Search Results - "Kasza, K E"

Filamin A Is Essential for Active Cell Stiffening but not Passive Stiffening under External Force by Kasza, K.E., Nakamura, F., Hu, S., Kollmannsberger, P., Bonakdar, N., Fabry, B., Stossel, T.P., Wang, N., Weitz, D.A.

“…The material properties of a cell determine how mechanical forces are transmitted through and sensed by that cell. Some types of cells stiffen passively under…”
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Actin Filament Length Tunes Elasticity of Flexibly Cross-Linked Actin Networks by Kasza, K.E., Broedersz, C.P., Koenderink, G.H., Lin, Y.C., Messner, W., Millman, E.A., Nakamura, F., Stossel, T.P., MacKintosh, F.C., Weitz, D.A.

“…Networks of the cytoskeletal biopolymer actin cross-linked by the compliant protein filamin form soft gels that stiffen dramatically under shear stress. We…”
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Glioma Expansion in Collagen I Matrices: Analyzing Collagen Concentration-Dependent Growth and Motility Patterns by Kaufman, L.J., Brangwynne, C.P., Kasza, K.E., Filippidi, E., Gordon, V.D., Deisboeck, T.S., Weitz, D.A.

“…We study the growth and invasion of glioblastoma multiforme (GBM) in three-dimensional collagen I matrices of varying collagen concentration. Phase-contrast…”
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Ice slurry applications by Kauffeld, M., Wang, M.J., Goldstein, V., Kasza, K.E.

“…The role of secondary refrigerants is expected to grow as the focus on the reduction of greenhouse gas emissions increases. The effectiveness of secondary…”
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Comparative genomics analysis of human sequence variation in the UGT1A gene cluster by Maitland, M L, Grimsley, C, Kuttab-Boulos, H, Witonsky, D, Kasza, K E, Yang, L, Roe, B A, Di Rienzo, A

“…Common polymorphisms within the human UGT1A gene locus are associated with irinotecan and tranilast toxicity. To uncover additional functional variation across…”
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Visualizing the strain field in semiflexible polymer networks: strain fluctuations and nonlinear rheology of F-actin gels by Liu, J, Koenderink, G H, Kasza, K E, Mackintosh, F C, Weitz, D A

“…We image semiflexible polymer networks under shear at the micrometer scale. By tracking embedded probe particles, we determine the local strain field, and…”
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Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior by Wakschlag, L S, Kistner, E O, Pine, D S, Biesecker, G, Pickett, K E, Skol, A D, Dukic, V, Blair, R J R, Leventhal, B L, Cox, N J, Burns, J L, Kasza, K E, Wright, R J, Cook, E H

“…Genetic susceptibility to antisocial behavior may increase fetal sensitivity to prenatal exposure to cigarette smoke. Testing putative gene × exposure…”
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Nonlinear elasticity of stiff biopolymers connected by flexible linkers by Kasza, K E, Koenderink, G H, Lin, Y C, Broedersz, C P, Messner, W, Nakamura, F, Stossel, T P, MacKintosh, F C, Weitz, D A

“…Networks of the biopolymer actin, cross-linked by the compliant protein filamin, form soft gels. They can, however, withstand large shear stresses due to their…”
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Ice slurry applications: Phase Change Materials and Slurries for Refrigeration and Air Conditioning by KAUFFELD, M, WANG, M. J, GOLDSTEIN, V, KASZA, K. E

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Evaluation of precipitates used in strainer head loss testing: Part II. Precipitates by in situ aluminum alloy corrosion by Bahn, Chi Bum, Kasza, Ken E., Shack, William J., Natesan, Ken, Klein, Paul

“…[Display omitted] ► Sump strainer head loss testing to evaluate chemical effects. ► Aluminum hydroxide precipitates by in situ Al alloy corrosion caused head…”
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Evaluation of precipitates used in strainer head loss testing: Part III. Long-term aluminum hydroxide precipitation tests in borated water by Bahn, Chi Bum, Kasza, Ken E., Shack, William J., Natesan, Ken, Klein, Paul

“…▶ Aluminum hydroxide precipitation boundary is similar to that for amorphous phase. ▶ Various precipitation tests are combined into one map in temperature-‘pH…”
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Evaluation of precipitates used in strainer head loss testing. Part I. Chemically generated precipitates by Bahn, Chi Bum, Kasza, Ken E., Shack, William J., Natesan, Ken, Klein, Paul

“…The purpose of the current program was to evaluate the properties of chemical precipitates proposed by industry that have been used in sump strainer head loss…”
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Effects of vascular endothelial growth factor (VEGF) signaling inhibition on human erythropoiesis by Maitland, M. L., Kasza, K. E., Snider, K. L., Sit, L., Cohen, E. E., Seiwert, T. Y., Karrison, T., Ratain, M. J., Vokes, E. E.

“…Abstract only 3575 Background: In rodents, inhibition of VEGF signaling increases production of red blood cells. Major clinical trials of VEGF signaling…”
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Refining epidermal growth factor receptor (EGFR) -inhibition-related rash (EIRR) phenotypes with a cetuximab (C) monotherapy stage of a phase II trial for non-small cell lung cancer (NSCLC) by Maitland, M. L., Kasza, K. E., Lacouture, M. E., Liu, W., Soltani, K., Kozloff, M. F., Hoffman, P. C., Salgia, R., Karrison, T., Vokes, E. E.

“…Abstract only…”
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Activity of sorafenib (SOR) in patients (pts) with imatinib (IM) and sunitinib (SU)-resistant (RES) gastrointestinal stromal tumors (GIST): A phase II trial of the University of Chicago Phase II Consortium by Wiebe, L., Kasza, K. E., Maki, R. G., D’Adamo, D. R., Chow, W. A., Wade III, J. L., Agamah, E., Stadler, W. M., Vokes, E. E., Kindler, H. L.

“…Abstract only…”
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Is Prenatal Smoking Associated with a Developmental Pattern of Conduct Problems in Young Boys? by Wakschlag, Lauren S, Pickett, Kate E, Kasza, Kristen E, Loeber, Rolf

“…Objective: Prenatal smoking is robustly associated with increased risk of conduct problems in offspring. Observational studies that provide detailed phenotypic…”
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Blood pressure (BP) as a biomarker for sorafenib (S), an inhibitor of the vascular endothelial growth factor (VEGF) signaling pathway by Maitland, M. L., Moshier, K., Imperial, J., Kasza, K. E., Karrison, T., Elliott, W., Undevia, S. D., Stadler, W., Desai, A. A., Ratain, M. J.

“…Abstract only 2035 Background: Hypertension is a commonly reported toxicity of agents that inhibit the VEGF signaling pathway (VSP). This new class of cancer…”
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Leak behavior of SCC degraded steam generator tubings of nuclear power plant by Hwang, Seong Sik, Kim, Hong Pyo, Kim, Joung Soo, Kasza, Kenneth E., Park, Jangyul, Shack, William J.

“…A forced outage due to a steam generator tube leak in a Korean nuclear power plant has been reported [Kim, J.S., Hwang, S.S., et al., 1999. KAERI Internal…”
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Phase behavior and rheology of sticky rod-like particles by Huang, F, Rotstein, R, Kasza, K. E, Flynn, N. T, Fraden, S

“…We construct colloidal ``sticky'' rods from the semi-flexible filamentous fd virus and temperature-sensitive polymers poly(N-isopropylacrylamide) (PNIPAM). The…”
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Visualizing the strain field in semiflexible polymer networks: strain fluctuations and nonlinear rheology of F-actin gels by Liu, J, Koenderink, G. H, Kasza, K. E, MacKintosh, F. C, Weitz, D. A

“…We image semi-flexible polymer networks under shear at the micrometer scale. By tracking embedded probe particles, we determine the local strain field, and…”
Get full text