Search Results - "Katsanou, Efrosini S."

An adverse outcome pathway-based approach to assess steatotic mixture effects of hepatotoxic pesticides in vitro by Lichtenstein, Dajana, Luckert, Claudia, Alarcan, Jimmy, de Sousa, Georges, Gioutlakis, Michail, Katsanou, Efrosini S., Konstantinidou, Parthena, Machera, Kyriaki, Milani, Emanuela S., Peijnenburg, Ad, Rahmani, Roger, Rijkers, Deborah, Spyropoulou, Anastasia, Stamou, Marianna, Stoopen, Geert, Sturla, Shana J., Wollscheid, Bernd, Zucchini-Pascal, Nathalie, Braeuning, Albert, Lampen, Alfonso

“…Exposure to complex chemical mixtures requires a tiered strategy for efficient mixture risk assessment. As a part of the EuroMix project we developed an…”
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Identification of non-validated endocrine disrupting chemical characterization methods by screening of the literature using artificial intelligence and by database exploration by Zgheib, Elias, Kim, Min Ji, Jornod, Florence, Bernal, Kévin, Tomkiewicz, Céline, Bortoli, Sylvie, Coumoul, Xavier, Barouki, Robert, De Jesus, Kelly, Grignard, Elise, Hubert, Philippe, Katsanou, Efrosini S., Busquet, Francois, Audouze, Karine

“…•Regulatory tests for EDC identification do not assess all the endocrine pathways.•We provide a state-of-the-art analysis of existing non-validated test…”
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Modulation of CYP1A1 and CYP1A2 hepatic enzymes after oral administration of Chios mastic gum to male Wistar rats by Katsanou, Efrosini S, Kyriakopoulou, Katerina, Emmanouil, Christina, Fokialakis, Nikolas, Skaltsounis, Alexios-Leandros, Machera, Kyriaki

“…Chios mastic gum (CMG), a resin derived from Pistacia lentiscus var. chia, is known since ancient times for its pharmacological activities. CYP1A1 and CYP1A2…”
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Cytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: Modulation by adrenal and gonadal steroids by Katsanou, Efrosini S., Halabalaki, Maria, Aligiannis, Nektarios, Mitakou, Sofia, Skaltsounis, Alexios-Leandros, Alexi, Xanthippi, Pratsinis, Harris, Alexis, Michael N.

“…Although 2-arylbenzofuran phytoalexins are known for decades, their anticancer activity has not been studied systematically. We have previously reported on the…”
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Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro: A Case Study with Cyproconazole by Luckert, Claudia, Braeuning, Albert, de Sousa, Georges, Durinck, Sigrid, Katsanou, Efrosini S, Konstantinidou, Parthena, Machera, Kyriaki, Milani, Emanuela S, Peijnenburg, Ad A. C. M, Rahmani, Roger, Rajkovic, Andreja, Rijkers, Deborah, Spyropoulou, Anastasia, Stamou, Marianna, Stoopen, Geert, Sturla, Shana, Wollscheid, Bernd, Zucchini-Pascal, Nathalie, Lampen, Alfonso

“…Adverse outcome pathways (AOPs) describe causal relationships between molecular perturbation and adverse cellular effects and are being increasingly adopted…”
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Investigating the in vitro steatotic mixture effects of similarly and dissimilarly acting test compounds using an adverse outcome pathway-based approach by Alarcan, Jimmy, de Sousa, Georges, Katsanou, Efrosini S., Spyropoulou, Anastasia, Batakis, Petros, Machera, Kyriaki, Rahmani, Roger, Lampen, Alfonso, Braeuning, Albert, Lichtenstein, Dajana

“…Within the EuroMix project, we have previously developed an adverse outcome pathway (AOP)-based in vitro assay toolbox to investigate the combined effects of…”
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Maternal exposure to mixtures of dienestrol, linuron and flutamide. Part II: Endocrine-related gene expression assessment on male offspring rat testes by Katsanou, Efrosini S., Batakis, Petros, Spyropoulou, Anastasia, Schreiber, Elga, Bovee, Toine, Torrente, Margarita, Gómez, Maria Mercedes, Kumar, Vikas, Domingo, José Luis, Machera, Kyriaki

“…Exposure to endocrine-disrupting compounds (EDCs) during pregnancy and early development can lead to adverse developmental outcomes in offspring. One of the…”
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Maternal exposure to mixtures of dienestrol, linuron and flutamide. Part I: Feminization effects on male rat offspring by Schreiber, Elga, Garcia, Tània, González, Neus, Esplugas, Roser, Sharma, Raju Prasad, Torrente, Margarita, Kumar, Vikas, Bovee, Toine, Katsanou, Efrosini S., Machera, Kyriaki, Domingo, José Luis, Gómez, Mercedes

“…Exposure to endocrine-disrupting compounds (EDCs) during pregnancy can result in negative health effects in later generations, including sex changes and…”
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Comparative UHPLC-HRMS Profiling, Toxicological Assessment, and Protection Against H 2 O 2 -Induced Genotoxicity of Different Parts of Opuntia ficus indica by Tsafantakis, Nikolaos, Katsanou, Efrosini S, Kyriakopoulou, Katerina, Psarou, Eirini-Christina, Raptaki, Iliana, Skaltsounis, Alexios L, Audebert, Marc, Machera, Kyriaki A, Fokialakis, Nikolas

“…has been an important dietary source and a traditionally used medicinal plant. Given the promising health-promoting properties of this plant, a comparative…”
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Novel Dehydroepiandrosterone Derivatives with Antiapoptotic, Neuroprotective Activity by Calogeropoulou, Theodora, Avlonitis, Nicolaos, Minas, Vassilios, Alexi, Xanthippi, Pantzou, Athanasia, Charalampopoulos, Ioannis, Zervou, Maria, Vergou, Varvara, Katsanou, Efrosini S, Lazaridis, Iakovos, Alexis, Michael N, Gravanis, Achille

“…DHEA analogues with modifications at positions C3 or C17 were synthesized and evaluated for neuroprotective activity against the neural-crest-derived PC12 cell…”
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Chroman/Catechol Hybrids:  Synthesis and Evaluation of Their Activity against Oxidative Stress Induced Cellular Damage by Koufaki, Maria, Theodorou, Elissavet, Galaris, Dimitrios, Nousis, Lambros, Katsanou, Efrosini S, Alexis, Michael N

“…Three series of chromans substituted at positions 2 or 5 by catechol derivatives were synthesized, and their activity against oxidative stress induced cellular…”
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New hydroxystilbenoid derivatives endowed with neuroprotective activity and devoid of interference with estrogen and aryl hydrocarbon receptor-mediated transcription by Villalonga-Barber, Carolina, Meligova, Aggeliki K., Alexi, Xanthippi, Steele, Barry R., Kouzinos, Constantinos E., Screttas, Constantinos G., Katsanou, Efrosini S., Micha-Screttas, Maria, Alexis, Michael N.

“…A series of hydroxystilbenoid derivatives were synthesized and screened positive for neuroprotective activity and lack of interference with estrogen and aryl…”
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The estrogen receptor and polyphenols: molecular simulation studies of their interactions, a review by Lambrinidis, George, Halabalaki, Maria, Katsanou, Efrosini S., Skaltsounis, Alexios-Leandros, Alexis, Michael N., Mikros, Emmanuel

“…Estrogens exert their physiological effects by binding to the estrogen receptor (ER), a ligand-activated transcription factor, of the nuclear receptors'…”
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A novel quantitative flow cytometric method for measuring glucocorticoid receptor (GR) in cell lines: Correlation with the biochemical determination of GR by Voutsas, Ioannis F., Gritzapis, Angelos D., Alexis, Michael N., Katsanou, Efrosini S., Perez, Sonia, Baxevanis, Constantin N., Papamichail, Michael

“…Currently, a time consuming biochemical method is used for GR quantification. Here we compare the biochemical approach with a newly developed flow cytometric…”
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Maintenance of glucocorticoid receptor function following severe heat-shock of heat-conditioned cells by Mitsiou, Dimitra J., Siriani, Despina, Katsanou, Efrosini S., Florentin, Ida, Georgakopoulos, Anastasios, Alexis, Michael N.

“…The competence of the glucocorticoid receptor to regulate gene expression is thought to depend on Hsp70-driven continuous reactivation following spontaneous…”
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Urocortin, but Not Corticotropin-Releasing Hormone (CRH), Activates the Mitogen-Activated Protein Kinase Signal Transduction Pathway in Human Pregnant Myometrium: An Effect Mediated via R1α and R2β CRH Receptor Subtypes and Stimulation of Gq-Proteins by Grammatopoulos, Dimitris K, Randeva, Harpal S, Levine, Michael A, Katsanou, Efrosini S, Hillhouse, Edward W

“…CRH and CRH-related peptides such as urocortin mediate their actions in the human myometrium via activation of two distinct classes of CRH receptors, R1 and…”
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