Search Results - "Katayama, Syouichi"

Straightforward and rapid method for detection of cyclin-dependent kinase-like 5 activity by Katayama, Syouichi, Inazu, Tetsuya

“…Cyclin-dependent kinase-like 5 (CDKL5) is a serine/threonine protein kinase, with its gene mutation leading to a neurodevelopmental disorder. Pathogenic point…”
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Establishment of a Simple Method for Inducing Neuronal Differentiation of P19 EC Cells without Embryoid Body Formation and Analysis of the Role of Histone Deacetylase 8 Activity in This Differentiation by Morii, Atsushi, Katayama, Syouichi, Inazu, Tetsuya

“…P19 pluripotent embryonic carcinoma (EC) stem cells are derived from pluripotent germ cell tumours and can differentiate into three germ layers. Treatment of…”
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Cyclin-Dependent Kinase-Like 5 (CDKL5): Possible Cellular Signalling Targets and Involvement in CDKL5 Deficiency Disorder by Kameshita, Isamu, Inazu, Tetsuya, Sueyoshi, Noriyuki, Katayama, Syouichi

“…Cyclin-dependent kinase-like 5 (CDKL5, also known as STK9) is a serine/threonine protein kinase originally identified in 1998 during a transcriptional mapping…”
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Critical Determinants of Substrate Recognition by Cyclin-Dependent Kinase-like 5 (CDKL5) by Katayama, Syouichi, Sueyoshi, Noriyuki, Kameshita, Isamu

“…Cyclin-dependent kinase-like 5 (CDKL5) is a Ser/Thr protein kinase known to be associated with X-linked neurodevelopmental disorders. In a previous study, we…”
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In Silico Study of Rett Syndrome Treatment-Related Genes, MECP2 , CDKL5 , and FOXG1 , by Evolutionary Classification and Disordered Region Assessment by Fahmi, Muhamad, Yasui, Gen, Seki, Kaito, Katayama, Syouichi, Kaneko-Kawano, Takako, Inazu, Tetsuya, Kubota, Yukihiko, Ito, Masahiro

“…Rett syndrome (RTT), a neurodevelopmental disorder, is mainly caused by mutations in methyl CpG-binding protein 2 ( ), which has multiple functions such as…”
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Subcellular distribution of cyclin-dependent kinase-like 5 (CDKL5) is regulated through phosphorylation by dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) by Oi, Ami, Katayama, Syouichi, Hatano, Naoya, Sugiyama, Yasunori, Kameshita, Isamu, Sueyoshi, Noriyuki

“…Cyclin-dependent kinase-like 5 (CDKL5) is a Ser/Thr protein kinase primarily expressed in the central nervous system and is known to cause X-linked…”
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Yokukansan, a Kampo medicine, enhances the level of neuronal lineage markers in differentiated P19 embryonic carcinoma cells by Fukui, Makoto, Katayama, Syouichi, Ikeya, Yukinobu, Inazu, Tetsuya

“…Yokukansan (YKS), a traditional Japanese Kampo medicine, affects neurological and psychiatric disorders. It ameliorates hippocampal neurogenesis in animals…”
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TandeMBP: generation of a unique protein substrate for protein kinase assays by Kameshita, Isamu, Yamashita, Sho, Katayama, Syouichi, Senga, Yukako, Sueyoshi, Noriyuki

“…Myelin basic protein (MBP) is one of the major components of central nervous system myelin and has multiple sites for protein phosphorylation. Therefore, it…”
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Establishment of a Simple Method for Inducing Neuronal Differentiation of P19 EC Cells without Embryoid Body Formation and Analysis of the Role of Histone Deacetylase 8 Activity in This Differentiation by Atsushi Morii, Syouichi Katayama, Tetsuya Inazu

“…P19 pluripotent embryonic carcinoma (EC) stem cells are derived from pluripotent germ cell tumours and can differentiate into three germ layers. Treatment of…”
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Expression and phosphorylation state analysis of intracellular protein kinases using Multi-PK antibody and Phos-tag SDS-PAGE by Sugiyama, Yasunori, Katayama, Syouichi, Kameshita, Isamu, Morisawa, Keiko, Higuchi, Takuma, Todaka, Hiroshi, Kinoshita, Eiji, Kinoshita-Kikuta, Emiko, Koike, Tohru, Taniguchi, Taketoshi, Sakamoto, Shuji

“…Protein kinase expression and activity play important roles in diverse cellular functions through regulation of phosphorylation signaling. The most commonly…”
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PKL01, an Ndr kinase homologue in plant, shows tyrosine kinase activity by Katayama, S., Sugiyama, Y., Hatano, N., Terachi, T., Sueyoshi, N., Kameshita, I.

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Pro-cathepsin D prevents aberrant protein aggregation dependent on endoplasmic reticulum protein CLN6 by Shiro, Yuki, Katayama, Syouichi, Tsukamoto, Haruka, Yamazaki, Tetsuo

“…We previously expressed a chimeric protein in which the small heat-shock protein αB-crystallin (αBC) is fused at its N-terminus to the C-terminus of the first…”
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HDAC8 regulates neural differentiation through embryoid body formation in P19 cells by Katayama, Syouichi, Morii, Atsushi, Makanga, Juliet O., Suzuki, Takayoshi, Miyata, Naoki, Inazu, Tetsuya

“…Histone acetylation and deacetylation correlate with diverse biological phenomena through gene transcription. Histone deacetylases (HDACs) regulate…”
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Zinc finger protein 483 (ZNF483) regulates neuronal differentiation and methyl-CpG-binding protein 2 (MeCP2) intracellular localization by Yasui, Gen, Katayama, Syouichi, Kubota, Yukihiko, Takatsuka, Hisashi, Ito, Masahiro, Inazu, Tetsuya

“…Rett syndrome (OMIM #312750) is a developmental neurological disorder that is caused by a mutation in methyl-CpG-binding protein 2 (MeCP2). MeCP2 localizes to…”
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Identification of amphiphysin 1 as an endogenous substrate for CDKL5, a protein kinase associated with X-linked neurodevelopmental disorder by Sekiguchi, Mari, Katayama, Syouichi, Hatano, Naoya, Shigeri, Yasushi, Sueyoshi, Noriyuki, Kameshita, Isamu

“…•Mutations in CDKL5 are associated with X-linked neurodevelopmental disorders.•A 120-kDa protein in mouse brain served as an efficient substrate for CDKL5.•An…”
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A novel CDKL5 mutation in a Japanese patient with atypical Rett syndrome by Christianto, Antonius, Katayama, Syouichi, Kameshita, Isamu, Inazu, Tetsuya

“…Rett syndrome (RTT) is a severe X-linked dominant inheritance disorder with a wide spectrum of clinical manifestations. Mutations in Methyl CpG binding protein…”
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High-performance CaMKI: A highly active and stable form of CaMKIδ produced by high-level soluble expression in Escherichia coli by Senga, Yukako, Akizuki, Kazutoshi, Katayama, Syouichi, Shigeri, Yasushi, Kameshita, Isamu, Ishida, Atsuhiko, Sueyoshi, Noriyuki

“…We describe here the expression and characterization of a constitutively active fragment of zebrafish Ca2+/calmodulin-dependent protein kinase (CaMK) Iδ…”
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Expression analyses of splice variants of zebrafish cyclin-dependent kinase-like 5 and its substrate, amphiphysin 1 by Katayama, Syouichi, Senga, Yukako, Oi, Ami, Miki, Yosuke, Sugiyama, Yasunori, Sueyoshi, Noriyuki, Kameshita, Isamu

“…Mammalian cyclin-dependent kinase-like 5 (CDKL5) is a Ser/Thr protein kinase mainly expressed in the central nervous system and believed to be involved in…”
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Characterization of CoPK02, a Ca2+/calmodulin-dependent protein kinase in mushroom Coprinopsis cinerea by Yamashita, Masashi, Sueyoshi, Noriyuki, Yamada, Hiroki, Katayama, Syouichi, Senga, Yukako, Takenaka, Yasuhiro, Ishida, Atsuhiko, Kameshita, Isamu, Shigeri, Yasushi

“…We surveyed genome sequences from the basidiomycetous mushroom Coprinopsis cinerea and isolated a cDNA homologous to CMKA, a calmodulin-dependent protein…”
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Phosphorylated TandeMBP: A unique protein substrate for protein phosphatase assay by Sugiyama, Yasunori, Yamashita, Sho, Uezato, Yuuki, Senga, Yukako, Katayama, Syouichi, Goshima, Naoki, Shigeri, Yasushi, Sueyoshi, Noriyuki, Kameshita, Isamu

“…To analyze a variety of protein phosphatases, we developed phosphorylated TandeMBP (P-TandeMBP), in which two different mouse myelin basic protein isoforms…”
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