Search Results - "Kataru, Raghu"

Inflammatory Manifestations of Lymphedema by Ly, Catherine L, Kataru, Raghu P, Mehrara, Babak J

“…Lymphedema results from lymphatic insufficiency leading to a progressive inflammatory process that ultimately manifests as discomfort, recurrent infections,…”
Get full text

Inflammation-associated lymphangiogenesis: a double-edged sword? by Kim, Honsoul, Kataru, Raghu P, Koh, Gou Young

“…Lymphangiogenesis and lymphatic vessel remodeling are complex biological processes frequently observed during inflammation. Accumulating evidence indicates…”
Get full text

Lymphedema: Pathogenesis and Novel Therapies by Dayan, Joseph H, Ly, Catherine L, Kataru, Raghu P, Mehrara, Babak J

“…Lymphedema affects up to 1 in 6 patients who undergo treatment for a solid tumor in the United States. Its prevalence has increased as more effective oncologic…”
Get full text

Stem cell-driven lymphatic remodeling coordinates tissue regeneration by Gur-Cohen, Shiri, Yang, Hanseul, Baksh, Sanjeethan C, Miao, Yuxuan, Levorse, John, Kataru, Raghu P, Liu, Xiaolei, de la Cruz-Racelis, June, Mehrara, Babak J, Fuchs, Elaine

“…Tissues rely on stem cells (SCs) for homeostasis and wound repair. SCs reside in specialized microenvironments (niches) whose complexities and roles in…”
Get full text

Histopathologic Features of Lymphedema: A Molecular Review by Li, Claire Y, Kataru, Raghu P, Mehrara, Babak J

“…An estimated 5 million people in the United States are affected by secondary lymphedema, with most cases attributed to malignancies or malignancy-related…”
Get full text

The Vicious Circle of Stasis, Inflammation, and Fibrosis in Lymphedema by Brown, Stav, Dayan, Joseph H., Kataru, Raghu P., Mehrara, Babak J.

“…Lymphedema is a progressive disease of the lymphatic system arising from impaired lymphatic drainage, accumulation of interstitial fluid, and fibroadipose…”
Get full text

Skin microbiome alterations in upper extremity secondary lymphedema by Campbell, Adana-Christine, Fei, Teng, Baik, Jung Eun, Park, Hyeung Ju, Shin, Jinyeon, Kuonqui, Kevin, Brown, Stav, Sarker, Ananta, Kataru, Raghu P, Mehrara, Babak J

“…Lymphedema is a chronic condition that commonly occur from lymphatic injury following surgical resection of solid malignancies. While many studies have…”
Get full text

Regulation and implications of inflammatory lymphangiogenesis by Kim, Honsoul, Kataru, Raghu P, Koh, Gou Young

“…Lymphatic vessels (LVs) are highly dynamic structures that intimately interact with their surrounding microenvironment. They have a profound influence on the…”
Get full text

Th2 cytokines inhibit lymphangiogenesis by Savetsky, Ira L, Ghanta, Swapna, Gardenier, Jason C, Torrisi, Jeremy S, García Nores, Gabriela D, Hespe, Geoffrey E, Nitti, Matthew D, Kataru, Raghu P, Mehrara, Babak J

“…Lymphangiogenesis is the process by which new lymphatic vessels grow in response to pathologic stimuli such as wound healing, inflammation, and tumor…”
Get full text

Lymphatics act as a signaling hub to regulate intestinal stem cell activity by Niec, Rachel E., Chu, Tinyi, Schernthanner, Marina, Gur-Cohen, Shiri, Hidalgo, Lynette, Pasolli, Hilda Amalia, Luckett, Kathleen A., Wang, Zhong, Bhalla, Sohni R., Cambuli, Francesco, Kataru, Raghu P., Ganesh, Karuna, Mehrara, Babak J., Pe’er, Dana, Fuchs, Elaine

“…Barrier epithelia depend upon resident stem cells for homeostasis, defense, and repair. Epithelial stem cells of small and large intestines (ISCs) respond to…”
Get full text

Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution by Kataru, Raghu P., Jung, Keehoon, Jang, Cholsoon, Yang, Hanseul, Schwendener, Reto A., Baik, Jung Eun, Han, Seung Hyun, Alitalo, Kari, Koh, Gou Young

“…Using a bacterial pathogen–induced acute inflammation model in the skin, we defined the roles of local lymphatic vessels and draining lymph nodes (DLNs) in…”
Get full text

Topical tacrolimus for the treatment of secondary lymphedema by Gardenier, Jason C., Kataru, Raghu P., Hespe, Geoffrey E., Savetsky, Ira L., Torrisi, Jeremy S., Nores, Gabriela D. García, Jowhar, Dawit K., Nitti, Matthew D., Schofield, Ryan C., Carlow, Dean C., Mehrara, Babak J.

“…Secondary lymphedema, a life-long complication of cancer treatment, currently has no cure. Lymphedema patients have decreased quality of life and recurrent…”
Get full text

Regulation of Lymphatic Function in Obesity by Kataru, Raghu P., Park, Hyeong Ju, Baik, Jung Eun, Li, Claire, Shin, Jinyeon, Mehrara, Babak J.

“…The lymphatic system has many functions, including macromolecules transport, fat absorption, regulation and modulation of adaptive immune responses, clearance…”
Get full text

Fibrosis and secondary lymphedema: chicken or egg? by Kataru, Raghu P., Wiser, Itay, Baik, Jung Eun, Park, Hyeung Ju, Rehal, Sonia, Shin, Jin Yeon, Mehrara, Babak J.

“…Secondary lymphedema is a common complication of cancer treatment resulting in progressive fibroadipose tissue deposition, increased risk of infections, and,…”
Get full text

Regulation of Immune Function by the Lymphatic System in Lymphedema by Kataru, Raghu P, Baik, Jung Eun, Park, Hyeung Ju, Wiser, Itay, Rehal, Sonia, Shin, Jin Yeon, Mehrara, Babak J

“…The lymphatic vasculature has traditionally been thought to play a passive role in the regulation of immune responses by transporting antigen presenting cells…”
Get full text

CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema by García Nores, Gabriela D., Ly, Catherine L., Cuzzone, Daniel A., Kataru, Raghu P., Hespe, Geoffrey E., Torrisi, Jeremy S., Huang, Jung Ju, Gardenier, Jason C., Savetsky, Ira L., Nitti, Matthew D., Yu, Jessie Z., Rehal, Sonia, Mehrara, Babak J.

“…T cell-mediated responses have been implicated in the development of fibrosis, impaired lymphangiogenesis, and lymphatic dysfunction in secondary lymphedema…”
Get full text

Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function by Kataru, Raghu P, Baik, Jung Eun, Park, Hyeung Ju, Ly, Catherine L, Shin, Jinyeon, Schwartz, Noa, Lu, Theresa T, Ortega, Sagrario, Mehrara, Babak J

“…Exogenous administration of lymphangiogenic growth factors is widely used to study changes in lymphatic function in pathophysiology. However, this approach can…”
Get more information

Lymphatics in Tumor Progression and Immunomodulation by Li, Claire Y, Brown, Stav, Mehrara, Babak J, Kataru, Raghu P

“…The lymphatic system consists of a unidirectional hierarchy of vessels responsible for fluid homeostasis, lipid absorption, and the transport of immune cells…”
Get full text

Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema by Szőke, Dániel, Kovács, Gábor, Kemecsei, Éva, Bálint, László, Szoták-Ajtay, Kitti, Aradi, Petra, Styevkóné Dinnyés, Andrea, Mui, Barbara L., Tam, Ying K., Madden, Thomas D., Karikó, Katalin, Kataru, Raghu P., Hope, Michael J., Weissman, Drew, Mehrara, Babak J., Pardi, Norbert, Jakus, Zoltán

“…Lack or dysfunction of the lymphatics leads to secondary lymphedema formation that seriously reduces the function of the affected organs and results in…”
Get full text

Lymph Node Transplantation Decreases Swelling and Restores Immune Responses in a Transgenic Model of Lymphedema by Huang, Jung-Ju, Gardenier, Jason C, Hespe, Geoffrey E, García Nores, Gabriela D, Kataru, Raghu P, Ly, Catherine L, Martínez-Corral, Inés, Ortega, Sagrario, Mehrara, Babak J

“…Secondary lymphedema is a common complication of cancer treatment and recent studies have demonstrated that lymph node transplantation (LNT) can decrease…”
Get full text