Search Results - "Katz‐Brull, Rachel"

Parahydrogen‐Based Hyperpolarization for Biomedicine by Hövener, Jan‐Bernd, Pravdivtsev, Andrey N., Kidd, Bryce, Bowers, C. Russell, Glöggler, Stefan, Kovtunov, Kirill V., Plaumann, Markus, Katz‐Brull, Rachel, Buckenmaier, Kai, Jerschow, Alexej, Reineri, Francesca, Theis, Thomas, Shchepin, Roman V., Wagner, Shawn, Bhattacharya, Pratip, Zacharias, Niki M., Chekmenev, Eduard Y.

“…Magnetic resonance (MR) is one of the most versatile and useful physical effects used for human imaging, chemical analysis, and the elucidation of molecular…”
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Increasing the sensitivity of hyperpolarized [15N2]urea detection by serial transfer of polarization to spin‐coupled protons by Kreis, Felix, Wright, Alan J., Somai, Vencel, Katz‐Brull, Rachel, Brindle, Kevin M.

“…Purpose Hyperpolarized 15N‐labeled molecules have been proposed as imaging agents for investigating tissue perfusion and pH. However, the sensitivity of direct…”
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Directly Bound Deuterons Increase X-Nuclei Hyperpolarization using Dynamic Nuclear Polarization by Rooney, Catriona H E, Gamliel, Ayelet, Shaul, David, Tyler, Damian J, Grist, James T, Katz-Brull, Rachel

“…Deuterated C sites in sugars (D-glucose and 2-deoxy-D-glucose) showed 6.3-to-17.5-fold higher solid-state dynamic nuclear polarization (DNP) levels than their…”
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Accumulation of 3‐aminopropylphosphonate in the ex vivo brain observed by phosphorus‐31 nuclear magnetic resonance by Shaul, David, Grieb, Benjamin, Lev‐Cohain, Naama, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…3‐aminopropylphosphonate (3‐APP) is known for its use as an exogenous indicator of extracellular volume and pH in phosphorus‐31 nuclear magnetic resonance (31P…”
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Correlation between lactate dehydrogenase/pyruvate dehydrogenase activities ratio and tissue pH in the perfused mouse heart: A potential noninvasive indicator of cardiac pH provided by hyperpolarized magnetic resonance by Shaul, David, Azar, Assad, Sapir, Gal, Uppala, Sivaranjan, Nardi‐Schreiber, Atara, Gamliel, Ayelet, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…Cardiovascular diseases account for more than 30% of all deaths worldwide and many could be ameliorated with early diagnosis. Current cardiac imaging…”
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Hyperpolarized product selective saturating‐excitations for determination of changes in metabolic reaction rates in real‐time by Harris, Talia, Uppala, Sivaranjan, Lev‐Cohain, Naama, Adler‐Levy, Yael, Shaul, David, Nardi‐Schreiber, Atara, Sapir, Gal, Azar, Assad, Gamliel, Ayelet, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…Investigation of hyperpolarized substrate metabolism has been showing utility in real‐time determination of in‐cell and in vivo enzymatic activities…”
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Long‐lived 15N Hyperpolarization and Rapid Relaxation as a Potential Basis for Repeated First Pass Perfusion Imaging – Marked Effects of Deuteration and Temperature by Harris, Talia, Gamliel, Ayelet, Uppala, Sivaranjan, Nardi‐Schreiber, Atara, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…Deuteration of the exchangeable hydrogens of [15N2]urea was found to prolong the T1 of the 15N sites to more than 3 min at physiological temperatures. This…”
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The Effect of Gadolinium Doping in [13C6,2H7]Glucose Formulations on 13C Dynamic Nuclear Polarization at 3.35 T by Harris, Talia, Gamliel, Ayelet, Nardi‐Schreiber, Atara, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…The promise of hyperpolarized glucose as a non‐radioactive imaging agent capable of reporting on multiple metabolic routes has led to recent advances in its…”
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Real‐time ALT and LDH activities determined in viable precision‐cut mouse liver slices using hyperpolarized [1‐13C]pyruvate—Implications for studies on biopsied liver tissues by Lev‐Cohain, Naama, Sapir, Gal, Harris, Talia, Azar, Assad, Gamliel, Ayelet, Nardi‐Schreiber, Atara, Uppala, Sivaranjan, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…Precision‐cut liver slices (PCLS) are widely used in liver research as they provide a liver model with all liver cell types in their natural architecture. The…”
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Real‐time ALT and LDH activities determined in viable precision‐cut mouse liver slices using hyperpolarized [1‐13C]pyruvate—Implications for studies on biopsied liver tissues by Lev‐Cohain, Naama, Sapir, Gal, Harris, Talia, Azar, Assad, Gamliel, Ayelet, Nardi‐Schreiber, Atara, Uppala, Sivaranjan, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

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Deuteration of a molecular probe for DNP hyperpolarization--a new approach and validation for choline chloride by Allouche-Arnon, Hyla, Lerche, Mathilde H, Karlsson, Magnus, Lenkinski, Robert E, Katz-Brull, Rachel

“…The promising dynamic nuclear polarization (DNP) for hyperpolarized (13)C-MRI/MRS of real-time metabolism in vivo is challenged by the limited number of agents…”
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In vivo magnetic resonance imaging of glucose - initial experience by Allouche-Arnon, Hyla, Wade, Trevor, Waldner, Lanette Friesen, Miller, Valentina N, Gomori, J Moshe, Katz-Brull, Rachel, McKenzie, Charles A

“…A new noninvasive, nonradioactive approach for glucose imaging using spin hyperpolarization technology and stable isotope labeling is presented. A glucose…”
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Tolerance of Rodents to an Intravenous Bolus Injection of Sodium Nitrate in a High Concentration by Katz-Brull, Rachel

“…Nitrate, the inorganic anion NO , is found in many foods and is an endogenous mammalian metabolite, which is supplied mostly through the diet. Although much is…”
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Signal enhancement of hyperpolarized 15 N sites in solution-increase in solid-state polarization at 3.35 T and prolongation of relaxation in deuterated water mixtures by Gamliel, Ayelet, Shaul, David, Gomori, J Moshe, Katz-Brull, Rachel

“…Hyperpolarized N sites have been found to be promising for generating long-lived hyperpolarized states in solution, and present a promising approach for…”
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A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis by Allouche-Arnon, Hyla, Gamliel, Ayelet, Barzilay, Claudia M, Nalbandian, Ruppen, Gomori, J Moshe, Karlsson, Magnus, Lerche, Mathilde H, Katz-Brull, Rachel

“…Choline as a reporter molecule has been investigated by in vivo magnetic resonance for almost three decades. Accumulation of choline metabolites (mainly the…”
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Real-time influence of intracellular acidification and Na + /H + exchanger inhibition on in-cell pyruvate metabolism in the perfused mouse heart: A 31 P-NMR and hyperpolarized 13 C-NMR study by Shaul, David, Lev-Cohain, Naama, Sapir, Gal, Sosna, Jacob, Gomori, J Moshe, Joskowicz, Leo, Katz-Brull, Rachel

“…Disruption of acid-base balance is linked to various diseases and conditions. In the heart, intracellular acidification is associated with heart failure,…”
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Real‐time influence of intracellular acidification and Na+/H+ exchanger inhibition on in‐cell pyruvate metabolism in the perfused mouse heart: A 31P‐NMR and hyperpolarized 13C‐NMR study by Shaul, David, Naama Lev‐Cohain, Sapir, Gal, Sosna, Jacob, J Moshe Gomori, Joskowicz, Leo, Rachel Katz‐Brull

“…Disruption of acid–base balance is linked to various diseases and conditions. In the heart, intracellular acidification is associated with heart failure,…”
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Biochemical phosphates observed using hyperpolarized 31P in physiological aqueous solutions by Nardi-Schreiber, Atara, Gamliel, Ayelet, Harris, Talia, Sapir, Gal, Sosna, Jacob, Gomori, J. Moshe, Katz-Brull, Rachel

“…The dissolution-dynamic nuclear polarization technology had previously enabled nuclear magnetic resonance detection of various nuclei in a hyperpolarized…”
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The metabolic representation of ischemia in rat brain slices: A hyperpolarized 13 C magnetic resonance study by Shaul, David, Grieb, Benjamin, Sapir, Gal, Uppala, Sivaranjan, Sosna, Jacob, Gomori, J Moshe, Katz-Brull, Rachel

“…The ischemic penumbra in stroke is not clearly defined by today's available imaging tools. This study aimed to develop a model system and noninvasive…”
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The metabolic representation of ischemia in rat brain slices: A hyperpolarized 13C magnetic resonance study by Shaul, David, Grieb, Benjamin, Sapir, Gal, Uppala, Sivaranjan, Sosna, Jacob, Gomori, J. Moshe, Katz‐Brull, Rachel

“…The ischemic penumbra in stroke is not clearly defined by today's available imaging tools. This study aimed to develop a model system and noninvasive…”
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