Search Results - "Katashima, Masataka"

Pharmacokinetics of Mirabegron, a β3 -Adrenoceptor Agonist for Treatment of Overactive Bladder, in Healthy East Asian Subjects by Iitsuka, Hiromi, MS, van Gelderen, Marcel, PhD, Katashima, Masataka, PhD, Takusagawa, Shin, PhD, Sawamoto, Taiji, PhD

“…Abstract Purpose The objective of these studies was to evaluate the pharmacokinetic profile, safety, and tolerability of mirabegron, a β3 -adrenoceptor agonist…”
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Evaluation of Food and Spherical Carbon Adsorbent Effects on the Pharmacokinetics of Roxadustat in Healthy Nonelderly Adult Male Japanese Subjects by Shibata, Tomohisa, Nomura, Yuki, Takada, Akitsugu, Ueno, Mai, Katashima, Masataka, Yazawa, Rie, Furihata, Kenichi

“…Roxadustat is a hypoxia‐inducible factor prolyl hydroxylase inhibitor in late‐stage clinical development for the treatment of anemia in chronic kidney disease…”
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Pharmacokinetic drug interaction study between overactive bladder drugs mirabegron and tolterodine in Japanese healthy postmenopausal females by Nomura, Yuki, Iitsuka, Hiromi, Toyoshima, Junko, Kuroishi, Kentaro, Hatta, Toshifumi, Kaibara, Atsunori, Katashima, Masataka, Moy, Selina, Sawamoto, Taiji

“…Mirabegron, the first selective β3-adrenoceptor agonist for the treatment of overactive bladder (OAB), inhibits cytochrome P450 isozyme CYP2D6. This study was…”
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Pharmacokinetics and Safety of Amenamevir in Healthy Subjects: Analysis of Four Randomized Phase 1 Studies by Kusawake, Tomohiro, Keirns, James J., Kowalski, Donna, den Adel, Martin, Groenendaal-van de Meent, Dorien, Takada, Akitsugu, Ohtsu, Yoshiaki, Katashima, Masataka

“…Introduction Amenamevir (ASP2151) is a nonnucleoside antiherpesvirus compound available for the treatment of varicella–zoster virus infections. In this article…”
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A phase I, open-label, single-dose micro tracer mass balance study of 14C-labeled ASP7991 in healthy Japanese male subjects using accelerator mass spectrometry by Miyatake, Daisuke, Nakada, Naoyuki, Takada, Akitsugu, Kato, Kota, Taniuchi, Yuta, Katashima, Masataka, Sawamoto, Taiji

“…ASP7991 is a calcimimetic that acts on the calcium-sensing receptor on parathyroid cell membranes and suppresses parathyroid hormone (PTH) secretion in the…”
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A phase I, open-label, single-dose micro tracer mass balance study of 14 C-labeled ASP7991 in healthy Japanese male subjects using accelerator mass spectrometry by Miyatake, Daisuke, Nakada, Naoyuki, Takada, Akitsugu, Kato, Kota, Taniuchi, Yuta, Katashima, Masataka, Sawamoto, Taiji

“…ASP7991 is a calcimimetic that acts on the calcium-sensing receptor on parathyroid cell membranes and suppresses parathyroid hormone (PTH) secretion in the…”
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Integrative pharmacokinetic–pharmacodynamic modeling and simulation of amenamevir (ASP2151) for treatment of recurrent genital herpes by Takada, Akitsugu, Katashima, Masataka, Kaibara, Atsunori, Chono, Koji, Katsumata, Kiyomitsu, Sawamoto, Taiji, Suzuki, Hiroshi, Yano, Yoshitaka

“…Amenamevir is a novel drug that targets the viral helicase–primase complex. While dose-dependent efficacy had been observed in non-clinical studies, no clear…”
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The Influence of Hepatic and Renal Impairment on the Pharmacokinetics of a Treatment for Herpes Zoster, Amenamevir (ASP2151): Phase 1, Open-Label, Single-Dose, Parallel-Group Studies by Kusawake, Tomohiro, Kowalski, Donna, Takada, Akitsugu, Kato, Kota, Katashima, Masataka, Keirns, James J., Lewand, Michaelene, Lasseter, Kenneth C., Marbury, Thomas C., Preston, Richard A.

“…Introduction Amenamevir (ASP2151) is a nonnucleoside human herpesvirus helicase-primase inhibitor that was approved in Japan for the treatment of herpes zoster…”
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Linear Pharmacokinetics of Micafungin and Its Active Metabolites in Japanese Pediatric Patients with Fungal Infections by Tabata, Kenji, Katashima, Masataka, Kawamura, Akio, Tanigawara, Yusuke, Sunagawa, Keisuke

“…The objective of this study was to propose the appropriate dosage regimen of micafungin for pediatric use, considering the effects of dose-linearity, age and…”
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Role of micafungin in the antifungal armamentarium by Ikeda, Fumiaki, Tanaka, Shigeki, Ohki, Hidenori, Matsumoto, Satoru, Maki, Katsuyuki, Katashima, Masataka, Barrett, David, Aoki, Yoshiyasu

“…Serious infections caused by opportunistic molds remain a major problem for public health. Immune deficiency following organ transplantation and aggressive…”
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Japanese bioanalytical method validation guideline: the world's first regulatory guideline dedicated to ligand-binding assays by Imazato-Hirano, Mami, Taniguchi, Yoshitaka, Kakehi, Masaaki, Kuze, Yoji, Nakamura, Takahiro, Minamide, Yoshiyuki, Miya, Kazuhiro, Hosogi, Jun, Katashima, Masataka, Maekawa, Kotaro, Okuda, Haruhiro, Niimi, Shingo, Kawasaki, Nana, Ishii-Watabe, Akiko, Katori, Noriko

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Pharmacological and clinical profile of nitisinone (Orfadin(®) Capsules): a therapeutic agent for hereditary tyrosinemia type 1 by Minoura, Hideaki, Iwai, Megumi, Taniuchi, Yuta, Katashima, Masataka, Takahashi, Hideyuki

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Population Pharmacokinetic Analysis of Micafungin in Japanese Patients with Fungal Infections by Tabata, Kenji, Katashima, Masataka, Kawamura, Akio, Kaibara, Atsunori, Tanigawara, Yusuke

“…The object of this analysis was to develop a population pharmacokinetic model of micafungin, a new anti-fungal agent of the echinocandin class, to optimize…”
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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP3652, a Reversible Fatty Acid Amide Hydrolase Inhibitor, in Healthy, Nonelderly, Japanese Men and Elderly, Japanese Men and Women: A Randomized, Double-blind, Placebo-controlled, Single and Multiple Oral Dose, Phase I Study by Takizawa, Masaomi, Hatta, Toshifumi, Iitsuka, Hiromi, Katashima, Masataka, Sato, Yuichiro, Kuroishi, Kentaro, Nagashima, Hirotaka

“…This study aimed to evaluate the safety, tolerability, and pharmacokinetic and pharmacodynamic properties of ASP3652, a peripherally acting inhibitor of…”
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Population Pharmacokinetics Analysis of Quetiapine Extended-release Formulation in Japanese Patients with Bipolar Depression by Fukushi, Risa, Nomura, Yuki, Katashima, Masataka, Komatsu, Kanji, Sato, Yuichiro, Takada, Akitsugu

“…The objectives of this study were to explore covariates of plasma quetiapine concentrations after oral administration of quetiapine extended-release…”
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Approach to Evaluating QT Prolongation of Quetiapine Fumarate in Late Stage of Clinical Development Using Concentration-QTc Modeling and Simulation in Japanese Patients With Bipolar Disorder by Fukushi, Risa, Nomura, Yuki, Katashima, Masataka, Komatsu, Kanji, Sato, Yuichiro, Takada, Akitsugu

“…Quetiapine has been reported to prolong the QT interval, and has been used as a positive control in thorough QT studies. The objective of the present study was…”
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Comparison of Pharmacokinetic Profiles of Beraprost Sustained Release in Japanese, Chinese, and Korean Healthy Adult Males by Nakajo, Ikumi, Inoue, Hiroshi, Inaba, Masaki, Oikawa, Keishi, Katashima, Masataka, Sawamoto, Taiji, Kurumatani, Hajimu, Shiramoto, Masanari

“…Background and Objectives Beraprost sodium (BPS), an orally administrable prostaglandin I 2 derivative, is used for the treatment of chronic arterial occlusion…”
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Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects with Normal and Impaired Renal Function by Miyatake, Daisuke, Shibata, Tomohisa, Shibata, Mai, Kaneko, Yuichiro, Oda, Kazuo, Nishimura, Tetsuya, Katashima, Masataka, Sekino, Hisakuni, Furihata, Kenichi, Urae, Akinori

“…Background and Objective This study measured and compared the exposure and safety of peficitinib (ASP015K), a novel oral Janus kinase inhibitor, in subjects…”
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Analytical method validation for biomarkers as a drug development tool: points to consider by Ohtsu, Yoshiaki, Tanaka, Seiji, Igarashi, Harue, Kakehi, Masaaki, Mori, Tamiki, Nakamura, Takahiro, Ohashi, Rui, Shimizu, Hiroyuki, Yasuda, Yutaka, Okayama, Takashige, Kakuo, Hiroyuki, Yokoi, Hiroyuki, Horiuchi, Mizuki, Katashima, Masataka, Nakamura, Ryosuke, Saito, Kosuke, Saito, Yoshiro

“…Biomarkers are an important drug developmental tool. Assessment of quantitative analytical methods of biomarkers is not included in any regulatory documents in…”
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Linear Pharmacokinetics of Micafungin and Its Active Metabolites in Japanese Pediatric Patients with Fungal Infections by Kenji TABATAa, Masataka KATASHIMAb, Akio KAWAMURAc, Yusuke TANIGAWARAd, Keisuke SUNAGAWAe

“…The objective of this study was to propose the appropriate dosage regimen of micafungin for pediatric use, considering the effects of dose-linearity, age and…”
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