Search Results - "Katz, Zachary B"

Quantifying Protein-mRNA Interactions in Single Live Cells by Wu, Bin, Buxbaum, Adina R., Katz, Zachary B., Yoon, Young J., Singer, Robert H.

“…Specific binding proteins are crucial for the correct spatiotemporal expression of mRNA. To understand this process, a method is required to characterize…”
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A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli by Katz, Zachary B, Novotná, Lucie, Blount, Amy, Lillemeier, Björn F

“…Lillemeier and colleagues describe a cycle of recruitment, activation and release of Zap70 kinase at phosphorylated T cell antigen receptors. According to this…”
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Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes by Katz, Zachary B, English, Brian P, Lionnet, Timothée, Yoon, Young J, Monnier, Nilah, Ovryn, Ben, Bathe, Mark, Singer, Robert H

“…Messenger RNA localization is important for cell motility by local protein translation. However, while single mRNAs can be imaged and their movements tracked…”
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i-shaped antibody engineering enables conformational tuning of biotherapeutic receptor agonists by Romei, Matthew G., Leonard, Brandon, Katz, Zachary B., Le, Daniel, Yang, Yanli, Day, Eric S., Koo, Christopher W., Sharma, Preeti, Bevers III, Jack, Kim, Ingrid, Dai, Huiguang, Farahi, Farzam, Lin, May, Shaw, Andrey S., Nakamura, Gerald, Sockolosky, Jonathan T., Lazar, Greg A.

“…The ability to leverage antibodies to agonize disease relevant biological pathways has tremendous potential for clinical investigation. Yet while antibodies…”
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mRNA on the Move: The Road to Its Biological Destiny by Eliscovich, Carolina, Buxbaum, Adina R., Katz, Zachary B., Singer, Robert H.

“…Cells have evolved to regulate the asymmetric distribution of specific mRNA targets to institute spatial and temporal control over gene expression. Over the…”
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Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling by Katz, Zachary B., Zhang, Chen, Quintana, Ariel, Lillemeier, Björn F., Hogan, Patrick G.

“…ORAI1 Ca 2+ channels in the plasma membrane (PM) are gated by STIM1 at endoplasmic reticulum (ER)-PM junctions to effect store-dependent Ca 2+ entry into…”
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Tagged actin mRNA dysregulation in IGF2BP1[Formula: see text] mice by Núñez, Leti, Buxbaum, Adina R, Katz, Zachary B, Lopez-Jones, Melissa, Nwokafor, Chiso, Czaplinski, Kevin, Pan, Feng, Rosenberg, Jason, Monday, Hannah R, Singer, Robert H

“…Gene expression is tightly regulated by RNA-binding proteins (RBPs) to facilitate cell survival, differentiation, and migration. Previous reports have shown…”
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International perspectives on the development, application, and evaluation of a multicancer early detection strategy by Johnson, Sonali E., Jayasekar Zurn, Shalini, Anderson, Benjamin O., Vetter, Beatrice N., Katz, Zachary B., Milner, Danny A.

“…The development and implementation of a multicancer early detection (MCED) test that is effective and affordable has the potential to change cancer care…”
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β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration by Katz, Zachary B, Wells, Amber L, Park, Hye Yoon, Wu, Bin, Shenoy, Shailesh M, Singer, Robert H

“…Directed cell motility is at the basis of biological phenomena such as development, wound healing, and metastasis. It has been shown that substrate attachments…”
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Tagged actin mRNA dysregulation in IGF2BP1Formula: see text mice by Núñez, Leti, Buxbaum, Adina R, Katz, Zachary B, Lopez-Jones, Melissa, Nwoka, Chiso, Czaplinski, Kevin, Pan, Feng, Rosenberg, Jason, Monday, Hannah R, Singer, Robert H

“…Gene expression is tightly regulated by RNA-binding proteins (RBPs) to facilitate cell survival, differentiation, and migration. Previous reports have shown…”
Get full text