Search Results - "Katsuyuki Hashimoto"

Identification and Characterization of a Novel Type of Membrane-Associated Prostaglandin E Synthase by Tanikawa, Naomi, Ohmiya, Yoshihiro, Ohkubo, Hiroaki, Hashimoto, Katsuyuki, Kangawa, Kenji, Kojima, Masami, Ito, Seiji, Watanabe, Kikuko

“…Membrane-associated prostaglandin E synthase (mPGE synthase) was previously purified to apparent homogeneity from the microsomal fraction of bovine heart…”
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Rate of evolution in brain-expressed genes in humans and other primates by Wang, Hurng-Yi, Chien, Huan-Chieh, Osada, Naoki, Hashimoto, Katsuyuki, Sugano, Sumio, Gojobori, Takashi, Chou, Chen-Kung, Tsai, Shih-Feng, Wu, Chung-I, Shen, C-K James

“…Brain-expressed genes are known to evolve slowly in mammals. Nevertheless, since brains of higher primates have evolved rapidly, one might expect acceleration…”
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Large-scale analysis of Macaca fascicularis transcripts and inference of genetic divergence between M. fascicularis and M. mulatta by Osada, Naoki, Hashimoto, Katsuyuki, Kameoka, Yosuke, Hirata, Makoto, Tanuma, Reiko, Uno, Yasuhiro, Inoue, Itsuro, Hida, Munetomo, Suzuki, Yutaka, Sugano, Sumio, Terao, Keiji, Kusuda, Jun, Takahashi, Ichiro

“…Cynomolgus macaques (Macaca fascicularis) are widely used as experimental animals in biomedical research and are closely related to other laboratory macaques,…”
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Expressed sequence tags from cynomolgus monkey ( Macaca fascicularis) liver: A systematic identification of drug-metabolizing enzymes by Uno, Yasuhiro, Suzuki, Yutaka, Wakaguri, Hiroyuki, Sakamoto, Yoshiko, Sano, Hitomi, Osada, Naoki, Hashimoto, Katsuyuki, Sugano, Sumio, Inoue, Ituro

“…The liver, a major organ for drug metabolism, is physiologically similar between monkeys and humans. However, the paucity of identified genes has hampered a…”
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Gene Expression Profiling Reveals the Mechanism and Pathophysiology of Mouse Liver Regeneration by Arai, Makoto, Yokosuka, Osamu, Chiba, Tetsuhiro, Imazeki, Fumio, Kato, Masaki, Hashida, Junya, Ueda, Youji, Sugano, Sumio, Hashimoto, Katsuyuki, Saisho, Hiromitsu, Takiguchi, Masaki, Seki, Naohiko

“…Comprehensive analysis of the changes in gene expression during liver regeneration was carried out by using an in-house microarray composed of 2,304 distinct…”
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Aberrant termination of reproduction-related TMEM30C transcripts in the hominoids by Osada, Naoki, Hashimoto, Katsuyuki, Hirai, Momoki, Kusuda, Jun

“…Finding genetic novelties that may contribute to human-specific physiology and diseases is a key issue of current biomedical studies. TMEM30C is a gene…”
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Regulation of constitutive expression of mouse PTEN by the 5′-untranslated region by BAOGUANG HAN, ZIZHENG DONG, YANG LIU, QUN CHEN, HASHIMOTO, Katsuyuki, ZHANG, Jian-Ting

“…PTEN tumor suppressor serves as a major negative regulator of survival signaling mediated by PI3 kinase/AKT/protein kinase B pathway, and is inactivated in…”
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Collection of Macaca fascicularis cDNAs derived from bone marrow, kidney, liver, pancreas, spleen, and thymus by Osada, Naoki, Hirata, Makoto, Tanuma, Reiko, Suzuki, Yutaka, Sugano, Sumio, Terao, Keiji, Kusuda, Jun, Kameoka, Yosuke, Hashimoto, Katsuyuki, Takahashi, Ichiro

“…Consolidating transcriptome data of non-human primates is essential to annotate primate genome sequences, and will facilitate research using non-human primates…”
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Mapping of chimpanzee full-length cDNAs onto the human genome unveils large potential divergence of the transcriptome by Sakate, Ryuichi, Suto, Yumiko, Imanishi, Tadashi, Tanoue, Tetsuya, Hida, Munetomo, Hayasaka, Ikuo, Kusuda, Jun, Gojobori, Takashi, Hashimoto, Katsuyuki, Hirai, Momoki

“…The genetic basis of the phenotypic difference between human and chimpanzee is one of the most actively pursued issues in current genomics. Although the…”
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Substitution Rate and Structural Divergence of 5′UTR Evolution: Comparative Analysis Between Human and Cynomolgus Monkey cDNAs by Osada, Naoki, Hirata, Makoto, Tanuma, Reiko, Kusuda, Jun, Hida, Munetomo, Suzuki, Yutaka, Sugano, Sumio, Gojobori, Takashi, Shen, C.-K. James, Wu, Chung-I, Hashimoto, Katsuyuki

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Isolation of Novel Mouse Genes Differentially Expressed in Brain Using cDNA Microarray by Yoshikawa, Tsutomu, Nagasugi, Yumi, Azuma, Takanori, Kato, Masaki, Sugano, Sumio, Hashimoto, Katsuyuki, Masuho, Yasuhiko, Muramatsu, Masa-aki, Seki, Naohiko

“…The major issue in the post-genome sequencing era is determination of gene expression patterns in variety of biological systems. A microarray system is a…”
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Analysis of 5'-end sequences of chimpanzee cDNAs by Sakate, Ryuichi, Osada, Naoki, Hida, Munetomo, Sugano, Sumio, Hayasaka, Ikuo, Shimohira, Naoko, Yanagi, Shinsuke, Suto, Yumiko, Hashimoto, Katsuyuki, Hirai, Momoki

“…We constructed full-length enriched cDNA libraries from chimpanzee brain, skin, and liver tissues by the oligo-capping method to establish a database of…”
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Identification of Sonic Hedgehog-Responsive Genes Using cDNA Microarray by Kato, Masaki, Seki, Naohiko, Sugano, Sumio, Hashimoto, Katsuyuki, Masuho, Yasuhiko, Muramatsu, Masa-aki, Kaibuchi, Kozo, Nakafuku, Masato

“…Sonic hedgehog (Shh) is a secreted signaling protein that plays important roles in a variety of developmental processes and also in pathogenesis of some human…”
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Pancreatic granular cell tumor combined with carcinoma in situ by Nojiri, Takuya, Unemura, Yasuki, Hashimoto, Katsuyuki, Yamazaki, Yoji, Ikegami, Masahiro

“…A 58‐year‐old man was treated for a granular cell tumor (GCT) of the pancreas; a very rarely occurring tumor. The patient, who had been followed for 6 years…”
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Search for Genes Positively Selected during Primate Evolution by 5′-End-Sequence Screening of Cynomolgus Monkey cDNAs by Osada, Naoki, Kusuda, Jun, Hirata, Makoto, Tanuma, Reiko, Hida, Munetomo, Sugano, Sumio, Hirai, Momoki, Hashimoto, Katsuyuki

“…It is possible to assess positive selection by using the ratio of Ka (nonsynonymous substitutions per plausible nonsynonymous sites) to Ks (synonymous…”
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Cynomolgus monkey testicular cDNAs for discovery of novel human genes in the human genome sequence by Osada, Naoki, Hida, Munetomo, Kusuda, Jun, Tanuma, Reiko, Hirata, Makoto, Suto, Yumiko, Hirai, Momoki, Terao, Keiji, Sugano, Sumio, Hashimoto, Katsuyuki

“…In order to contribute to the establishment of a complete map of transcribed regions of the human genome, we constructed a testicular cDNA library for the…”
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Molecular Cloning, Structural Characterization, and Chromosomal Mapping of the Human LECT2 Gene by Yamagoe, Satoshi, Kameoka, Yosuke, Hashimoto, Katsuyuki, Mizuno, Satoshi, Suzuki, Kazuo

“…We originally isolated LECT2 (leukocyte cell-derived chemotaxin 2) as a 16-kDa secreted protein having a human neutrophil chemotactic activity, then cloned…”
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Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis by Mesak, Felix M, Osada, Naoki, Hashimoto, Katsuyuki, Liu, Qing Y, Ng, Cheng E

“…As part of our investigation into the genetic basis of tumor cell radioresponse, we have isolated several clones with a wide range of responses to X-radiation…”
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Cloning and Chromosomal Mapping of Human Casein Kinase I γ2 (CSNK1G2) by Kitabayashi, Aya Nomura, Kusuda, Jun, Hirai, Momoki, Hashimoto, Katsuyuki

“…A clone of immature cDNA for human casein kinase I γ2 (CSNK1G2) was isolated by screening the human testis cDNA library with a PCR-amplified probe (about 400…”
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An Alu-linked Repetitive Sequence Corresponding to 280 Amino Acids Is Expressed in a Novel Bovine Protein, but Not in Its Human Homologue by Nobukuni, Takahiro, Kobayashi, Mariko, Omori, Akira, Ichinose, Sachiyo, Iwanaga, Toshihiko, Takahashi, Ichiro, Hashimoto, Katsuyuki, Hattori, Seisuke, Kaibuchi, Kozo, Miyata, Yoshihiko, Masui, Tohru, Iwashita, Shintaro

“…A novel protein harboring a 280-amino acid region from an Alu-linked repetitive sequence (bovine Alu-like dimer-driven family) was isolated from a bovine brain…”
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