Search Results - "Kato, Hideaki E"

Structure-Function Relationship of Channelrhodopsins by Kato, Hideaki E

“…Ion-translocating rhodopsins, especially channelrhodopsins (ChRs), have attracted broad attention as a powerful tool to modulate the membrane potential of…”
Get more information

Cortical layer-specific critical dynamics triggering perception by Marshel, James H, Kim, Yoon Seok, Machado, Timothy A, Quirin, Sean, Benson, Brandon, Kadmon, Jonathan, Raja, Cephra, Chibukhchyan, Adelaida, Ramakrishnan, Charu, Inoue, Masatoshi, Shane, Janelle C, McKnight, Douglas J, Yoshizawa, Susumu, Kato, Hideaki E, Ganguli, Surya, Deisseroth, Karl

“…Perceptual experiences may arise from neuronal activity patterns in mammalian neocortex. We probed mouse neocortex during visual discrimination using a…”
Get full text

Conformational transitions of a neurotensin receptor 1–Gi1 complex by Kato, Hideaki E., Zhang, Yan, Hu, Hongli, Suomivuori, Carl-Mikael, Kadji, Francois Marie Ngako, Aoki, Junken, Krishna Kumar, Kaavya, Fonseca, Rasmus, Hilger, Daniel, Huang, Weijiao, Latorraca, Naomi R., Inoue, Asuka, Dror, Ron O., Kobilka, Brian K., Skiniotis, Georgios

“…Neurotensin receptor 1 (NTSR1) is a G-protein-coupled receptor (GPCR) that engages multiple subtypes of G protein, and is involved in the regulation of blood…”
Get full text

Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT by Doki, Shintaro, Kato, Hideaki E., Solean, Nicolae, Iwaki, Masayo, Koyama, Michio, Hattori, Motoyuki, Iwase, Norihiko, Tsukazaki, Tomoya, Sugita, Yuji, Kandori, Hideki, Newstead, Simon, Ishitani, Ryuichiro, Nureki, Osamu

“…Proton-dependent oligopeptide transporters (POTs) are major facilitator superfamily (MFS) proteins that mediate the uptake of peptides and peptide-like…”
Get full text

Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex by Krishna Kumar, Kaavya, Shalev-Benami, Moran, Robertson, Michael J., Hu, Hongli, Banister, Samuel D., Hollingsworth, Scott A., Latorraca, Naomi R., Kato, Hideaki E., Hilger, Daniel, Maeda, Shoji, Weis, William I., Farrens, David L., Dror, Ron O., Malhotra, Sanjay V., Kobilka, Brian K., Skiniotis, Georgios

“…Cannabis elicits its mood-enhancing and analgesic effects through the cannabinoid receptor 1 (CB1), a G protein-coupled receptor (GPCR) that signals primarily…”
Get full text

Crystal structure of the channelrhodopsin light-gated cation channel by Kato, Hideaki E., Zhang, Feng, Yizhar, Ofer, Ramakrishnan, Charu, Nishizawa, Tomohiro, Hirata, Kunio, Ito, Jumpei, Aita, Yusuke, Tsukazaki, Tomoya, Hayashi, Shigehiko, Hegemann, Peter, Maturana, Andrés D., Ishitani, Ryuichiro, Deisseroth, Karl, Nureki, Osamu

“…Channelrhodopsins (ChRs) are light-gated cation channels derived from algae that have shown experimental utility in optogenetics; for example, neurons…”
Get full text

Endogenous ligand recognition and structural transition of a human PTH receptor by Kobayashi, Kazuhiro, Kawakami, Kouki, Kusakizako, Tsukasa, Miyauchi, Hirotake, Tomita, Atsuhiro, Kobayashi, Kan, Shihoya, Wataru, Yamashita, Keitaro, Nishizawa, Tomohiro, Kato, Hideaki E., Inoue, Asuka, Nureki, Osamu

“…Endogenous parathyroid hormone (PTH) and PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R) and activate the stimulatory G-protein…”
Get full text

Structural basis for Na+ transport mechanism by a light-driven Na+ pump by Kato, Hideaki E., Inoue, Keiichi, Abe-Yoshizumi, Rei, Kato, Yoshitaka, Ono, Hikaru, Konno, Masae, Hososhima, Shoko, Ishizuka, Toru, Hoque, Mohammad Razuanul, Kunitomo, Hirofumi, Ito, Jumpei, Yoshizawa, Susumu, Yamashita, Keitaro, Takemoto, Mizuki, Nishizawa, Tomohiro, Taniguchi, Reiya, Kogure, Kazuhiro, Maturana, Andrés D., Iino, Yuichi, Yawo, Hiromu, Ishitani, Ryuichiro, Kandori, Hideki, Nureki, Osamu

“…Krokinobacter eikastus rhodopsin 2 (KR2) is the first light-driven Na + pump discovered, and is viewed as a potential next-generation optogenetics tool. Since…”
Get full text

Crystal structure of the natural anion-conducting channelrhodopsin GtACR1 by Kim, Yoon Seok, Kato, Hideaki E., Yamashita, Keitaro, Ito, Shota, Inoue, Keiichi, Ramakrishnan, Charu, Fenno, Lief E., Evans, Kathryn E., Paggi, Joseph M., Dror, Ron O., Kandori, Hideki, Kobilka, Brian K., Deisseroth, Karl

“…The naturally occurring channelrhodopsin variant anion channelrhodopsin-1 (ACR1), discovered in the cryptophyte algae Guillardia theta , exhibits large…”
Get full text

Structural mechanisms of selectivity and gating in anion channelrhodopsins by Kato, Hideaki E., Kim, Yoon Seok, Paggi, Joseph M., Evans, Kathryn E., Allen, William E., Richardson, Claire, Inoue, Keiichi, Ito, Shota, Ramakrishnan, Charu, Fenno, Lief E., Yamashita, Keitaro, Hilger, Daniel, Lee, Soo Yeun, Berndt, Andre, Shen, Kang, Kandori, Hideki, Dror, Ron O., Kobilka, Brian K., Deisseroth, Karl

“…Both designed and natural anion-conducting channelrhodopsins (dACRs and nACRs, respectively) have been widely applied in optogenetics (enabling selective…”
Get full text

Role of Asn112 in a Light-Driven Sodium Ion-Pumping Rhodopsin by Abe-Yoshizumi, Rei, Inoue, Keiichi, Kato, Hideaki E, Nureki, Osamu, Kandori, Hideki

“…Light-driven outward sodium-pumping rhodopsin (NaR) was recently found in marine bacteria. Krokinobacter eikastus rhodopsin 2 (KR2) actively transports sodium…”
Get full text

The light-driven sodium ion pump: A new player in rhodopsin research by Kato, Hideaki E., Inoue, Keiichi, Kandori, Hideki, Nureki, Osamu

“…Rhodopsins are one of the most studied photoreceptor protein families, and ion‐translocating rhodopsins, both pumps and channels, have recently attracted broad…”
Get full text

Mutant of a Light-Driven Sodium Ion Pump Can Transport Cesium Ions by Konno, Masae, Kato, Yoshitaka, Kato, Hideaki E, Inoue, Keiichi, Nureki, Osamu, Kandori, Hideki

“…Krokinobacter eikastus rhodopsin 2 (KR2) is a light-driven Na+ pump found in marine bacterium. KR2 pumps Li+ and Na+, but it becomes an H+ pump in the presence…”
Get full text

Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK by Fukuda, Masahiro, Takeda, Hironori, Kato, Hideaki E., Doki, Shintaro, Ito, Koichi, Maturana, Andrés D., Ishitani, Ryuichiro, Nureki, Osamu

“…NarK belongs to the nitrate/nitrite porter (NNP) family in the major facilitator superfamily (MFS) and plays a central role in nitrate uptake across the…”
Get full text

Chimeras of Channelrhodopsin-1 and -2 from Chlamydomonas reinhardtii Exhibit Distinctive Light-induced Structural Changes from Channelrhodopsin-2 by Inaguma, Asumi, Tsukamoto, Hisao, Kato, Hideaki E., Kimura, Tetsunari, Ishizuka, Toru, Oishi, Satomi, Yawo, Hiromu, Nureki, Osamu, Furutani, Yuji

“…Channelrhodopsin-2 (ChR2) from the green alga Chlamydomonas reinhardtii functions as a light-gated cation channel that has been developed as an optogenetic…”
Get full text

Molecular Dynamics of Channelrhodopsin at the Early Stages of Channel Opening by Takemoto, Mizuki, Kato, Hideaki E, Koyama, Michio, Ito, Jumpei, Kamiya, Motoshi, Hayashi, Shigehiko, Maturana, Andrés D, Deisseroth, Karl, Ishitani, Ryuichiro, Nureki, Osamu

“…Channelrhodopsin (ChR) is a light-gated cation channel that responds to blue light. Since ChR can be readily expressed in specific neurons to precisely control…”
Get full text

Crystal structures of the TRIC trimeric intracellular cation channel orthologues by Kasuya, Go, Hiraizumi, Masahiro, Maturana, Andrés D, Kumazaki, Kaoru, Fujiwara, Yuichiro, Liu, Keihong, Nakada-Nakura, Yoshiko, Iwata, So, Tsukada, Keisuke, Komori, Tomotaka, Uemura, Sotaro, Goto, Yuhei, Nakane, Takanori, Takemoto, Mizuki, Kato, Hideaki E, Yamashita, Keitaro, Wada, Miki, Ito, Koichi, Ishitani, Ryuichiro, Hattori, Motoyuki, Nureki, Osamu

“…Ca^2＋ release from the sarcoplasmic reticulum （SR） and endoplasmic reticulum （ER） is crucial for muscle contrac- tion, cell growth, apoptosis, learning and…”
Get full text

Structure of the neurotensin receptor 1 in complex with β-arrestin 1 by Huang, Weijiao, Masureel, Matthieu, Qu, Qianhui, Janetzko, John, Inoue, Asuka, Kato, Hideaki E., Robertson, Michael J., Nguyen, Khanh C., Glenn, Jeffrey S., Skiniotis, Georgios, Kobilka, Brian K.

“…Arrestin proteins bind to active, phosphorylated G-protein-coupled receptors (GPCRs), thereby preventing G-protein coupling, triggering receptor…”
Get full text

Pump-like channelrhodopsins: Not just bridging the gap between ion pumps and ion channels by Kishi, Koichiro E., Kato, Hideaki E.

“…Channelrhodopsins are microbial rhodopsins that work as light-gated ion channels. Their importance has become increasingly recognized due to their ability to…”
Get full text

Structural insights into µ-opioid receptor activation by Huang, Weijiao, Manglik, Aashish, Venkatakrishnan, A. J., Laeremans, Toon, Feinberg, Evan N., Sanborn, Adrian L., Kato, Hideaki E., Livingston, Kathryn E., Thorsen, Thor S., Kling, Ralf C., Granier, Sébastien, Gmeiner, Peter, Husbands, Stephen M., Traynor, John R., Weis, William I., Steyaert, Jan, Dror, Ron O., Kobilka, Brian K.

“…Activation of the μ-opioid receptor (μOR) is responsible for the efficacy of the most effective analgesics. To shed light on the structural basis for μOR…”
Get full text