Search Results - "Katkar, Prafulla"

A natural anticancer agent thaspine targets human topoisomerase IB by Castelli, Silvia, Katkar, Prafulla, Vassallo, Oscar, Falconi, Mattia, Linder, Stig, Desideri, Alessandro

“…The different steps of the topoisomerase I catalytic cycle have been analyzed in the presence of the plant alkaloid thaspine (1-…”
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Comparative studies of oxindolimine-metal complexes as inhibitors of human DNA topoisomerase IB by Castelli, Silvia, Gonçalves, Marcos Brown, Katkar, Prafulla, Stuchi, Gabriela Cristina, Couto, Ricardo Alexandre Alves, Petrilli, Helena Maria, da Costa Ferreira, Ana Maria

“…Copper(II) and zinc(II) complexes with oxindolimine ligands, obtained by a condensation reaction between isatin (1H-indole-2,3-dione) and…”
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A derivative of the natural compound kakuol affects DNA relaxation of topoisomerase IB inhibiting the cleavage reaction by Castelli, Silvia, Vieira, Sara, D’Annessa, Ilda, Katkar, Prafulla, Musso, Loana, Dallavalle, Sabrina, Desideri, Alessandro

“…► A derivative of the natural compound kakuol is active against human topoisomerase. ► The compound inhibits the cleavage reaction during DNA relaxation. ►…”
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Inhibition of human DNA topoisomerase IB by a Cyclometalated Gold III compound: Analysis on the different steps of the enzyme catalytic cycle by Castelli, Silvia, Vassallo, Oscar, Katkar, Prafulla, Che, Chi-Ming, Sun, Raymond Wai-Yin, Desideri, Alessandro

“…► The Cyclometalated gold(III) compound efficiently inhibits human topoisomerase IB. ► The inhibition occurs through a mechanism different from camptothecin. ►…”
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Effect of oxindolimine copper(II) and zinc(II) complexes on human topoisomerase I activity by Katkar, Prafulla, Coletta, Andrea, Castelli, Silvia, Sabino, Gustavo L, Couto, Ricardo A Alves, Ferreira, Ana M da Costa, Desideri, Alessandro

“…The ability of oxindolimine copper(II) and zinc(II) complexes, known to have antitumor activity, to inhibit human topoisomerase IB has been tested through…”
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Effect of oxindolimine copper(ii) and zinc(ii) complexes on human topoisomerase I activityElectronic supplementary information (ESI) available. See DOI: 10.1039/c3mt00099k by Katkar, Prafulla, Coletta, Andrea, Castelli, Silvia, Sabino, Gustavo L, Couto, Ricardo A. Alves, da Costa Ferreira, Ana M, Desideri, Alessandro

“…The ability of oxindolimine copper( ii ) and zinc( ii ) complexes, known to have antitumor activity, to inhibit human topoisomerase IB has been tested through…”
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