Search Results - "Katz, S I"

Large protein as a potential target for use in rabies diagnostics by Santos Katz, I S, Dias, M H, Lima, I F, Chaves, L B, Ribeiro, O G, Scheffer, K C, Iwai, L K

“…Rabies is a zoonotic viral disease that remains a serious threat to public health worldwide. The rabies lyssavirus (RABV) genome encodes five structural…”
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Induction of skewed Th1/Th2 T-cell differentiation via subcutaneous immunization with Freund's adjuvant by Shibaki, A., Katz, S. I.

“…: CD4+ T cells differentiate into at least two distinct subsets, Th1 and Th2, that are characterized by their cytokine‐producing profiles. In this study, we…”
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Early Molecular Events in the Induction Phase of Contact Sensitivity by Enk, Alexander H., Katz, Stephen I.

“…To assess changes in epidermis-derived cytokine mRNA levels early in the afferent phase of allergic contact sensitivity, total epidermal mRNA was analyzed at…”
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Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance by Enk, AH, Angeloni, VL, Udey, MC, Katz, SI

“…IL-10 is a product of activated keratinocytes and is released during the induction phase of contact sensitivity. As IL-10 effects have been described as being…”
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Pioneers in Dermatology and Venereology: an interview with Stephen I. Katz, MD, PhD by Katz, S.I.

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An essential role for Langerhans cell-derived IL-1 beta in the initiation of primary immune responses in skin by Enk, AH, Angeloni, VL, Udey, MC, Katz, SI

“…Langerhans cells (LC) are Ag-presenting cells required for induction of primary immune responses in skin. After activation by Ag, LC express increased levels…”
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Identification and induction of keratinocyte-derived IL-10 by Enk, AH, Katz, SI

“…It has previously been demonstrated that the epidermis is a rich source of proinflammatory cytokines and growth factors and that complex interactions between…”
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Recognition of Desmoglein 3 by Autoreactive T Cells in Pemphigus Vulgaris Patients and Normals by Hertl, Michael, Amagai, Masayuki, Sundaram, Hema, Stanley, John, Ishii, Ken, Katz, Stephen I.

“…Pemphigus vulgaris (PV) is an autoimmune blistering disease of the skin and is caused by autoantibodies against desmoglein 3 (Dsg3) on epidermal keratinocytes…”
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Phenotypic and functional characteristics of in vivo-activated Langerhans cells by Aiba, S, Katz, SI

“…After short term culture (2 to 3 days), Langerhans cells (LC) exhibit increased class II MHC Ag and become more potent APC than freshly obtained LC in primary…”
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Characterization of the Th17 profile immune response in cases of human rabies transmitted by dogs and its interference in the disease pathogenesis by Santos, L.B., Guedes, F., Achkar, S.M., Duarte, M.I.S., Katz, I.S.S., Silva, S.R., Fernandes, E.R.

“…The Th17 profile immune response is influenced by the presence of cytokines such as IL-1, IL-6, TGF-β, IL-17, and IL-23. We sought to characterize the Th17…”
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Induction of IL-10 gene expression in human keratinocytes by UVB exposure in vivo and in vitro by Enk, CD, Sredni, D, Blauvelt, A, Katz, SI

“…Numerous studies have demonstrated that ultraviolet B (UVB) irradiation has profound effects on the skin and systemic immune systems. Because many of the…”
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Contact Hypersensitivity in MHC Class II-Deficient Mice Depends on CD8 T Lymphocytes Primed by Immunostimulating Langerhans Cells by Bouloc, Anne, Cavani, Andrea, Katz, Stephen I.

“…Studies to determine if CD4+ and/or CD8+ T cells are critical for the initiation and propagation of contact hypersensitivity (CHS) reactions have yielded…”
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Class II MHC-bearing keratinocytes induce antigen-specific unresponsiveness in hapten-specific Th1 clones by Gaspari, AA, Jenkins, MK, Katz, SI

“…Previous studies of Ia+ keratinocytes (KC) indicated that they functioned poorly or not at all when utilized as accessory cells for T cell activation. When Ia+…”
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Heterogeneous MHC II Restriction Pattern of Autoreactive Desmoglein 3 Specific T Cell Responses in Pemphigus Vulgaris Patients and Normals by Hertl, Michael, Karr, Robert W., Amagai, Masayuki, Katz, Stephen I.

“…Pemphigus vulgaris is a life threatening bullous autoimmune disease of the skin mediated by autoantibodies against desmoglein 3 (Dsg3) on epidermal…”
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Cytokine Gene Expression during the Elicitation Phase of Contact Sensitivity: Regulation By Endogenous IL-4 by Asada, Hideo, Linton, Jay, Katz, Stephon I.

“…Recent studies have focused on characterizing the cytokine profile produced in the epidermis during the sensitization phase of contact sensitivity (CS). Some…”
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Induction and functional characterization of class II MHC (Ia) antigens on murine keratinocytes by Gaspari, AA, Katz, SI

“…To induce Ia molecules on the surface of murine keratinocytes (KC), healthy mice were treated daily with i.p. injections of rIFN-gamma at a dose of 50,000…”
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The ability of cultured Langerhans cells to process and present protein antigens is MHC-dependent by Aiba, S, Katz, SI

“…There is controversy regarding the ability of short term (2 to 3 days) cultured epidermal Langerhans cells (cLC) to process and present intact protein Ag to…”
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Enhanced antigen-presenting capacity of cultured Langerhans' cells is associated with markedly increased expression of Ia antigen by Shimada, S, Caughman, SW, Sharrow, SO, Stephany, D, Katz, SI

“…Recent studies indicate that when epidermal Langerhans' cells (LC) are cultured for 2 to 3 days they, in comparison to freshly prepared LC, exhibit markedly…”
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Murine epidermal Langerhans cells and splenic dendritic cells present tumor-associated antigens to primed T cells by Cohen, P J, Cohen, P A, Rosenberg, S A, Katz, S I, Mulé, J J

“…We examined the ability of epidermal Langerhans cells and splenic dendritic cells to present tumor-associated antigens (Ag) to immune T cells…”
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Effects of ultraviolet radiation on human epidermal cell alloantigen presentation: initial depression of Langerhans cell-dependent function is followed by the appearance of T6- Dr+ cells that enhance epidermal alloantigen presentation by Cooper, KD, Fox, P, Neises, G, Katz, SI

“…The effects of ultraviolet radiation (UV) on the immune parameters of human epidermis were studied. We determined the effects of both in vitro and in vivo UV…”
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