Search Results - "Katsikis, Georgios"

Noninvasive monitoring of single-cell mechanics by acoustic scattering by Kang, Joon Ho, Miettinen, Teemu P., Chen, Lynna, Olcum, Selim, Katsikis, Georgios, Doyle, Patrick S., Manalis, Scott R.

“…The monitoring of mechanics in a single cell throughout the cell cycle has been hampered by the invasiveness of mechanical measurements. Here we quantify…”
Get full text

Hand-powered ultralow-cost paper centrifuge by Bhamla, M. Saad, Benson, Brandon, Chai, Chew, Katsikis, Georgios, Johri, Aanchal, Prakash, Manu

“…In a global-health context, commercial centrifuges are expensive, bulky and electricity-powered, and thus constitute a critical bottleneck in the development…”
Get full text

Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division by Kang, Joon Ho, Katsikis, Georgios, Li, Zhaoqi, Sapp, Kiera M., Stockslager, Max A., Lim, Daniel, Vander Heiden, Matthew G., Yaffe, Michael B., Manalis, Scott R., Miettinen, Teemu P.

“…The energetic demands of a cell are believed to increase during mitosis, but the rates of ATP synthesis and consumption during mitosis have not been…”
Get full text

Inertial and viscous flywheel sensing of nanoparticles by Katsikis, Georgios, Collis, Jesse F., Knudsen, Scott M., Agache, Vincent, Sader, John E., Manalis, Scott R.

“…Rotational dynamics often challenge physical intuition while enabling unique realizations, from the rotor of a gyroscope that maintains its orientation…”
Get full text

Analytical methods for process and product characterization of recombinant adeno-associated virus-based gene therapies by Gimpel, Andreas L., Katsikis, Georgios, Sha, Sha, Maloney, Andrew John, Hong, Moo Sun, Nguyen, Tam N.T., Wolfrum, Jacqueline, Springs, Stacy L., Sinskey, Anthony J., Manalis, Scott R., Barone, Paul W., Braatz, Richard D.

“…The optimization of upstream and downstream processes for production of recombinant adeno-associated virus (rAAV) with consistent quality depends on the…”
Get full text

Publisher Correction: Noninvasive monitoring of single-cell mechanics by acoustic scattering by Kang, Joon Ho, Miettinen, Teemu P., Chen, Lynna, Olcum, Selim, Katsikis, Georgios, Doyle, Patrick S., Manalis, Scott R.

“…The version of this paper originally published online contained an error in the x -axis of Fig. 2c: the LatB concentrations should be 0.4 and 1 μM, but during…”
Get full text

Resolving hidden subpopulations of filled AAVs by probing capsid integrity by Wu, Weida, Katsikis, Georgios

Get full text

Synchronous universal droplet logic and control by Katsikis, Georgios, Cybulski, James S., Prakash, Manu

“…Droplets are versatile digital materials; they can be produced at high throughput, perform chemical reactions as miniature beakers and carry biological…”
Get full text

Schistosoma mansoni cercariae swim efficiently by exploiting an elastohydrodynamic coupling by Krishnamurthy, Deepak, Katsikis, Georgios, Bhargava, Arjun, Prakash, Manu

“…The success with which the parasite Schistosoma mansoni infects humans is due largely to its efficient motility. Experiments, modelling and robotics suggest…”
Get full text

Cellular pathways of recombinant adeno-associated virus production for gene therapy by Sha, Sha, Maloney, Andrew J., Katsikis, Georgios, Nguyen, Tam N.T., Neufeld, Caleb, Wolfrum, Jacqueline, Barone, Paul W., Springs, Stacy L., Manalis, Scott R., Sinskey, Anthony J., Braatz, Richard D.

“…Recombinant adeno-associated viruses (rAAVs) are among the most important vectors for in vivo gene therapies. With the rapid development of gene therapy,…”
Get full text

Non-invasive monitoring of single-cell mechanics by acoustic scattering by Kang, Joon Ho, Miettinen, Teemu P., Chen, Lynna, Olcum, Selim, Katsikis, Georgios, Doyle, Patrick S., Manalis, Scott R.

“…Monitoring mechanics of the same cell throughout the cell cycle has been hampered by the invasiveness of mechanical measurements. Here, we quantify mechanical…”
Get full text

Weighing the DNA Content of Adeno-Associated Virus Vectors with Zeptogram Precision Using Nanomechanical Resonators by Katsikis, Georgios, Hwang, Iris E, Wang, Wade, Bhat, Vikas S, McIntosh, Nicole L, Karim, Omair A, Blus, Bartlomiej J, Sha, Sha, Agache, Vincent, Wolfrum, Jacqueline M, Springs, Stacy L, Sinskey, Anthony J, Barone, Paul W, Braatz, Richard D, Manalis, Scott R

“…Quantifying the composition of viral vectors used in vaccine development and gene therapy is critical for assessing their functionality. Adeno-associated virus…”
Get full text

Multidose transient transfection of human embryonic kidney 293 cells modulates recombinant adeno-associated virus2/5 Rep protein expression and influences the enrichment fraction of filled capsids by Srinivasan, Prasanna, Canova, Christopher T, Sha, Sha, Nguyen, Tam N T, Joseph, John, Sangerman, Jose, Maloney, Andrew J, Katsikis, Georgios, Ou, Rui Wen, Hong, Moo Sun, Ng, Jaclyn, Yuan, Arella, Antov, Daniel, Song, Sally, Chen, Wenyu, Neufeld, Caleb, Wolfrum, Jacqueline M, Barone, Paul W, Sinskey, Anthony J, Springs, Stacy L, Braatz, Richard D

“…Recombinant adeno-associated virus (rAAV) is a commonly used in vivo gene therapy vector because of its nonpathogenicity, long-term transgene expression, broad…”
Get full text

Suspended Nanochannel Resonator Arrays with Piezoresistive Sensors for High-Throughput Weighing of Nanoparticles in Solution by Gagino, Marco, Katsikis, Georgios, Olcum, Selim, Virot, Leopold, Cochet, Martine, Thuaire, Aurélie, Manalis, Scott R, Agache, Vincent

“…As the use of nanoparticles is expanding in many industrial sectors, pharmaceuticals, cosmetics among others, flow-through characterization techniques are…”
Get full text

High Quality Factor Suspended Nanochannel Resonator Devices, with Self-Oscillation Capacity by Aldrin, Katell, Furcatte, Thomas, Katsikis, Georgios, Jourdan, Guillaume, Olcum, Selim, Lepoetre, Aurelien, Beche, Jean-Francois, Boizot, Francois, Sansa, Marc, Navarro, Fabrice, Manalis, Scott, Agache, Vincent

“…While the self-sustaining oscillating behavior has already been studied on piezoresistive readout nanomechanical NEMS devices, it has never been demonstrated…”
Get full text

Inertial and viscous flywheel sensing of nanoparticles by Katsikis, Georgios, Collis, Jesse F, Knudsen, Scott M, Agache, Vincent, Sader, John E, Manalis, Scott R

“…Rotational dynamics often challenge physical intuition while enabling unique realizations, from the rotor of a gyroscope that maintains its orientation…”
Get full text

Generation of droplet arrays with rational number spacing patterns driven by a periodic energy landscape by Rinberg, Anatoly, Katsikis, Georgios, Prakash, Manu

“…Phys. Rev. E 96, 033108 (2017) The generation of droplets at low Reynolds numbers is driven by non-linear dynamics that give rise to complex patterns…”
Get full text

Synchronous Droplet Microfluidics: One "Clock" to rule them all by Katsikis, Georgios, Prakash, Manu

“…Controlling fluid droplets efficiently in the microscale is of great interest both from a basic science and a technology perspective. We have designed and…”
Get full text

Synchronous magnetic control of water droplets in bulk ferrofluid by Katsikis, Georgios, Breant, Alexandre, Rinberg, Anatoly, Prakash, Manu

“…We present a microfluidic platform for two-dimensional manipulation of water droplets immersed in bulk oil-based ferrofluid. Although non-magnetic, the…”
Get full text

Schistosoma mansoni cercariae exploit an elastohydrodynamic coupling to swim efficiently by Krishnamurthy, Deepak, Katsikis, Georgios, Bhargava, Arjun, Prakash, Manu

“…The motility of many parasites is critical for the infection process of their host, as exemplified by the transmission cycle of the blood fluke Schistosoma…”
Get full text