Search Results - "Katafuchi, Atsushi"

Homologous Recombination but Not Nucleotide Excision Repair Plays a Pivotal Role in Tolerance of DNA-Protein Cross-links in Mammalian Cells by Nakano, Toshiaki, Katafuchi, Atsushi, Matsubara, Mayumi, Terato, Hiroaki, Tsuboi, Tomohiro, Masuda, Tasuku, Tatsumoto, Takahiro, Pack, Seung Pil, Makino, Keisuke, Croteau, Deborah L., Van Houten, Bennett, Iijima, Kenta, Tauchi, Hiroshi, Ide, Hiroshi

“…DNA-protein cross-links (DPCs) are unique among DNA lesions in their unusually bulky nature. The steric hindrance imposed by cross-linked proteins (CLPs) will…”
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Increase in dicentric chromosome formation after a single CT scan in adults by Abe, Yu, Miura, Tomisato, Yoshida, Mitsuaki A., Ujiie, Risa, Kurosu, Yumiko, Kato, Nagisa, Katafuchi, Atsushi, Tsuyama, Naohiro, Ohba, Takashi, Inamasu, Tomoko, Shishido, Fumio, Noji, Hideyoshi, Ogawa, Kazuei, Yokouchi, Hiroshi, Kanazawa, Kenya, Ishida, Takashi, Muto, Satoshi, Ohsugi, Jun, Suzuki, Hiroyuki, Ishikawa, Tetsuo, Kamiya, Kenji, Sakai, Akira

“…Excess risk of leukemia and brain tumors after CT scans in children has been reported. We performed dicentric chromosome assay (DCAs) before and after CT scan…”
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Analysis of chromosome translocation frequency after a single CT scan in adults by Abe, Yu, Miura, Tomisato, Yoshida, Mitsuaki A., Ujiie, Risa, Kurosu, Yumiko, Kato, Nagisa, Katafuchi, Atsushi, Tsuyama, Naohiro, Kawamura, Fumihiko, Ohba, Takashi, Inamasu, Tomoko, Shishido, Fumio, Noji, Hideyoshi, Ogawa, Kazuei, Yokouchi, Hiroshi, Kanazawa, Kenya, Ishida, Takashi, Muto, Satoshi, Ohsugi, Jun, Suzuki, Hiroyuki, Ishikawa, Tetsuo, Kamiya, Kenji, Sakai, Akira

“…We recently reported an increase in dicentric chromosome (DIC) formation after a single computed tomography (CT) scan (5.78–60.27 mSv: mean 24.24 mSv) and we…”
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Identification of low-dose responsive metabolites in X-irradiated human B lymphoblastoid cells and fibroblasts by Tsuyama, Naohiro, Mizuno, Hajime, Katafuchi, Atsushi, Abe, Yu, Kurosu, Yumiko, Yoshida, Mitsuaki, Kamiya, Kenji, Sakai, Akira

“…Ionizing radiation (IR) induces cellular stress responses, such as signal transduction, gene expression, protein modification, and metabolite change that…”
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Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells by Kawamura, Fumihiko, Inaki, Makoto, Katafuchi, Atsushi, Abe, Yu, Tsuyama, Naohiro, Kurosu, Yumiko, Yanagi, Aki, Higuchi, Mitsunori, Muto, Satoshi, Yamaura, Takumi, Suzuki, Hiroyuki, Noji, Hideyoshi, Suzuki, Shinichi, Yoshida, Mitsuaki A., Sasatani, Megumi, Kamiya, Kenji, Onodera, Masafumi, Sakai, Akira

“…B cell derived induced pluripotent stem cells (BiPSCs) were recently established from peripheral blood B cells by the simultaneous transfection of Yamanaka…”
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Differential Specificity of Human and Escherichia coli Endonuclease III and VIII Homologues for Oxidative Base Lesions by Katafuchi, Atsushi, Nakano, Toshiaki, Masaoka, Aya, Terato, Hiroaki, Iwai, Shigenori, Hanaoka, Fumio, Ide, Hiroshi

“…In human cells, oxidative pyrimidine lesions are restored by the base excision repair pathway initiated by homologues of Endo III (hNTH1) and Endo VIII (hNEIL1…”
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Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[ a]pyrene-guanine adducts by human DNA polymerase kappa by Sassa, Akira, Niimi, Naoko, Fujimoto, Hirofumi, Katafuchi, Atsushi, Grúz, Petr, Yasui, Manabu, Gupta, Ramesh C., Johnson, Francis, Ohta, Toshihiro, Nohmi, Takehiko

“…[Display omitted] ▶ Phenylalanine 171 is inhibitory for translesion bypass by human DNA polymerase kappa. ▶ The change of the amino acid to alanine enhanced…”
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1C-01 Relationship between special characteristics of DNA polymerase III in Escherichia coli and high spontaneous mutations of mutT mutator strain by YAMADA Masami, SHIMIZU Masatomi, KATAFUCHI Atsushi, GRUZ Petr, Fujii Shingo, USUI Yukio, FUCHS Robert P, NOHMI Takehiko

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DNA polymerases involved in the incorporation of oxidized nucleotides into DNA: Their efficiency and template base preference by Katafuchi, Atsushi, Nohmi, Takehiko

“…Genetic information must be duplicated with precision and accurately passed on to daughter cells and later generations. In order to achieve this goal, DNA…”
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3E-02 Involvement of DNA polymerase III in A-to-C induced transversions via mis-incorporation of 8-oxo-dGTP in Escherichia coli by YAMADA Masami, SHIMIZU Masatomi, KATAFUCHI Atsushi, FUJII Shingo, USUI Yukio, FUCHS Robert P, NOHMI Takehiko

“…Reactive oxygen species induce oxidative damage in DNA as well as in the precursors, i.e., dNTPs, and incorporation of oxidized dNTPs into DNA is regarded as a…”
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DNA polymerases involved in the incorporation of oxidized nucleotides into DNA: Their efficiency and template base preference: Nucleotide Pool Damage and Its Biological Consequences by KATAFUCHI, Atsushi, NOHMI, Takehiko

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Induction of t(11;14) IgH enhancer/promoter- cyclin D1 gene translocation using CRISPR/Cas9 by Tsuyama, Naohiro, Abe, Yu, Yanagi, Aki, Yanai, Yukari, Sugai, Misaki, Katafuchi, Atsushi, Kawamura, Fumihiko, Kamiya, Kenji, Sakai, Akira

“…Chromosomal translocation is a key process in the oncogenic transformation of somatic cells. Previously, artificial induction of chromosomal translocation was…”
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Nucleotide Excision Repair and Homologous Recombination Systems Commit Differentially to the Repair of DNA-Protein Crosslinks by Nakano, Toshiaki, Morishita, Soh, Katafuchi, Atsushi, Matsubara, Mayumi, Horikawa, Yusuke, Terato, Hiroaki, Salem, Amir M.H., Izumi, Shunsuke, Pack, Seung Pil, Makino, Keisuke, Ide, Hiroshi

“…DNA-protein crosslinks (DPCs)—where proteins are covalently trapped on the DNA strand—block the progression of replication and transcription machineries and…”
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B Cell-Derived Induced Pluripotent Stem Cells Are Useful for Determining the Cellular Origin of Abnormal B Cells in Multiple Myeloma by Yanagi, Aki, Kawamura, Fumihiko, Inaki, Makoto, Katafuchi, Atsushi, Yanai, Yukari, Abe, Yu, Tsuyama, Naohiro, Sugai, Misaki, Higuchi, Mitsunori, Muto, Satoshi, Yamaura, Takumi, Suzuki, Hiroyuki, Noji, Hideyoshi, Suzuki, Shinichi, Mitsuaki, Yoshida A, Sasatani, Megumi, Kamiya, Kenji, Onodera, Masafumi, Sakai, Akira

“…Induced pluripotent stem cells (iPSCs) are generated by the genetic reprogramming of somatic cells. In addition to regenerative medicine, these cells have been…”
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Escherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains by Yamada, Masami, Shimizu, Masatomi, Katafuchi, Atsushi, Grúz, Petr, Fujii, Shingo, Usui, Yukio, Fuchs, Robert P., Nohmi, Takehiko

“…Summary Reactive oxygen species induce oxidative damage in DNA precursors, i.e. dNTPs, leading to point mutations upon incorporation. Escherichia coli mutT…”
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Establishment of Induced Pluripotent Stem Cells from Lymph Node B Cells and Induction of Aid Expression in Their Differentiation into Hematopoietic Stem Cells by Kawamura, Fumihiko, Makoto, Inaki, Katafuchi, Atsushi, Abe, Yu, Tsuyama, Naohiro, Kurosu, Yumiko, Yanagi, Aki, Higuchi, Mitsunori, Muto, Satoshi, Yamamura, Takumi, Suzuki, Hiroyuki, Noji, Hideyoshi, Suzuki, Shinichi, Yoshida, Mitsuaki A, Sasatani, Megumi, Kamiya, Kenji, Onodera, Masafumi, Sakai, Akira

“…Induced pluripotent stem cells (iPSCs) have been established from a variety of somatic cells not only for regenerative medicine but also for studies of the…”
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Critical amino acids in human DNA polymerases η and κ involved in erroneous incorporation of oxidized nucleotides by Katafuchi, Atsushi, Sassa, Akira, Niimi, Naoko, Grúz, Petr, Fujimoto, Hirofumi, Masutani, Chikahide, Hanaoka, Fumio, Ohta, Toshihiro, Nohmi, Takehiko

“…Oxidized DNA precursors can cause mutagenesis and carcinogenesis when they are incorporated into the genome. Some human Y-family DNA polymerases (Pols) can…”
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The Steric Gate Amino Acid Tyrosine 112 Is Required for Efficient Mismatched-Primer Extension by Human DNA Polymerase κ by Niimi, Naoko, Sassa, Akira, Katafuchi, Atsushi, Grúz, Petr, Fujimoto, Hirofumi, Bonala, Radha-Rani, Johnson, Francis, Ohta, Toshihiro, Nohmi, Takehiko

“…Human DNA is continuously damaged by exogenous and endogenous genotoxic insults. To counteract DNA damage and ensure the completion of DNA replication, cells…”
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E scherichia coli DNA polymerase III is responsible for the high level of spontaneous mutations in mutT strains by Yamada, Masami, Shimizu, Masatomi, Katafuchi, Atsushi, Grúz, Petr, Fujii, Shingo, Usui, Yukio, Fuchs, Robert P., Nohmi, Takehiko

“…Reactive oxygen species induce oxidative damage in DNA precursors, i.e. dNTPs , leading to point mutations upon incorporation. E scherichia coli mutT strains,…”
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In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ by Sassa, Akira, Suzuki, Tetsuya, Kanemaru, Yuki, Niimi, Naoko, Fujimoto, Hirofumi, Katafuchi, Atsushi, Grúz, Petr, Yasui, Manabu, Gupta, Ramesh C., Johnson, Francis, Ohta, Toshihiro, Honma, Masamitsu, Adachi, Noritaka, Nohmi, Takehiko

“…•Human cell lines that express a variant form of Pol κ (F171A) were established.•The cells exhibited lower mutation frequency toward benzo[a]pyrene DNA…”
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