Search Results - "Kathem, Sarmed H."

Ciliotherapy: Remote Control of Primary Cilia Movement and Function by Magnetic Nanoparticles by Pala, Rajasekharreddy, Mohieldin, Ashraf M, Sherpa, Rinzhin T, Kathem, Sarmed H, Shamloo, Kiumars, Luan, Zhongyue, Zhou, Jing, Zheng, Jian-Guo, Ahsan, Amir, Nauli, Surya M

“…Patients with polycystic kidney disease (PKD) are characterized with uncontrolled hypertension. Hypertension in PKD is a ciliopathy, an abnormal function…”
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Personalized Nanotherapy by Specifically Targeting Cell Organelles To Improve Vascular Hypertension by Pala, Rajasekharreddy, Mohieldin, Ashraf M, Shamloo, Kiumars, Sherpa, Rinzhin T, Kathem, Sarmed H, Zhou, Jing, Luan, Zhongyue, Zheng, Jian-Guo, Ahsan, Amir, Nauli, Surya M

“…Ciliopathies caused by abnormal function of primary cilia include expanding spectrum of kidney, liver, and cardiovascular disorders. There is currently no…”
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Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway by Kathem, Sarmed H, Nasrawi, Yasameen Sh, Mutlag, Shihab H, Nauli, Surya M

“…The human gastrointestinal system is a complex ecosystem crucial for well-being. During sepsis-induced gut injury, the integrity of the intestinal barrier can…”
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Thymoquinone Attenuates Immune Mediated Liver Injury Induced by Concanavalin A in Mice by Ahmad, Halla A., H. Kathem, Sarmed

“…Autoimmune hepatitis is an inflammatory disease and its incidence has been increasing. The features of hepatitis are the release of inflammatory cytokines, the…”
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Mentha piperita Oil Exerts an Antiepileptic Effect in Pilocarpine and Pentylenetetrazol-Induced Seizures in Mice by Abdulsahib, Waleed K., Kathem, Sarmed H., Al-Radeef, Mohanad Y., Jasim, Layth S.

“…Introduction. Epilepsy is a progressive, chronic neurological disorder characterized by recurrent seizures. Peppermint (Mentha piperita L.) (MP) is one of the…”
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Berbamine and thymoquinone exert protective effects against immune-mediated liver injury via NF-κB dependent pathway by Kathem, Sarmed H., Abdulsahib, Waleed K., Zalzala, Munaf H.

“…Background Immune-mediated hepatitis is a severe impendence to human health, and no effective treatment is currently available. Therefore, new, safe, low-cost…”
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Carvone Attenuates Irinotecan-Induced Intestinal Mucositis and Diarrhea in Mice by Abbas, Ban Walid, H. Kathem, Sarmed

“…Intestinal mucositis is referring to inflammatory or ulcerative lesions of the oral or gastrointestinal tract; one of the main reasons is treatment with cancer…”
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Measuring depression and anxiety prevalence among Iraqi healthcare college students using hospital anxiety and depression scale by Kathem, Sarmed H., Al Jumaili, Ali A., Noor-Aldeen, Malak, Najah, Noor, Ali Khalid, Dema

“…Objective: The study aimed to 1) measure the prevalence of depression and anxiety among Iraqi pharmacy and medical students at a number of universities in…”
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Roles of dopamine receptor on chemosensory and mechanosensory primary cilia in renal epithelial cells by Upadhyay, Viralkumar S, Muntean, Brian S, Kathem, Sarmed H, Hwang, Jangyoun J, Aboualaiwi, Wissam A, Nauli, Surya M

“…Dopamine plays a number of important physiological roles. However, activation of dopamine receptor type-5 (DR5) and its effect in renal epithelial cells have…”
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The Roles of Primary cilia in Polycystic Kidney Disease by Kathem, Sarmed H, Mohieldin, Ashraf M, Nauli, Surya M

“…Autosomal dominant polycystic kidney disease (ADPKD) is an inherited genetic disorder that results in progressive renal cyst formation with ultimate loss of…”
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Dopaminergic signaling within the primary cilia in the renovascular system by Atkinson, Kimberly F, Kathem, Sarmed H, Jin, Xingjian, Muntean, Brian S, Abou-Alaiwi, Wissam A, Nauli, Andromeda M, Nauli, Surya M

“…Activation of dopamine receptor type-5 (DR5) has been known to reduce systemic blood pressure, most likely by increasing renal vasodilation and enhancing…”
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Gentiopicroside ameliorates acute inflammatory kidney injury in a mouse model induced by LPS through hampering NF‐κB, AP‐1 and IRF3 pathways by Shareef, Saja M., Kathem, Sarmed H.

“…Background Acute kidney injury (AKI) is one of the most critical care conditions with various etiologies and high mortality. LPS induces AKI by activation of…”
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Citronellol exerts lung protective and anti‐inflammatory effects through hampering NF‐κB in lipopolysaccharide‐induced acute lung injury in mice by Redha, Samah M., Kathem, Sarmed H.

“…Background Acute lung injury (ALI) is one of the most serious conditions characterized by an exacerbation of inflammatory response in the lungs that can result…”
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Ciliotherapy： a novel intervention in polycystic kidney disease by Kathem, Sarmed H, Mohieldin, Ashraf M, Abdul-Majeed, Shakila, Ismail, Sajida H, Altaei, Qaiss H, Alshimmari, Ibrahim K, Alsaidi, Mohanned M, Khammas, Hussein, Nauli, Andromeda M, Joe, Bina, Nauli, Surya M

“…Background Ciliopathies are a group of diseases associated with abnormal structure or function of primary cilia. Ciliopathies include polycystic kidney disease…”
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The Protective Effect of Ethanolic Extract of Mentha spicata Against Irinotecan-Induced Mucositis in mice by Abdul jabbar, Aliaa Abdul sattar, H. Kathem, Sarmed

“…Irinotecan induced-mucositis is an inflammatory event of intestine caused by an increase in concentration of active metabolite 7­ethyl­10-hydroxycamptothecin…”
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Sudden Transition of Pharmacy Education from Traditional to Distance Learning in the Era of COVID-19: Action Steps of a Leading Pharmacy School in Iraq by Ahmed, Kawther K., Salman, Salema S., A. Abbas, Wafaa, Alkaisy, Shahad W., Kathem, Sarmed H.

“…Education around the world has been negatively affected by the new coronavirus disease (COVID-19) pandemic. Many institutions had to transition to distance…”
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Evaluation of the Possible Immuno-Protective Effect of Nigella Sativa Seed Oil on Cyclophosphamide- Induced Myelosuppression in Mice by Alsaad, Shahad A., Kathem, Sarmed H.

“…Myelosuppression is one of the serious adverse effects of cancer chemotherapy that lead to life threatening febrile neutropenia and considered a limiting…”
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Prevalence of UGT1A193 and ABCC5 Polymorphisms in Cancer Patients Receiving Irinotecan-Based Chemotherapy at Al-Najaf Al-Ashraf by Al_talkani, Ahmed F., H. Kathem, Sarmed

“…Irinotecan (CPT-11) is a semisynthetic derivative of the antineoplastic agent camptothecin used in a wide range as an anti-cancer agent in many solid tumors…”
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Farnesoid X Receptor is an Exciting New Perspective Target For Treatment Of Diverse Pathological Disorders: Review by Al-khfajy, Wrood S, Kathem, Sarmed H, Aboddy, Amani Anees, Hatem, Suhad Faisal, Zalzala, Munaf H, Arif, Inam Sameh

“…[...]clinical trials with selective FXR agonists/ antagonist should shed more light on the precise role of this receptor in diverse pathological disorders…”
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Nigella Sativa Seed Oil Effectively Attenuates Cyclophosphamide‐Induced Myelosuppression in Mice by Saad, Shahad Ammar, Kathem, Sarmed H.

“…Abstract only Myelosuppression is one of the serious adverse effects of cancer chemotherapy that lead to life threatening febrile neutropenia and considered a…”
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