Search Results - "Kathleen H. Mortell"
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Varying the Size of Multivalent Ligands: The Dependence of Concanavalin A Binding on Neoglycopolymer Length
Published in Journal of the American Chemical Society (15-10-1997)Get full text
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Recognition Specificity of Neoglycopolymers Prepared by Ring-Opening Metathesis Polymerization
Published in Journal of the American Chemical Society (06-03-1996)Get full text
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Synthesis of Cell Agglutination Inhibitors by Aqueous Ring-Opening Metathesis Polymerization
Published in Journal of the American Chemical Society (01-12-1994)Get full text
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Specificity of C-Glycoside Complexation by Mannose/Glucose Specific Lectins
Published in Biochemistry (Easton) (19-03-1996)“…The binding of the mannose/glucose specific lectins from Canavalia ensiformis (concanavalin A) and Dioclea grandiflora to a series of C-glucosides and…”
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(L)-Phenylglycine, but not necessarily other α2δ subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats
Published in Pain (Amsterdam) (01-11-2006)Get full text
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6
Structure–activity relationships of N-substituted ligands for the α7 nicotinic acetylcholine receptor
Published in Bioorganic & medicinal chemistry letters (2010)“…A series of α7 neuronal nicotinic acetylcholine receptor ligands were designed based on a structural combination of a potent, but non-selective ligand,…”
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Structure-activity relationships of α-amino acid ligands for the α2δ subunit of voltage-gated calcium channels
Published in Bioorganic & medicinal chemistry letters (01-03-2006)Get full text
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8
New Antibacterial tetrahydro-4(2 H)-thiopyran and thiomorpholine S-oxide and S, S-dioxide phenyloxazolidinones
Published in Bioorganic & medicinal chemistry letters (01-12-2003)“…Combinatorial libraries of N-acylated 5-( S)-aminomethyloxazolidinone derivatives of S-oxide and S, S-dioxide tetrahydro-4(2H)-thiopyranyl and thiomorpholine…”
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9
Structure-activity relationships of N-substituted ligands for the a7 nicotinic acetylcholine receptor
Published in Bioorganic & medicinal chemistry letters (01-01-2010)“…A series of a7 neuronal nicotinic acetylcholine receptor ligands were designed based on a structural combination of a potent, but non-selective ligand,…”
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10
Fetal Bovine Serum and Other Sera Used in Tissue Culture Increase Epithelial Permeability
Published in In Vitro Cellular & Developmental Biology - Animal (01-03-1993)“…Fetal bovine serum (FBS) or heat-inactivated FBS ($56\textdegree C$for 30 min, HFBS) caused a dose-dependent decrease in the transepithelial electrical…”
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( l)-Phenylglycine, but not necessarily other α 2δ subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats
Published in Pain (Amsterdam) (2006)“…Gabapentin and pregabalin have been demonstrated, both in animal pain models and clinically, to be effective analgesics particularly for the treatment of…”
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Journal Article -
12
Structure-activity relationships of N-substituted ligands for the alpha7 nicotinic acetylcholine receptor
Published in Bioorganic & medicinal chemistry letters (01-01-2010)“…A series of alpha7 neuronal nicotinic acetylcholine receptor ligands were designed based on a structural combination of a potent, but non-selective ligand,…”
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Journal Article -
13
Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels
Published in Bioorganic & medicinal chemistry letters (01-03-2006)“…A series of alpha-amino acids were identified as ligands which compete with gabapentin for binding to the alpha(2)delta subunit of voltage-dependent Ca(2+)…”
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14
Structure-activity relationships of alpha -amino acid ligands for the alpha sub(2) delta subunit of voltage-gated calcium channels
Published in Bioorganic & medicinal chemistry letters (01-01-2006)“…A series of alpha -amino acids were identified as ligands which compete with gabapentin for binding to the alpha sub(2) delta subunit of voltage-dependent Ca…”
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15
Structure–activity relationships of α-amino acid ligands for the α 2δ subunit of voltage-gated calcium channels
Published in Bioorganic & medicinal chemistry letters (2006)“…A series of α-amino acids were identified as ligands which compete with gabapentin for binding to the α 2δ subunit of voltage-dependent Ca 2+ channels. Potent…”
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16
Neoglycopolymers produced by aqueous ring-opening metathesis polymerization: decreasing saccharide density increases activity
Published in Journal of molecular catalysis. A, Chemical (24-02-1997)“…Non-natural carbohydrate-bearing polymers are emerging as important materials for the investigation of multivalent carbohydrate-protein interactions. In the…”
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Interaction of neoglycopolymers produced by aqueous ROMP with a carbohydrate-binding protein
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Dissertation -
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(L)-Phenylglycine, but not necessarily other alpha2delta subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats
Published in Pain (Amsterdam) (01-11-2006)“…Gabapentin and pregabalin have been demonstrated, both in animal pain models and clinically, to be effective analgesics particularly for the treatment of…”
Get full text
Journal Article -
20
Interaction of neoglycopolymers produced by aqueous ROMP with a carbohydrate-binding protein
Published 01-01-1997“…This dissertation describes the production of a new class of carbohydrate-substituted polymers via an aqueous ring-opening metathesis polymerization (ROMP) and…”
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Dissertation