan, Lena, Pantelis, Christos, Patel, Tulsi, Plitman, Eric, Posporelis, Sotirios, Purdon, Scot E., Reichenbach, Jürgen R., Renshaw, Perry F., Reyes-Madrigal, Francisco, Russell, Bruce R., Sawa, Akira, Schaefer, Martin, Shungu, Dikoma C., Smesny, Stefan, Stanley, Jeffrey A., Stone, James, Szulc, Agata, Taylor, Reggie, Thakkar, Katharine N., Théberge, Jean, Tibbo, Philip G., van Amelsvoort, Thérèse, Walecki, Jerzy, Williamson, Peter C., Wood, Stephen J., Xin, Lijing, Yamasue, Hidenori, McGuire, Philip, Egerton, Alice

“…Glutamatergic dysfunction is implicated in schizophrenia pathoaetiology, but this may vary in extent between patients. It is unclear whether inter-individual…”
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Evidence for the multigenic inheritance of schizophrenia by Freedman, Robert, Leonard, Sherry, Olincy, Ann, Kaufmann, Charles A., Malaspina, Dolores, Cloninger, C. Robert, Svrakic, Dragan, Faraone, Stephen V., Tsuang, Ming T.

“…Schizophrenia is assumed to have complex inheritance because of its high prevalence and sporadic familial transmission. Findings of linkage on different…”
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Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies by Kegeles, Lawrence S, Shungu, Dikoma C, Anjilvel, Satish, Chan, Stephen, Ellis, Steven P, Xanthopoulos, Eric, Malaspina, Dolores, Gorman, Jack M, Mann, J.John, Laruelle, Marc, Kaufmann, Charles A

“…The hippocampus is a site of previously reported structural and functional abnormalities in schizophrenia. We used magnetic resonance imaging (MRI) and proton…”
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Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the α7-nicotinic acetylcholine receptor subunit gene (CHRNA7) by Freedman, Robert, Leonard, Sherry, Gault, Judith M., Hopkins, Jan, Cloninger, C. Robert, Kaufmann, Charles A., Tsuang, Ming T., Farone, Stephen V., Malaspina, Dolores, Svrakic, Dragan M., Sanders, Alan, Gejman, Pablo

“…The transmission/disequilibrium test was used for fine mapping of the linkage of schizophrenia to the chromosome 15q13‐14 region, the site of a candidate gene,…”
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Suicidal Behavior in Schizophrenia: Characteristics of Individuals Who Had and Had Not Attempted Suicide by Harkavy-Friedman, Jill M., Restifo, Kathleen, Malaspina, Dolores, Kaufmann, Charles A., Amador, Xavier F., Yale, Scott A., Gorman, Jack M.

“…OBJECTIVE: This study compares demographic and clinical characteristics of 52 individuals with schizophrenia or schizoaffective disorder who had attempted…”
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Traumatic Brain Injury and Schizophrenia in Members of Schizophrenia and Bipolar Disorder Pedigrees by Malaspina, Dolores, Goetz, Raymond R., Friedman, Jill Harkavy, Kaufmann, Charles A., Faraone, Stephen V., Tsuang, Ming, Cloninger, C. Robert, Nurnberger, John I., Blehar, Mary C.

“…OBJECTIVE: Schizophrenia following a traumatic brain injury could be a phenocopy of genetic schizophrenia or the consequence of a gene-environment interaction…”
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Neurobiological Plausibility of Prenatal Nutritional Deprivation as a Risk Factor for Schizophrenia by BROWN, ALAN S, SUSSER, EZRA S, BUTLER, PAMELA D, ANDREWS, R RICHARDSON, KAUFMANN, CHARLES A, GORMAN, JACK M

“…Emerging evidence indicates that schizophrenia may in some cases be a neurodevelopmental disorder, resulting in part from the effects of prenatal exposures…”
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Minor physical anomalies in schizophrenia by Alexander, R C, Mukherjee, S, Richter, J, Kaufmann, C A

“…Using the Waldrop scale, minor physical anomalies were studied in 82 Caucasian subjects, including 41 schizophrenic and 8 bipolar adults, as well as 14 normal…”
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Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia by Lewis, Cathryn M., Levinson, Douglas F., Wise, Lesley H., DeLisi, Lynn E., Straub, Richard E., Hovatta, Iiris, Williams, Nigel M., Schwab, Sibylle G., Pulver, Ann E., Faraone, Stephen V., Brzustowicz, Linda M., Kaufmann, Charles A., Garver, David L., Gurling, Hugh M.D., Lindholm, Eva, Coon, Hilary, Moises, Hans W., Byerley, William, Shaw, Sarah H., Mesen, Andrea, Sherrington, Robin, O’Neill, F. Anthony, Walsh, Dermot, Kendler, Kenneth S., Ekelund, Jesper, Paunio, Tiina, Lönnqvist, Jouko, Peltonen, Leena, O’Donovan, Michael C., Owen, Michael J., Wildenauer, Dieter B., Maier, Wolfgang, Nestadt, Gerald, Blouin, Jean-Louis, Antonarakis, Stylianos E., Mowry, Bryan J., Silverman, Jeremy M., Crowe, Raymond R., Cloninger, C. Robert, Tsuang, Ming T., Malaspina, Dolores, Harkavy-Friedman, Jill M., Svrakic, Dragan M., Bassett, Anne S., Holcomb, Jennifer, Kalsi, Gursharan, McQuillin, Andrew, Brynjolfson, Jon, Sigmundsson, Thordur, Petursson, Hannes, Jazin, Elena, Zoëga, Tomas, Helgason, Tomas

“…Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to siblings of probands. Replication has been inconsistent for reports…”
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Physical Mapping, Linkage Analysis of a Putative Schizophrenia Locus on Chromosome 5q by Kaufmann, Charles A., DeLisi, Lynn E., Lehner, Thomas, Gilliam, T. Conrad

“…Two recent studies have suggested that a schizophrenia susceptibility locus may lie on the proximal long arm of chromosome 5. Partial trisomy of a 20-30…”
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NIMH genetics initiative millennium schizophrenia consortium: Linkage analysis of African-American pedigrees by Kaufmann, Charles A., Suarez, Brian, Malaspina, Dolores, Pepple, John, Svrakic, Dragan, Markel, Paul D., Meyer, Joanne, Zambuto, Christopher T., Schmitt, Karin, Matise, Tara Cox, Friedman, Jill M. Harkavy, Hampe, Carol, Lee, Hang, Shore, David, Wynne, Debra, Faraone, Stephen V., Tsuang, Ming T., Cloninger, C. Robert

“…The NIMH Genetics Initiative is a multi‐site collaborative study designed to create a national resource for genetic studies of complex neuropsychiatric…”
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Eye-blink rate in Tourette's syndrome by Karson, C N, Kaufmann, C A, Shapiro, A K, Shapiro, E

“…Gilles de la Tourette's syndrome is a hyperkinetic movement disorder in which an etiological role for dopaminergic hyperactivity has been proposed. Blink rate,…”
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Update on Research in Schizophrenia: Report on the Tarrytown Conference, April 13-15, 1986 by Pardes, Herbert, Kaufmann, Charles A., West, Anne

“…The Tarrytown Conference on Schizophrenia Research brought together representatives from a variety of disciplines to discuss the phenomenology, pathogenesis,…”
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Symptom dimensions in obsessive-compulsive disorder: Toward quantitative phenotypes by Leckman, James F., Zhang, Heping, Alsobrook, John P., Pauls, David L.

“…The authors review evidence of symptom dimensions in obsessive‐compulsive disorder (OCD) and their potential value as quantitative phenotypes in genetic…”
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Further investigation of a chromosome 15 locus in schizophrenia: Analysis of affected sibpairs from the NIMH genetics initiative by Leonard, Sherry, Gault, Judith, Moore, Theodore, Hopkins, Jan, Robinson, Misi, Olincy, Ann, Adler, Lawrence E., Cloninger, C. Robert, Kaufmann, Charles A., Tsuang, Ming T., Faraone, Stephen V., Malaspina, Dolores, Svrakic, Dragan M., Freedman, Robert

“…Linkage of a neurophysiological deficit associated with schizophrenia, i.e., the failure to inhibit the auditory P50 response, was previously reported at…”
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Histamine metabolites in cerebrospinal fluid of patients with chronic schizophrenia: their relationships to levels of other aminergic transmitters and ratings of symptoms by Prell, George D., Green, Jack Peter, Kaufmann, Charles A., Khandelwal, Jai K., Morrishow, Albert M., Kirch, Darrell G., Linnoila, Markku, Wyatt, Richard Jed

“…Levels of the histamine metabolites, tele-methylhistamine (t-MH) and tele-methylimidazoleacetic acid (t-MIAA), and metabolites of other aminergic transmitters…”
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Smaller right ear (left hemisphere) advantage for dichotic fused words in patients with schizophrenia by Bruder, G, Rabinowicz, E, Towey, J, Brown, A, Kaufmann, C A, Amador, X, Malaspina, D, Gorman, J M

“…The purposes of this study were to compare right ear (left hemisphere) advantage for dichotic words in schizophrenia and depression and to assess its…”
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Genome-wide search for schizophrenia susceptibility loci: The NIMH genetics initiative and millennium consortium by Cloninger, C. Robert, Kaufmann, Charles A., Faraone, Stephen V., Malaspina, Dolores, Svrakic, Dragan M., Harkavy-Friedman, Jill, Suarez, Brian K., Matise, Tara C., Shore, David, Lee, Hang, Hampe, Carol L., Wynne, Debra, Drain, Caroline, Markel, Paul D., Zambuto, Christopher T., Schmitt, Karin, Tsuang, Ming T.

“…Schizophrenia has a complex pattern of inheritance, indicative of interactions among multiple genes and environmental factors. The detection and replication of…”
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