Search Results - "Kate, Mara ten"

Early- and Late-Onset Depression in Late Life: A Prospective Study on Clinical and Structural Brain Characteristics and Response to Electroconvulsive Therapy by Dols, Annemiek, M.D., Ph.D, Bouckaert, Filip, M.D, Sienaert, Pascal, M.D., Ph.D, Rhebergen, Didi, M.D., Ph.D, Vansteelandt, Kristof, Ph.D, ten Kate, Mara, M.D, de Winter, Francois-Laurent, M.D, Comijs, Hannie C., Ph.D, Emsell, Louise, Ph.D, Oudega, Mardien L., M.D, van Exel, Eric, M.D., Ph.D, Schouws, Sigfried, Ph.D, Obbels, Jasmien, M.Sc, Wattjes, Mike, M.D., Ph.D, Barkhof, Frederik, M.D., Ph.D, Eikelenboom, Piet, M.D., Ph.D, Vandenbulcke, Mathieu, M.D., Ph.D, Stek, Max L., M.D., Ph.D

“…Objective The clinical profile of late-life depression (LLD) is frequently associated with cognitive impairment, aging-related brain changes, and somatic…”
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Gray matter network disruptions and amyloid beta in cognitively normal adults by Tijms, Betty M, Kate, Mara ten, Wink, Alle Meije, Visser, Pieter Jelle, Ecay, Mirian, Clerigue, Montserrat, Estanga, Ainara, Garcia Sebastian, Maite, Izagirre, Andrea, Villanua, Jorge, Martinez Lage, Pablo, van der Flier, Wiesje M, Scheltens, Philip, Sanz Arigita, Ernesto, Barkhof, Frederik

“…Abstract Gray matter networks are disrupted in Alzheimer's disease (AD). It is unclear when these disruptions start during the development of AD. Amyloid beta…”
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Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset by Hong, Shengjun, Prokopenko, Dmitry, Dobricic, Valerija, Kilpert, Fabian, Bos, Isabelle, Vos, Stephanie J. B., Tijms, Betty M., Andreasson, Ulf, Blennow, Kaj, Vandenberghe, Rik, Cleynen, Isabelle, Gabel, Silvy, Schaeverbeke, Jolien, Scheltens, Philip, Teunissen, Charlotte E., Niemantsverdriet, Ellis, Engelborghs, Sebastiaan, Frisoni, Giovanni, Blin, Olivier, Richardson, Jill C., Bordet, Regis, Molinuevo, José Luis, Rami, Lorena, Kettunen, Petronella, Wallin, Anders, Lleó, Alberto, Sala, Isabel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Dobson, Richard J. B., Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Wittig, Michael, Franke, Andre, Tanzi, Rudolph E., Visser, Pieter Jelle, Bertram, Lars

“…Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder and the most common form of dementia in the elderly. Susceptibility to AD is…”
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Assessing Amyloid Pathology in Cognitively Normal Subjects Using 18F-Flutemetamol PET: Comparing Visual Reads and Quantitative Methods by Collij, Lyduine E, Konijnenberg, Elles, Reimand, Juhan, ten Kate, Mara, den Braber, Anouk, Alves, Isadora Lopes, Zwan, Marissa, Yaqub, Maqsood, van Assema, Daniëlle ME, Wink, Alle Meije, Lammertsma, Adriaan A, Scheltens, Philip, Visser, Pieter Jelle, Barkhof, Frederik, van Berckel, Bart NM

“…Our objective was to determine the optimal approach for assessing amyloid disease in a cognitively normal elderly population. Methods: Dynamic 18F-flutemetamol…”
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White matter microstructure disruption in early stage amyloid pathology by Collij, Lyduine E., Ingala, Silvia, Top, Herwin, Wottschel, Viktor, Stickney, Kristine E., Tomassen, Jori, Konijnenberg, Elles, ten Kate, Mara, Sudre, Carole, Lopes Alves, Isadora, Yaqub, Maqsood M., Wink, Alle Meije, Van ‘t Ent, Dennis, Scheltens, Philip, Berckel, Bart N.M., Visser, Pieter Jelle, Barkhof, Frederik, Braber, Anouk Den

“…Introduction Amyloid beta (Aβ) accumulation is the first pathological hallmark of Alzheimer's disease (AD), and it is associated with altered white matter (WM)…”
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Optical coherence tomography angiography in preclinical Alzheimer's disease by van de Kreeke, Jacoba Alida, Nguyen, Hoang-Ton, Konijnenberg, Elles, Tomassen, Jori, den Braber, Anouk, Ten Kate, Mara, Yaqub, Maqsood, van Berckel, Bart, Lammertsma, Adriaan A, Boomsma, Dorret I, Tan, Stevie H, Verbraak, Frank, Visser, Pieter Jelle

“…As a protrusion from the brain, the retina might reflect the status of the brain. Previous studies showed a decrease in vessel density and foveal avascular…”
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24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial by Soininen, Hilkka, Solomon, Alina, Visser, Pieter Jelle, Hendrix, Suzanne B, Blennow, Kaj, Kivipelto, Miia, Hartmann, Tobias, Hallikainen, Ilona, Hallikainen, Merja, Helisalmi, Seppo, Lappalainen, Tarja, Liu, Yawu, Paajanen, Teemu, Wahlund, Lars-Olof, Freund-Levi, Yvonne, Andreasen, Niels, Hagman, Göran, Lindblom, Stina, Fassbender, Klaus, Riemenschneider, Matthias, Grimm, Marcus OW, Klees-Rollmann, Aline, Luley, Maxine, Lyros, Epameinondas, Schomburg, Robert, Kennel, Jennifer, Ramelli, Daniela, Frölich, Lutz, Hausner, Lucrezia, Laske, Christoph, Leyhe, Thomas, Mychajliw, Christian, Koehler, Niklas, Schiekofer, Stephan, Klünemann, Hans, Schröder, Johannes, Lütjohann, Dieter, Scheltens, Philip, van Rossum, Ineke, Scheltens, Nienke, Bertens, Daniela, ten Kate, Mara, Barkhof, Frederik, Henselmans, Johanna ML, Roks, Gerwin, van Hees, Anneke MJ, Ellison, Noel

“…Nutrition is an important modifiable risk factor in Alzheimer's disease. Previous trials of the multinutrient Fortasyn Connect showed benefits in mild…”
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Successful treatment of respiratory failure in Hirayama disease by Sol, Nik, Hartman, Joost, Ten Kate, Mara, van Kempen, Zoé, van der Kooi, Anneke, Vandertop, Peter, Tuinman, Pieter-Roel, van Oosten, Bob

“…Hirayama disease is a self-limiting cervical motor neuron disease, usually affecting the spinal cord at level C7-T1. We share an unusual case of Hirayama…”
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Genetic, vascular and amyloid components of cerebral blood flow in a preclinical population by Padrela, Beatriz E, Lorenzini, Luigi, Collij, Lyduine E, García, David Vállez, Coomans, Emma, Ingala, Silvia, Tomassen, Jori, Deckers, Quinten, Shekari, Mahnaz, Geus, Eco JC de, van de Giessen, Elsmarieke, Kate, Mara ten, Visser, Pieter Jelle, Barkhof, Frederik, Petr, Jan, Braber, Anouk den, Mutsaerts, Henk JMM

“…Aging-related cognitive decline can be accelerated by a combination of genetic factors, cardiovascular and cerebrovascular dysfunction, and amyloid-β burden…”
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Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort by Kim, Min, Snowden, Stuart, Suvitaival, Tommi, Ali, Ashfaq, Merkler, David J., Ahmad, Tahmina, Westwood, Sarah, Baird, Alison, Proitsi, Petroula, Nevado-Holgado, Alejo, Hye, Abdul, Bos, Isabelle, Vos, Stephanie, Vandenberghe, Rik, Teunissen, Charlotte, ten Kate, Mara, Scheltens, Philip, Gabel, Silvy, Meersmans, Karen, Blin, Olivier, Richardson, Jill, De Roeck, Ellen, Sleegers, Kristel, Bordet, Régis, Rami, Lorena, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Sala, Isabel, Lléo, Alberto, Peyratout, Gwendoline, Tainta, Mikel, Johannsen, Peter, Freund-Levi, Yvonne, Frölich, Lutz, Dobricic, Valerija, Engelborghs, Sebastiaan, Frisoni, Giovanni B., Molinuevo, José L., Wallin, Anders, Popp, Julius, Martinez-Lage, Pablo, Bertram, Lars, Barkhof, Frederik, Ashton, Nicholas, Blennow, Kaj, Zetterberg, Henrik, Streffer, Johannes, Visser, Pieter J., Lovestone, Simon, Legido-Quigley, Cristina

“…A critical and as-yet unmet need in Alzheimer's disease (AD) is the discovery of peripheral small molecule biomarkers. Given that brain pathology precedes…”
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Onset of Preclinical Alzheimer Disease in Monozygotic Twins by Konijnenberg, Elles, Tomassen, Jori, Braber, Anouk, Kate, Mara, Yaqub, Maqsood, Mulder, Sandra D., Nivard, Michel G., Vanderstichele, Hugo, Lammertsma, Adriaan A., Teunissen, Charlotte E., Berckel, Bart N. M., Boomsma, Dorret I., Scheltens, Philip, Tijms, Betty M., Visser, Pieter Jelle

“…Objective The present work was undertaken to study the genetic contribution to the start of Alzheimer's disease (AD) with amyloid and tau biomarkers in…”
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Retinal layer thickness in preclinical Alzheimer's disease by Kreeke, Jacoba A., Nguyen, Hoang‐Ton, Haan, Jurre, Konijnenberg, Elles, Tomassen, Jori, Braber, Anouk, Kate, Mara, Collij, Lyduine, Yaqub, Maqsood, Berckel, Bart, Lammertsma, Adriaan A., Boomsma, Dorret I., Tan, Hendra Stevie, Verbraak, Frank D., Visser, Pieter Jelle

“…Purpose There is urgent need for non‐invasive diagnostic biomarkers in the preclinical phase of Alzheimer's Disease (AD). Several studies suggest that retinal…”
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Cerebral blood flow, amyloid burden, and cognition in cognitively normal individuals by Ebenau, Jarith L., Visser, Denise, Verfaillie, Sander C. J., Timmers, Tessa, van Leeuwenstijn, Mardou S. S. A., Kate, Mara ten, Windhorst, Albert D., Barkhof, Frederik, Scheltens, Philip, Prins, Niels D., Boellaard, Ronald, van der Flier, Wiesje M., van Berckel, Bart N. M.

“…Purpose The role of cerebral blood flow (CBF) in the early stages of Alzheimer’s disease is complex and largely unknown. We investigated cross-sectional and…”
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Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay by Shi, Liu, Westwood, Sarah, Baird, Alison L., Winchester, Laura, Dobricic, Valerija, Kilpert, Fabian, Hong, Shengjun, Franke, Andre, Hye, Abdul, Ashton, Nicholas J., Morgan, Angharad R., Bos, Isabelle, Vos, Stephanie J.B., Buckley, Noel J., Kate, Mara ten, Scheltens, Philip, Vandenberghe, Rik, Gabel, Silvy, Meersmans, Karen, Engelborghs, Sebastiaan, De Roeck, Ellen E., Sleegers, Kristel, Frisoni, Giovanni B., Blin, Olivier, Richardson, Jill C., Bordet, Régis, Molinuevo, José L., Rami, Lorena, Wallin, Anders, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Lleó, Alberto, Alcolea, Daniel, Popp, Julius, Peyratout, Gwendoline, Martinez-Lage, Pablo, Tainta, Mikel, Johannsen, Peter, Teunissen, Charlotte E., Freund-Levi, Yvonne, Frölich, Lutz, Legido-Quigley, Cristina, Barkhof, Frederik, Blennow, Kaj, Zetterberg, Henrik, Baker, Susan, Morgan, B. Paul, Streffer, Johannes, Visser, Pieter Jelle, Bertram, Lars, Lovestone, Simon, Nevado-Holgado, Alejo J.

“…Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention…”
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Disease trajectories in behavioural variant frontotemporal dementia, primary psychiatric and other neurodegenerative disorders presenting with behavioural change by Reus, Lianne M., Vijverberg, Everard GB, Tijms, Betty M., Kate, Mara ten, Gossink, Flora, Krudop, Welmoed A., Campo, Marta del, Teunissen, Charlotte E., Barkhof, Frederik, van der Flier, Wiesje M., Visser, Pieter Jelle, Dols, Annemiek, Pijnenburg, Yolande AL

“…Behavioural variant frontotemporal dementia (bvFTD) is characterized by behavioural and social cognitive disturbances, while various psychiatric and…”
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The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics by Bos, Isabelle, Vos, Stephanie, Vandenberghe, Rik, Scheltens, Philip, Engelborghs, Sebastiaan, Frisoni, Giovanni, Molinuevo, José Luis, Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez-Lage, Pablo, Baird, Alison, Dobson, Richard, Legido-Quigley, Cristina, Sleegers, Kristel, Van Broeckhoven, Christine, Bertram, Lars, Ten Kate, Mara, Barkhof, Frederik, Zetterberg, Henrik, Lovestone, Simon, Streffer, Johannes, Visser, Pieter Jelle

“…There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer's disease (AD) in the predementia stages and to predict the rate of decline…”
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Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer’s disease CSF profile of neuronal injury and inflammation by Neumann, Alexander, Küçükali, Fahri, Bos, Isabelle, Vos, Stephanie J. B., Engelborghs, Sebastiaan, De Pooter, Tim, Joris, Geert, De Rijk, Peter, De Roeck, Ellen, Tsolaki, Magda, Verhey, Frans, Martinez-Lage, Pablo, Tainta, Mikel, Frisoni, Giovanni, Blin, Oliver, Richardson, Jill, Bordet, Régis, Scheltens, Philip, Popp, Julius, Peyratout, Gwendoline, Johannsen, Peter, Frölich, Lutz, Vandenberghe, Rik, Freund-Levi, Yvonne, Streffer, Johannes, Lovestone, Simon, Legido-Quigley, Cristina, ten Kate, Mara, Barkhof, Frederik, Strazisar, Mojca, Zetterberg, Henrik, Bertram, Lars, Visser, Pieter Jelle, van Broeckhoven, Christine, Sleegers, Kristel

“…Alzheimer’s disease (AD) biomarkers represent several neurodegenerative processes, such as synaptic dysfunction, neuronal inflammation and injury, as well as…”
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Longitudinal retinal layer changes in preclinical Alzheimer’s disease by Kreeke, Jacoba A., Nguyen, Hoang Ton, Konijnenberg, Elles, Tomassen, Jori, Braber, Anouk, Kate, Mara, Yaqub, Maqsood, Berckel, Bart, Lammertsma, Adriaan A., Boomsma, Dorret I., Tan, H. Stevie, Visser, Pieter Jelle, Verbraak, Frank D.

“…Purpose Several studies found reduced retinal thickness on optical coherence tomography (OCT) in Alzheimer’s disease (AD), even in preclinical stages,…”
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Paired plasma lipidomics and proteomics analysis in the conversion from mild cognitive impairment to Alzheimer's disease by Gómez-Pascual, Alicia, Naccache, Talel, Xu, Jin, Hooshmand, Kourosh, Wretlind, Asger, Gabrielli, Martina, Lombardo, Marta Tiffany, Shi, Liu, Buckley, Noel J., Tijms, Betty M., Vos, Stephanie J.B., ten Kate, Mara, Engelborghs, Sebastiaan, Sleegers, Kristel, Frisoni, Giovanni B., Wallin, Anders, Lleó, Alberto, Popp, Julius, Martinez-Lage, Pablo, Streffer, Johannes, Barkhof, Frederik, Zetterberg, Henrik, Visser, Pieter Jelle, Lovestone, Simon, Bertram, Lars, Nevado-Holgado, Alejo J., Gualerzi, Alice, Picciolini, Silvia, Proitsi, Petroula, Verderio, Claudia, Botía, Juan A., Legido-Quigley, Cristina

“…Alzheimer's disease (AD) is a neurodegenerative condition for which there is currently no available medication that can stop its progression. Previous studies…”
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Impact of APOE- epsilon 4 and family history of dementia on gray matter atrophy in cognitively healthy middle-aged adults by Kate, Mara ten, Sanz-Arigita, Ernesto J, Tijms, Betty M, Wink, Alle Meije, Clerigue, Montserrat, Garcia-Sebastian, Maite, Izagirre, Andrea, Ecay-Torres, Miriam, Estanga, Ainara, Villanua, Jorge, Vrenken, Hugo, Visser, Pieter Jelle, Martinez-Lage, Pablo, Barkhof, Frederik

“…The apolipoprotein E epsilon 4 allele (APOE4) and family history of dementia (FH) are well-known risk factors for the development of sporadic Alzheimer's…”
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