Search Results - "Katchur, Steven R."

Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function by Tian, Gaochao, Katchur, Steven R., Jiang, Yong, Briand, Jacques, Schaber, Michael, Kreatsoulas, Constantine, Schwartz, Benjamin, Thrall, Sara, Davis, Alicia M., Duvall, Sam, Kaufman, Brett A., Rumsey, William L.

“…8-Oxoguanine DNA glycosylase (OGG1) initiates base excision repair of the oxidative DNA damage product 8-oxoguanine. OGG1 is bifunctional; catalyzing glycosyl…”
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Enhanced mitochondrial DNA repair of the common disease-associated variant, Ser326Cys, of hOGG1 through small molecule intervention by Baptiste, Beverly A., Katchur, Steven R., Fivenson, Elayne M., Croteau, Deborah L., Rumsey, William L., Bohr, Vilhelm A.

“…The common oxidatively generated lesion, 8-oxo-7,8-dihydroguanine (8-oxoGua), is removed from DNA by base excision repair. The glycosylase primarily charged…”
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Effects of airborne toxicants on pulmonary function and mitochondrial DNA damage in rodent lungs by Rumsey, William L, Bolognese, Brian, Davis, Alicia B, Flamberg, Pearl L, Foley, Joseph P, Katchur, Steven R, Kotzer, Charles J, Osborn, Ruth R, Podolin, Patricia L

“…Inhalation of airborne toxicants such as cigarette smoke and ozone is a shared health risk among the world's populations. The use of toxic herbicides like…”
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Small Molecule Ogg1 Activators Ameliorate mtDNA Oxidation and Promote Cell Health by Katchur, Steven R, Davis, Alicia M, Ellis, Elizabeth, Pickard, Benjamin, Pyne, Susan, Rumsey, William

“…Abstract only Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation, loss of the alveolar unit, and increased levels…”
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Expression and Purification of Stable 33-kDa Soluble Human CD23 Using the Drosophila S2 Expression System by Khandekar, Sanjay S., Mayer, Ruth J., Cusimano, Donna M., Katchur, Steven R., Appelbaum, Edward R.

“…CD23, a 45-kDa type II membrane glycoprotein present on B cells, monocytes, and other human immune cells, is a low-affinity receptor for IgE. The extracellular…”
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