Search Results - "Kate Navaratnam"

Platelet response to aspirin in UK and Irish pregnancy cohorts: a genome-wide approach by Mone, Fionnuala, Gupta, Juhi K., Phelan, Marie M., Meher, Shireen, Lian, Lu Yung, Francis, Ben, Zhang, Eunice, Mulcahy, Cecilia, Alfirevic, Ana, Mcauliffe, Fionnuala M., Navaratnam, Kate

“…A multi-center prospective cross-sectional and genome-wide association study (GWAS) recruited pregnant women taking low dose aspirin. Objectives were to (i)…”
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Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort by Maher, Gillian M, Kenny, Louise C, Navaratnam, Kate, Alfirevic, Zarko, Sheehan, Darina, Baker, Philip N, Gluud, Christian, Tuytten, Robin, Kublickas, Marius, Niklasson, Boel, Duvekot, Johannes J, van den Berg, Caroline B, Wu, Pensee, Kublickiene, Karolina, McCarthy, Fergus P, Khashan, Ali S

“…Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to enable the…”
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Amniocentesis and chorionic villus sampling for prenatal diagnosis by Alfirevic, Zarko, Navaratnam, Kate, Mujezinovic, Faris

“…During pregnancy, fetal cells suitable for genetic testing can be obtained from amniotic fluid by amniocentesis (AC), placental tissue by chorionic villus…”
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Anti‐Infective Dosing in Special Populations: Pregnancy by Hazenberg, Phoebe, Navaratnam, Kate, Busuulwa, Paula, Waitt, Catriona

“…Substantial anatomical and physiological changes occur during pregnancy and labor, which impact on drug absorption, distribution, metabolism, and elimination…”
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Aspirin non-responsiveness in pregnant women at high-risk of pre-eclampsia by Navaratnam, Kate, Alfirevic, Ana, Jorgensen, Andrea, Alfirevic, Zarko

“…Low-dose aspirin is recommended for prevention of pre-eclampsia in high-risk pregnant women. Current doses provide a conservative risk reduction and some…”
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Investigation and management of the small for gestational age fetus by Bullough, Siân, Navaratnam, Kate, Sharp, Andrew

“…The desire to identify the small for gestational age fetus is due to its association with stillbirth and poorer neonatal outcomes. The difficulty lies in…”
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Prenatal screening and diagnosis in multiple pregnancies by Gent, Joanna, Navaratnam, Kate, Sharp, Andrew

“…Multiple pregnancies account for 1.5% of pregnancies in the UK and both aneuploidies and structural anomalies occur more frequently in twins, compared to…”
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How important is aspirin adherence when evaluating effectiveness of low-dose aspirin? by Navaratnam, Kate, Alfirevic, Zarko, Pirmohamed, Munir, Alfirevic, Ana

“…Low-dose aspirin (LDA) is advocated for women at high-risk of pre-eclampsia, providing a modest, 10%, reduction in risk. Cardiology meta-analyses demonstrate…”
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Aromatase inhibitors for uterine fibroids by Song, Huan, Lu, DongHao, Navaratnam, Kate, Shi, Gang

“…Uterine fibroids, also called uterine leiomyomas or myomas, are the most common benign tumours in women of reproductive age. Albeit generally benign, uterine fi…”
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Non‐immune hydrops fetalis: a practical guide for obstetricians by Khairudin, Delima, Alfirevic, Zarko, Mone, Fionnuala, Navaratnam, Kate

“…Key content Hydrops fetalis is the accumulation of two or more fetal fluid collections, including pericardial effusion, pleural effusion(s), ascites and skin…”
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Labour induction with prostaglandins: a systematic review and network meta-analysis by Alfirevic, Zarko, Keeney, Edna, Dowswell, Therese, Welton, Nicky J, Dias, Sofia, Jones, Leanne V, Navaratnam, Kate, Caldwell, Deborah M

“…Objectives To assess the effectiveness and safety of prostaglandins used for labour induction.Design Systematic review with Bayesian network meta-analysisData…”
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Provision of obstetrics and gynaecology services during the COVID‐19 pandemic: a survey of junior doctors in the UK National Health Service by Rimmer, MP, Al Wattar, BH, Barlow, Catriona, Black, Naomi, Carpenter, Ciara, Conti‐Ramsden, Frances, Dalton, John A W, Davies, Rhianna, Davies, Rebecca, Dunlop, Cheryl, Guyett, Elvena, Jamison, Laura, Karavadra, Babu, Kasaven, Lorraine, Lattey, Katherine, Long, Emma, Macmahon, Caroline, Navaratnam, Kate, Nijjar, Simrit, O'Brien, Stephen, Ojukwu, Obi, Parnell, Laura, Raglan, Olivia, Ramcharn, Meera, Riches, Jenny, Stocker, Linden Jane, Wong, Siew Chee, Wyeth, Charlotte

“…Objective The coronavirus disease 2019 (COVID‐19) pandemic is disrupting health services worldwide. We aimed to evaluate the provision of obstetrics and…”
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Evaluation of agreement of placental growth factor (PlGF) tests and the soluble FMS-like tyrosine kinase 1 (sFlt-1)/PlGF ratio, comparison of predictive accuracy for pre-eclampsia, and relation to uterine artery Doppler and response to aspirin by Navaratnam, Kate, Abreu, Patricia, Clarke, Helen, Jorgensen, Andrea, Alfirevic, Ana, Alfirevic, Zarko

“…Objectives: The objective of this study is to evaluate agreement between PlGF and sFlt-1/PlGF ratio tests and compare their predictive accuracy for…”
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Does advanced operative obstetrics still have a place in contemporary practice? by Tempest, Nicola, Navaratnam, Kate, Hapangama, Dharani Kosala

“…This article reviews recent significant contributions to the literature concerning advanced operative obstetric procedures used for rotational vaginal…”
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Assessing measures of aspirin adherence in pregnancy: Secondary analysis of the TEST randomized controlled trial by Mone, Fionnuala, Mulcahy, Cecilia, Navaratnam, Kate, Phelan, Marie M., Breathnach, Fionnuala, Alfirevic, Ana, McAuliffe Frcog, Fionnuala M.

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Foetal loss after chorionic villus sampling and amniocentesis in twin pregnancies: A multicentre retrospective cohort study by Navaratnam, Kate, Khairudin, Delima, Chilton, Robyn, Sharp, Andrew, Attilakos, George, Stott, Daniel, Relph, Sophie, Spencer, Rebecca, Badr, Dominique A., Carlin, Andrew, Jani, Jacques, Kilby, Mark D., Sebghati, Mercede, Khalil, Asma, Alfirevic, Zarko

“…Objective We aimed to determine foetal losses for DCDA and MCDA twins following transabdominal CVS or amniocentesis performed <22+0 weeks. Methods…”
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Short versus Standard Mifepristone and Misoprostol Regimen for Second- and Third-Trimester Termination of Pregnancy for Fetal Anomaly by Sharp, Andrew, Navaratnam, Kate, Abreu, Patricia, Alfirevic, Zarko

“…Termination of pregnancy requires a 48-hour 'window' between mifepristone and misoprostol. Shorter durations have been used in first-trimester termination, but…”
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Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort [version 3; peer review: 2 approved] by Kate Navaratnam, Louise C. Kenny, Darina Sheehan, Zarko Alfirevic, Christian Gluud, Philip N. Baker, Marius Kublickas, Robin Tuytten, Johannes J. Duvekot, Boel Niklasson, Pensee Wu, Caroline B. van den Berg, Ali S. Khashan, Karolina Kublickiene, Gillian M. Maher, Fergus P. McCarthy

“…Background Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to…”
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Platelet Function and Response to Low-Dose Aspirin in Pregnancy by Navaratnam, Kate

“…Pre-eclampsia is a serious multisystem disorder unique to pregnant women and associated with significant maternal and perinatal morbidity and mortality…”
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Cohort profile: Improved Pregnancy Outcomes via Early Detection (IMPROvED), an International Multicentre Prospective Cohort by Maher, Gillian M., Kenny, Louise C., Navaratnam, Kate, Alfirevic, Zarko, Sheehan, Darina, Baker, Philip N., Gluud, Christian, Tuytten, Robin, Kublickas, Marius, Niklasson, Boel, Duvekot, Johannes J., van den Berg, Caroline B., Wu, Pensee, Kublickiene, Karolina, McCarthy, Fergus P., Khashan, Ali S.

“…Background Improved Pregnancy Outcomes via Early Detection (IMPROvED) is a multi-centre, European phase IIa clinical study. The primary aim of IMPROvED is to…”
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