Search Results - "Katryniok, Careen"

Trichostatin A induces 5‐lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3 by Pufahl, Laura, Katryniok, Careen, Schnur, Nicole, Sorg, Bernd L., Metzner, Julia, Grez, Manuel, Steinhilber, Dieter

“…The 5‐lipoxygenase (5‐LO) is the key enzyme in the formation of leukotrienes. We have previously shown that the histone deacetylase (HDAC) inhibitor…”
Get full text

The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes by Schnur, Nicole, Seuter, Sabine, Katryniok, Careen, Rådmark, Olof, Steinhilber, Dieter

“…The histone deacetylase inhibitor trichostatin A (TsA) potently induces 5-lipoxygenase (5-LO) promoter activity in reporter gene assays as well as 5-LO mRNA…”
Get full text

Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity by Katryniok, Careen, Schnur, Nicole, Gillis, Ad, von Knethen, Andreas, Sorg, Bernd L., Looijenga, Leendert, Rådmark, Olof, Steinhilber, Dieter

“…Human 5-lipoxygenase (5-LO) is the key enzyme in the formation of inflammatory leukotrienes. 5-LO gene expression is mainly restricted to B cells and cells of…”
Get full text