Search Results - "Katonova, Alzbeta"
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Plasminogen activator inhibitor‐1 serum levels in frontotemporal lobar degeneration
Published in Journal of cellular and molecular medicine (01-03-2024)“…Plasminogen activator inhibitor‐1 (PAI‐1) impedes brain plasmin synthesis. Reduced plasmin activity facilitates cumulation of amyloid beta (Aβ) in Alzheimer's…”
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Effect of a Vegan Diet on Alzheimer's Disease
Published in International journal of molecular sciences (29-11-2022)“…There is evidence indicating that a vegan diet could be beneficial in the prevention of neurodegenerative disorders, including Alzheimer's disease (AD). The…”
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Alzheimer’s Disease Severity Is Associated with an Imbalance in Serum Levels of Enzymes Regulating Plasmin Synthesis
Published in Pharmaceuticals (Basel, Switzerland) (29-08-2022)“…Alzheimer’s disease (AD) is a central nervous system (CNS) disease characterized by loss of memory, cognitive functions, and neurodegeneration. Plasmin is an…”
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CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional analysis
Published in Alzheimer's research & therapy (06-09-2024)“…There is initial evidence suggesting that biomarker neurogranin (Ng) may distinguish Alzheimer's disease (AD) from other neurodegenerative diseases. Therefore,…”
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Differentiation of clinically diagnosed patients with aMCI and dementia from cognitively unimpaired older adults using plasma and serum p‐tau 181 and NfL
Published in Alzheimer's & dementia (01-12-2023)“…Background Blood‐based biomarkers give the possibility of having a less invasive, more acceptable to patients, and cost‐ and time‐efficient screening tool…”
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The molar ratio between PAI‐1 and BDNF is increased in Alzheimer’s disease patients with full dementia and negatively correlates with MMSE score
Published in Alzheimer's & dementia (01-12-2023)“…Background In a previous study, we demonstrated that the enzyme plasminogen activator inhibitor‐1 (PAI‐1), which inhibits plasmin synthesis in the central…”
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Levels of Mitophagy Biomarkers Differ Between Individuals With Alzheimer’s disease and Frontotemporal Lobar Degeneration
Published in Alzheimer's & dementia (01-12-2023)“…Background Reduced removal of dysfunctional mitochondria has been implicated in the pathogenesis of many neurodegenerative diseases, including Alzheimer’s…”
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Mitophagy biomarkers are changed in the continuum of Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2023)“…Background Autophagy is a cellular self “garbage clearance ”system through which cells eliminate and recycle dysfunctional cytoplasmatic components, such as…”
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Serum PAI-1/BDNF Ratio Is Increased in Alzheimer’s Disease and Correlates with Disease Severity
Published in ACS omega (03-10-2023)“…We previously demonstrated that serum levels of plasminogen activator inhibitor-1 (PAI-1), which inhibits both the tissue plasminogen activator (tPA) and…”
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Alterations of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer disease
Published in Autophagy (02-08-2024)“…Defective mitophagy is consistently found in postmortem brain and iPSC-derived neurons from Alzheimer disease (AD) patients. However, there is a lack of…”
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