Search Results - "Katoh, Hiroto"

Lifestyles, genetics, and future perspectives on gastric cancer in east Asian populations by Katoh, Hiroto, Ishikawa, Shumpei

“…The prevalence of gastric cancer (GC) differs among regions worldwide, with the highest occurrence in east Asia. Thus, its etiology, with respect to ethnic…”
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Immune repertoire profiling for disease pathobiology by Katoh, Hiroto, Komura, Daisuke, Furuya, Genta, Ishikawa, Shumpei

“…Lymphocytes consist of highly heterogeneous populations, each expressing a specific cell surface receptor corresponding to a particular antigen. Lymphocytes…”
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Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma by Kakiuchi, Miwako, Nishizawa, Takashi, Ueda, Hiroki, Gotoh, Kengo, Tanaka, Atsushi, Hayashi, Akimasa, Yamamoto, Shogo, Tatsuno, Kenji, Katoh, Hiroto, Watanabe, Yoshiaki, Ichimura, Takashi, Ushiku, Tetsuo, Funahashi, Shinichi, Tateishi, Keisuke, Wada, Ikuo, Shimizu, Nobuyuki, Nomura, Sachiyo, Koike, Kazuhiko, Seto, Yasuyuki, Fukayama, Masashi, Aburatani, Hiroyuki, Ishikawa, Shumpei

“…Shumpei Ishikawa and colleagues report the identification of recurrent gain-of-function mutations in RHOA in diffuse-type gastric carcinomas. Diffuse-type…”
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Hunner-Type (Classic) Interstitial Cystitis: A Distinct Inflammatory Disorder Characterized by Pancystitis, with Frequent Expansion of Clonal B-Cells and Epithelial Denudation by Maeda, Daichi, Akiyama, Yoshiyuki, Morikawa, Teppei, Kunita, Akiko, Ota, Yasunori, Katoh, Hiroto, Niimi, Aya, Nomiya, Akira, Ishikawa, Shumpei, Goto, Akiteru, Igawa, Yasuhiko, Fukayama, Masashi, Homma, Yukio

“…Interstitial cystitis (IC) is a chronic bladder disease with urinary frequency, bladder discomfort or bladder pain of unknown etiology. Based on cystoscopic…”
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Genomic pathobiology of gastric carcinoma by Katoh, Hiroto, Ishikawa, Shumpei

“…With the recent advances in genome sequencing technologies, comprehensive cancer genomic profiling has revealed the in‐depth molecular mechanisms of gastric…”
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Non-Helicobacter pylori Helicobacter (NHPH) positive gastric cancer by Yasuda, Tomohiko, Lee, Hyun Seok, Nam, Su Youn, Katoh, Hiroto, Ishibashi, Yuko, Yamagata Murayama, Somay, Matsui, Hidenori, Masuda, Hiroki, Rimbara, Emiko, Sakurazawa, Nobuyuki, Suzuki, Hideyuki, Yoshida, Hiroshi, Seto, Yasuyuki, Ishikawa, Shumpei, Jeon, Seong Woo, Nakamura, Masahiko, Nomura, Sachiyo

“…Genetic analysis and culturing techniques for gastric non- Helicobacter pylori Helicobacter (NHPH) are progressing. NHPH is reported to accompany nodular…”
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Molecular Taxonomy of Interstitial Cystitis/Bladder Pain Syndrome Based on Whole Transcriptome Profiling by Next-Generation RNA Sequencing of Bladder Mucosal Biopsies by Akiyama, Yoshiyuki, Maeda, Daichi, Katoh, Hiroto, Morikawa, Teppei, Niimi, Aya, Nomiya, Akira, Sato, Yusuke, Kawai, Taketo, Goto, Akiteru, Fujimura, Tetsuya, Fukuhara, Hiroshi, Nakagawa, Tohru, Igawa, Yasuhiko, Ishikawa, Shumpei, Fukayama, Masashi, Kume, Haruki, Homma, Yukio

“…We systematically characterized gene expression, inflammation and neovascularization in patients with interstitial cystitis/bladder pain syndrome to obtain…”
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Stomach encyclopedia: Combined single-cell and spatial transcriptomics reveal cell diversity and homeostatic regulation of human stomach by Tsubosaka, Ayumu, Komura, Daisuke, Kakiuchi, Miwako, Katoh, Hiroto, Onoyama, Takumi, Yamamoto, Asami, Abe, Hiroyuki, Seto, Yasuyuki, Ushiku, Tetsuo, Ishikawa, Shumpei

“…The stomach is an important digestive organ with various biological functions. However, because of the complexity of its cellular and glandular composition,…”
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FOXP3: Genetic and epigenetic implications for autoimmunity by Katoh, Hiroto, Zheng, Pan, Liu, Yang

“…Abstract FOXP3 plays an essential role in the maintenance of self-tolerance and, thus, in preventing autoimmune diseases. Inactivating mutations of FOXP3 cause…”
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Pathological complete remission of relapsed tumor by photo‐activating antibody–mimetic drug conjugate treatment by Kaneko, Yudai, Yamatsugu, Kenzo, Yamashita, Takefumi, Takahashi, Kazuki, Tanaka, Toshiya, Aki, Sho, Tatsumi, Toshifumi, Kawamura, Takeshi, Miura, Mai, Ishii, Masazumi, Ohkubo, Kei, Osawa, Tsuyoshi, Kodama, Tatsuhiko, Ishikawa, Shumpei, Tsukagoshi, Masanobu, Chansler, Michael, Sugiyama, Akira, Kanai, Motomu, Katoh, Hiroto

“…Antibody–mimetic drug conjugate is a novel noncovalent conjugate consisting of an antibody‐mimetic recognizing a target molecule on the cancer cell surface and…”
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RHOA mutation in diffuse-type gastric cancer: a comparative clinicopathology analysis of 87 cases by Ushiku, Tetsuo, Ishikawa, Shumpei, Kakiuchi, Miwako, Tanaka, Atsushi, Katoh, Hiroto, Aburatani, Hiroyuki, Lauwers, Gregory Y., Fukayama, Masashi

“…Background Recent studies have discovered recurrent RHOA mutations in diffuse-type gastric cancers. These reports show mutant RhoA is an important cancer…”
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Multiancestry genomic and transcriptomic analysis of gastric cancer by Totoki, Yasushi, Saito-Adachi, Mihoko, Shiraishi, Yuichi, Komura, Daisuke, Nakamura, Hiromi, Suzuki, Akihiro, Tatsuno, Kenji, Rokutan, Hirofumi, Hama, Natsuko, Yamamoto, Shogo, Ono, Hanako, Arai, Yasuhito, Hosoda, Fumie, Katoh, Hiroto, Chiba, Kenichi, Iida, Naoko, Nagae, Genta, Ueda, Hiroki, Shihang, Chen, Sekine, Shigeki, Abe, Hiroyuki, Nomura, Sachiyo, Matsuura, Tetsuya, Sakai, Eiji, Ohshima, Takashi, Rino, Yasushi, Yeoh, Khay Guan, So, Jimmy, Sanghvi, Kaushal, Soong, Richie, Fukagawa, Akihiko, Yachida, Shinichi, Kato, Mamoru, Seto, Yasuyuki, Ushiku, Tetsuo, Nakajima, Atsushi, Katai, Hitoshi, Tan, Patrick, Ishikawa, Shumpei, Aburatani, Hiroyuki, Shibata, Tatsuhiro

“…Gastric cancer is among the most common malignancies worldwide, characterized by geographical, epidemiological and histological heterogeneity. Here, we report…”
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Epithelial Homeostasis: Elimination by Live Cell Extrusion by Katoh, Hiroto, Fujita, Yasuyuki

“…To maintain a functional and harmonious epithelial society, the number and quality of cells need to be tightly controlled. Two recent studies reveal a novel…”
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Universal encoding of pan-cancer histology by deep texture representations by Komura, Daisuke, Kawabe, Akihiro, Fukuta, Keisuke, Sano, Kyohei, Umezaki, Toshikazu, Koda, Hirotomo, Suzuki, Ryohei, Tominaga, Ken, Ochi, Mieko, Konishi, Hiroki, Masakado, Fumiya, Saito, Noriyuki, Sato, Yasuyoshi, Onoyama, Takumi, Nishida, Shu, Furuya, Genta, Katoh, Hiroto, Yamashita, Hiroharu, Kakimi, Kazuhiro, Seto, Yasuyuki, Ushiku, Tetsuo, Fukayama, Masashi, Ishikawa, Shumpei

“…Cancer histological images contain rich biological and clinical information, but quantitative representation can be problematic and has prevented the direct…”
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Genomic landscape of a mouse model of diffuse-type gastric adenocarcinoma by Zhang, Menghua, Sugita, Itsuki, Komura, Daisuke, Katoh, Hiroto, Shimada, Shu, Inazawa, Johji, Tanaka, Shinji, Ishikawa, Shumpei

“…Background There is a need for a model of diffuse-type gastric cancer that captures the features of the disease, facilitates the study of its mechanisms, and…”
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Identification of a Tumor Suppressor Relay between the FOXP3 and the Hippo Pathways in Breast and Prostate Cancers by WEIQUAN LI, LIZHONG WANG, KATOH, Hiroto, RUNHUA LIU, PAN ZHENG, YANG LIU

“…Defective expression of LATS2, a negative regulator of YAP oncoprotein, has been reported in cancer of prostate, breast, liver, brain, and blood origins…”
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Capturing the differences between humoral immunity in the normal and tumor environments from repertoire-seq of B-cell receptors using supervised machine learning by Konishi, Hiroki, Komura, Daisuke, Katoh, Hiroto, Atsumi, Shinichiro, Koda, Hirotomo, Yamamoto, Asami, Seto, Yasuyuki, Fukayama, Masashi, Yamaguchi, Rui, Imoto, Seiya, Ishikawa, Shumpei

“…The recent success of immunotherapy in treating tumors has attracted increasing interest in research related to the adaptive immune system in the tumor…”
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SegRep: Mask-Supervised Learning for Segment Representation in Pathology Images by Yang, Chichun, Komura, Daisuke, Ochi, Mieko, Kakiuchi, Miwako, Katoh, Hiroto, Ushiku, Tetsuo, Ishikawa, Shumpei

“…In pathology, various tissue and cell components play diverse biological roles. The morphology of each component can vary markedly with differentiation status…”
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Accumulation of Molecular Aberrations Distinctive to Hepatocellular Carcinoma Progression by Midorikawa, Yutaka, Yamamoto, Shogo, Tatsuno, Kenji, Renard-Guillet, Claire, Tsuji, Shingo, Hayashi, Akimasa, Ueda, Hiroki, Fukuda, Shiro, Fujita, Takanori, Katoh, Hiroto, Ishikawa, Shumpei, Covington, Kyle R, Creighton, Chad J, Sugitani, Masahiko, Wheeler, David A, Shibata, Tatsuhiro, Nagae, Genta, Takayama, Tadatoshi, Aburatani, Hiroyuki

“…Cancer develops through the accumulation of genetic and epigenetic aberrations. To identify sequential molecular alterations that occur during the development…”
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Somatic Single Hits Inactivate the X-Linked Tumor Suppressor FOXP3 in the Prostate by Wang, Lizhong, Liu, Runhua, Li, Weiquan, Chen, Chong, Katoh, Hiroto, Chen, Guo-Yun, McNally, Beth, Lin, Lin, Zhou, Penghui, Zuo, Tao, Cooney, Kathleen A., Liu, Yang, Zheng, Pan

“…Despite clear epidemiological and genetic evidence for X-linked prostate cancer risk, all prostate cancer genes identified are autosomal. Here, we report…”
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