Search Results - "Katare, Parmeshwar B."
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SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM
Published in Cells (Basel, Switzerland) (28-11-2018)“…Mitochondrial dysfunction remains the crucial cause for many heart diseases including diabetic cardiomyopathy (DCM). Sirtuin-3 (SIRT-3) is a protein…”
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Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats
Published in Frontiers in immunology (22-06-2017)“…Inflammation remains a crucial factor for progression of cardiac diseases and cardiac hypertrophy remains an important cause of cardiac failure over all age…”
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Repositioning of Drugs in Cardiometabolic Disorders: Importance and Current Scenario
Published in Current topics in medicinal chemistry (01-08-2016)“…Cardiometabolic disorder (CMD) is a cluster of diseases, including cardiovascular diseases (CVDs), metabolic syndrome (MS) and diabetes mellitus (DM)…”
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Energy metabolism in skeletal muscle cells from donors with different body mass index
Published in Frontiers in physiology (17-11-2022)“…Obesity and physical inactivity have a profound impact on skeletal muscle metabolism. In the present work, we have investigated differences in protein…”
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Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia
Published in Journal of the American Heart Association (18-02-2020)“…Background Hyperhomocysteinemia is a risk factor for ischemic stroke; however, a targeted treatment strategy is lacking partly because of limited understanding…”
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Krill oil supplementation in vivo promotes increased fuel metabolism and protein synthesis in cultured human skeletal muscle cells
Published in Frontiers in nutrition (Lausanne) (28-10-2024)“…Introduction Krill oil is a dietary supplement derived from Antarctic krill; a small crustacean found in the ocean. Krill oil is a rich source of omega-3 fatty…”
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Thrombotic potential during pediatric acute lymphoblastic leukemia induction: Role of cell‐free DNA
Published in Research and practice in thrombosis and haemostasis (01-07-2021)“…Thromboembolism affects up to 30% of children undergoing treatment for acute lymphoblastic leukemia (ALL). Increased thrombin generation has been reported in…”
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Exploring the potential of novel pH sensitive lipoplexes for tumor targeted gene delivery with reduced toxicity
Published in International journal of pharmaceutics (05-01-2020)“…[Display omitted] The present investigation explores the potential of pH sensitive cationic liposomes for its in vivo tumor targeted gene transfection in…”
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ε-Poly-l-Lysine/plasmid DNA nanoplexes for efficient gene delivery in vivo
Published in International journal of pharmaceutics (05-05-2018)“…[Display omitted] The present work addresses the development and characterization of ε-Poly-l-Lysine/pDNA polyplexes and evaluation for their improved…”
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Green surfactant-dendrimer aggreplexes: An ingenious way to launch dual attack on arch-enemy cancer
Published in Colloids and surfaces, B, Biointerfaces (01-08-2021)“…[Display omitted] •Aggreplexes are complexes between green-surfactant-dendrimer aggregates and shRNA.•Aggreplexes showed ∼1.87-fold higher cell uptake…”
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Musa balbisiana Fruit Rich in Polyphenols Attenuates Isoproterenol-Induced Cardiac Hypertrophy in Rats via Inhibition of Inflammation and Oxidative Stress
Published in Oxidative medicine and cellular longevity (2020)“…Musa balbisiana Colla (Family: Musaceae), commonly known as banana and native to India and other parts of Asia, is very rich in nutritional value and has…”
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Paricalcitol Attenuates Metabolic Syndrome-Associated Heart Failure through Enhanced Mitochondrial Fusion
Published in Oxidative medicine and cellular longevity (11-06-2022)“…Objectives. Transition from cardiac hypertrophy to failure involves adverse metabolic reprogramming involving mitochondrial dysfunction. We have earlier shown…”
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pH sensitive liposomes assisted specific and improved breast cancer therapy using co-delivery of SIRT1 shRNA and Docetaxel
Published in Materials Science & Engineering C (01-01-2021)“…Combining the bio-therapeutics with chemotherapeutic drugs can assist in augmenting the therapeutic standards by increasing the efficacy and decreasing the…”
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