Search Results - "Katre, A."

Stem Cell Pathways Contribute to Clinical Chemoresistance in Ovarian Cancer by STEG, Adam D, BEVIS, Kerri S, KATRE, Ashwini A, ZIEBARTH, Angela, DOBBIN, Zachary C, ALVAREZ, Ronald D, KUI ZHANG, CONNER, Michael, LANDEN, Charles N

“…Within heterogeneous tumors, subpopulations often labeled cancer stem cells (CSC) have been identified that have enhanced tumorigenicity and chemoresistance in…”
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Manipulating the Wnt/β-catenin signaling pathway to promote anti-tumor immune infiltration into the TME to sensitize ovarian cancer to ICB therapy by Wall, J.A., Meza-Perez, S., Scalise, C.B., Katre, A., Londoño, A.I., Turbitt, W.J., Randall, T., Norian, L.A., Arend, R.C.

“…Immune checkpoint blockade (ICB) therapy shows limited efficacy in ovarian cancers due to the “cold” immune phenotype surrounding these tumors. Previous…”
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Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer by Landen, Jr, Charles N, Goodman, Blake, Katre, Ashwini A, Steg, Adam D, Nick, Alpa M, Stone, Rebecca L, Miller, Lance D, Mejia, Pablo Vivas, Jennings, Nicolas B, Gershenson, David M, Bast, Jr, Robert C, Coleman, Robert L, Lopez-Berestein, Gabriel, Sood, Anil K

“…Aldehyde dehydrogenase-1A1 (ALDH1A1) expression characterizes a subpopulation of cells with tumor-initiating or cancer stem cell properties in several…”
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Understanding the effect of mechanical forces on ovarian cancer progression by Martinez, A., Buckley, M., Scalise, C.B., Katre, A.A., Dholakia, J.J., Crossman, D., Birrer, M.J., Berry, J.L., Arend, R.C.

“…Mechanical forces including tension, compression, and shear stress are increasingly implicated in tumor progression and metastasis. Understanding the…”
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Targeting RNA-Polymerase I in Both Chemosensitive and Chemoresistant Populations in Epithelial Ovarian Cancer by Cornelison, Robert, Dobbin, Zachary C, Katre, Ashwini A, Jeong, Dae Hoon, Zhang, Yinfeng, Chen, Dongquan, Petrova, Yuliya, Llaneza, Danielle C, Steg, Adam D, Parsons, Laura, Schneider, David A, Landen, Charles N

“…A hallmark of neoplasia is increased ribosome biogenesis, and targeting this process with RNA polymerase I (Pol I) inhibitors has shown some efficacy. We…”
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The antitumor effects of entinostat in ovarian cancer require adaptive immunity by Smith, Haller J., McCaw, Tyler R., Londono, Angelina I., Katre, Ashwini A., Meza‐Perez, Selene, Yang, Eddy S., Forero, Andres, Buchsbaum, Donald J., Randall, Troy D., Straughn, Jr, J. Michael, Norian, Lyse A., Arend, Rebecca C.

“…Background Ovarian cancer is poorly immunogenic; however, increased major histocompatibility complex class II (MHCII) expression correlates with improved…”
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Molecular Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma by Arend, Rebecca C, Londoño, Angelina I, Montgomery, Allison M, Smith, Haller J, Dobbin, Zachary C, Katre, Ashwini A, Martinez, Alba, Yang, Eddy S, Alvarez, Ronald D, Huh, Warner K, Bevis, Kerri S, Straughn, Jr, J Michael, Estes, Jacob M, Novak, Lea, Crossman, David K, Cooper, Sara J, Landen, Charles N, Leath, 3rd, Charles A

“…While high-grade serous ovarian carcinoma (HGSOC) is the most common histologic subtype of ovarian cancer, significant tumor heterogeneity exists. In addition,…”
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Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease by Liu, R.-M, van Groen, T, Katre, A, Cao, D, Kadisha, I, Ballinger, C, Wang, L, Carroll, S.L, Li, L

“…Abstract Accumulation of amyloid beta peptide (Aβ) in the brain is a pathological hallmark of Alzheimer's disease (AD); the underlying mechanism, however, is…”
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Targeting the Notch Ligand Jagged1 in Both Tumor Cells and Stroma in Ovarian Cancer by STEG, Adam D, KATRE, Ashwini A, LANDEN, Charles N, GOODMAN, Blake, HAN, Hee-Dong, NICK, Alpa M, STONE, Rebecca L, COLEMAN, Robert L, ALVAREZ, Ronald D, LOPEZ-BERESTEIN, Gabriel, SOOD, Anil K

“…Jagged1, a Notch ligand, is expressed on both tumor epithelial and endothelial cells and therefore may be amenable to dual targeting of the tumor stroma and…”
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Sensitivity of LHC experiments to exotic highly ionising particles by De Roeck, A., Katre, A., Mermod, P., Milstead, D., Sloan, T.

“…The experiments at the Large Hadron Collider (LHC) are able to discover or set limits on the production of exotic particles with TeV-scale masses possessing…”
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Higher glucose, insulin and insulin resistance (HOMA-IR) in childhood predict adverse cardiovascular risk in early adulthood: the Pune Children’s Study by Yajnik, Chittaranjan S., Katre, Prachi A., Joshi, Suyog M., Kumaran, Kalyanaraman, Bhat, Dattatray S., Lubree, Himangi G., Memane, Nilam, Kinare, Arun S., Pandit, Anand N., Bhave, Sheila A., Bavdekar, Ashish, Fall, Caroline H. D.

“…Aims/hypothesis The Pune Children’s Study aimed to test whether glucose and insulin measurements in childhood predict cardiovascular risk factors in young…”
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Spuriously High Prevalence of Prediabetes Diagnosed by HbA1c in Young Indians Partly Explained by Hematological Factors and Iron Deficiency Anemia by Hardikar, Pallavi S, Joshi, Suyog M, Bhat, Dattatray S, Raut, Deepa A, Katre, Prachi A, Lubree, Himangi G, Jere, Abhay, Pandit, Anand N, Fall, Caroline H.D, Yajnik, Chittaranjan S

“…OBJECTIVE: To examine the influence of glycemic and nonglycemic parameters on HbA1c concentrations in young adults, the majority of whom had normal glucose…”
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Tracking of cardiovascular risk factors from childhood to young adulthood — the Pune Children's Study by Joshi, Suyog M, Katre, Prachi A, Kumaran, Kalyanaraman, Joglekar, Charudatta, Osmond, Clive, Bhat, Dattatray S, Lubree, Himangi, Pandit, Anand, Yajnik, Chittaranjan S, Fall, Caroline H.D

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Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer by ZIEBARTH, Angela J, NOWSHEEN, Somaira, YANG, Eddy S, LANDEN, Charles N, STEG, Adam D, SHAH, Monjri M, KATRE, Ashwini A, DOBBIN, Zachary C, HAN, Hee-Dong, LOPEZ-BERESTEIN, Gabriel, SOOD, Anil K, CONNER, Michael

“…Endoglin (CD105) is a membranous protein overexpressed in tumor-associated endothelial cells, chemoresistant populations of ovarian cancer cells, and…”
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Class I histone deacetylase inhibition promotes CD8 T cell activation in ovarian cancer by McCaw, Tyler R., Goel, Nidhi, Brooke, Dewey J., Katre, Ashwini A., Londoño, Angelina I., Smith, Haller J., Randall, Troy D., Arend, Rebecca C.

“…Objective Patients with epithelial ovarian cancer (EOC) typically present with late‐stage disease, posing a significant challenge to treatment. Although taxane…”
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Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer by Doo, David W., Meza-Perez, Selene, Londoño, Angelina I., Goldsberry, Whitney N., Katre, Ashwini A., Boone, Jonathan D., Moore, Dylana J., Hudson, Cindy T., Betella, Ilaria, McCaw, Tyler R., Gangrade, Abhishek, Bao, Riyue, Luke, Jason J., Yang, Eddy S., Birrer, Michael J., Starenki, Dmytro, Cooper, Sara J., Buchsbaum, Donald J., Norian, Lyse A., Randall, Troy D., Arend, Rebecca C.

“…Background: The Wnt/β-catenin pathway is linked to tumorigenesis in a variety of tumors and promotes T cell exclusion and resistance to checkpoint inhibitors…”
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Utilization of a 3-D tissue engineered model to investigate the effects of perfusion on gynecologic cancer biology by Martinez, Alba, Buckley, Molly S, Scalise, Carly B, Wang, Dezhi, Katre, Ashwini A, Birrer, Michael J, Berry, Joel L, Arend, Rebecca C

“…Among gynecologic malignancies, ovarian cancer (OC) has the poorest survival rate, and its clinical management remains challenging due to the high rate of…”
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Development of a magnetometer-based search strategy for stopped monopoles at the Large Hadron Collider by De Roeck, A., Hächler, H.-P., Hirt, A. M., Joergensen, M.-D., Katre, A., Mermod, P., Milstead, D., Sloan, T.

“…If produced in high energy particle collisions at the LHC, magnetic monopoles could stop in material surrounding the interaction points. Obsolete parts of the…”
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Using heterogeneity of the patient-derived xenograft model to identify the chemoresistant population in ovarian cancer by Dobbin, Zachary C., Katre, Ashwini A., Steg, Adam D., Erickson, Britt K., Shah, Monjri M., Alvarez, Ronald D., Conner, Michael G., Schneider, David, Chen, Dongquan, Landen, Charles N.

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Towards personalized PARP therapy: XRT-induced Rad51 predicts re- sponse to ABT-888 in ovarian cancer by Shah, M, Nowsheen, S, Katre, A, Dobbin, Z, Erickson, B, Alvarez, R, Konstantinopoulos, P, Yang, E, Landen, C

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