Search Results - "Kaufman, RE"
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Gamma-Globin Gene Promoter Elements Required for Interaction With Globin Enhancers
Published in Blood (01-01-1998)“…Normal expression of the human β-globin domain genes is dependent on at least three types of regulatory elements located within the β-globin domain: the locus…”
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Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma
Published in Journal of clinical immunology (01-01-2005)“…CD7 is an immunoglobulin superfamily molecule expressed on T, NK, and pre-B lymphocytes. Previous studies have demonstrated a role for CD7 in T- and NK-cell…”
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Protecting subjects, preserving trust, promoting progress II: principles and recommendations for oversight of an institution's financial interests in human subjects research
Published in Academic medicine (01-02-2003)“…The AAMC Task Force on Financial Conflicts of Interest in Clinical Research issued this report, the second of two, in October 2002. (The first report is also…”
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Structure and function of the CD7 molecule
Published in Critical reviews in immunology (1999)“…CD7 is a single-domain Ig superfamily molecule expressed on human T and NK cells, as well as on cells in the early stages of T, B, and myeloid cell…”
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Cloning and structural analysis of the human c-kit gene
Published in Oncogene (01-07-1992)“…The recent identification of the mouse White spotting and Steel loci as genes encoding the c-kit receptor and its ligand, respectively, has shed light on the…”
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Hydroxyurea: specific therapy for sickle cell anemia? [editorial; comment]
Published in Blood (15-05-1992)Get full text
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Identification and Characterization of K12 (SECTM1), a Novel Human Gene That Encodes a Golgi-Associated Protein with Transmembrane and Secreted Isoforms
Published in Genomics (San Diego, Calif.) (01-02-1998)“…The investigation of a DNase-hypersensitive site upstream of the CD7 gene on chromosome 17q25 has led to the discovery of a novel human gene designated K12…”
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An Analysis of Alternatively Spliced CD45 mRNA Transcripts during T Cell Maturation in Humans
Published in Cellular immunology (01-05-1997)“…CD45 is a transmembrane protein tyrosine phosphatase found on nucleated hematopoietic cells. In humans, multiple protein isoforms of CD45 are produced by…”
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Regulation of nuclear and mitochondrial gene expression by contractile activity in skeletal muscle
Published in The Journal of biological chemistry (05-01-1986)“…Increased contractile activity of skeletal muscle augments the volume fraction and enzymatic capacity of mitochondria and suppresses the enzymatic capacity of…”
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Structure of the CD59-Encoding Gene: Further Evidence of a Relationship to Murine Lymphocyte Antigen Ly-6 Protein
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1992)“…The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of…”
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Comparison of human and Xenopus GATA-2 promoters
Published in Gene (14-11-1996)“…GATA proteins comprise a family of transcription factors that are required for appropriate development of hematopoietic lineages. In order to understand the…”
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Characterization of the DNase I hypersensitive site 3' of the human beta globin gene domain
Published in Blood (15-05-1993)“…The members of the human beta globin gene family are flanked by strong DNase I hypersensitive sites. The collection of sites 5' to the epsilon globin gene is…”
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Characterization of the DNase I Hypersensitive Site 3 of the Human β Globin Gene Domain
Published in Blood (15-05-1993)“…The members of the human β globin gene family are flanked by strong DNase I hypersensitive sites. The collection of sites 5′ to the ϵ globin gene is able to…”
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Hydroxyurea: Specific Therapy for Sickle Cell Anemia?
Published in Blood (15-05-1992)Get full text
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15
Isolation and Characterization of the Genomic Human CD7 Gene: Structural Similarity with the Murine Thy-1 Gene
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-1991)“…The human CD7 molecule is a 40-kDa member of the immunoglobulin gene superfamily that is expressed on T-lymphoid and myeloid precursors in fetal liver and bone…”
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Treatment of murine peritoneal macrophages with bacterial lipopolysaccharide alters expression of c-fos and c-myc oncogenes
Published in The Journal of immunology (1950) (15-10-1986)“…Expression of the c-fos, c-myc, and c-fms proto-oncogenes has been studied in thioglycollate-elicited murine peritoneal macrophages after exposure to…”
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Characterization of human CD7 transgenic mice
Published in The Journal of immunology (1950) (01-09-1995)“…CD7 is a 40-kDa transmembrane glycoprotein member of the lg gene superfamily expressed on most peripheral blood T lymphocytes and NK cells. CD7 is also…”
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A novel beta-globin mutation, beta Durham-NC [beta 114 Leu-->Pro], produces a dominant thalassemia-like phenotype
Published in Blood (15-02-1994)“…Mutations within exon 3 of the beta-globin gene are relatively uncommon, and many of these mutations produce a dominant thalassemia- like phenotype. We…”
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A novel β-globin mutation, βdurham-NC[β114 Leu → Pro], produces a dominant thalassemia-like phenotype
Published in Blood (15-02-1994)“…Mutations within exon 3 of the beta-globin gene are relatively uncommon, and many of these mutations produce a dominant thalassemia-like phenotype. We describe…”
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