Search Results - "Kastrup, Jens"

Short- and Long-Term Cause of Death in Patients Treated With Primary PCI for STEMI by Pedersen, Frants, MD, PhD, Butrymovich, Vitalij, MD, Kelbæk, Henning, MD, DMSc, Wachtell, Kristian, MD, PhD, Helqvist, Steffen, MD, DMSc, Kastrup, Jens, MD, DMSc, Holmvang, Lene, MD, DMSc, Clemmensen, Peter, MD, DMSc, Engstrøm, Thomas, MD, PhD, DMSc, Grande, Peer, MD, DMSc, Saunamäki, Kari, MD, DMSc, Jørgensen, Erik, MD

“…Abstract Background Short-term mortality has been studied thoroughly in patients undergoing primary percutaneous coronary intervention (PCI), whereas long-term…”
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Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial by Kølle, Stig-Frederik Trojahn, MD, Fischer-Nielsen, Anne, PhD, Mathiasen, Anders Bruun, MD, Elberg, Jens Jørgen, MD, Oliveri, Roberto S, PhD, Glovinski, Peter V, MD, Kastrup, Jens, Prof, Kirchhoff, Maria, DMSc, Rasmussen, Bo Sonnich, MD, Talman, Maj-Lis Møller, MD, Thomsen, Carsten, Prof, Dickmeiss, Ebbe, DMSc, Drzewiecki, Krzysztof Tadeusz, Prof

“…Summary Background Autologous fat grafting is increasingly used in reconstructive surgery. However, resorption rates ranging from 25% to 80% have been…”
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The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: the BAMI trial by Mathur, Anthony, Fernández-Avilés, Francisco, Bartunek, Jozef, Belmans, Ann, Crea, Filippo, Dowlut, Sheik, Galiñanes, Manuel, Good, Marie-Claire, Hartikainen, Juha, Hauskeller, Christine, Janssens, Stefan, Kala, Petr, Kastrup, Jens, Martin, John, Menasché, Philippe, Sanz-Ruiz, Ricardo, Ylä-Herttuala, Seppo, Zeiher, Andreas

“…Abstract Aims  Bone marrow-derived mononuclear cell (BM-MNC) therapy may improve myocardial recovery in patients following acute myocardial infarction (AMI),…”
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Increased Paracrine Immunomodulatory Potential of Mesenchymal Stromal Cells in Three-Dimensional Culture by Follin, Bjarke, Juhl, Morten, Cohen, Smadar, Perdersen, Anders Elm, Kastrup, Jens, Ekblond, Annette

“…Mesenchymal stromal/stem cells (MSCs) have been investigated extensively through the past years, proving to have great clinical therapeutic potential. In vitro…”
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A randomized double-blind control study of early intra-coronary autologous bone marrow cell infusion in acute myocardial infarction: the REGENERATE-AMI clinical trial by Choudry, Fizzah, Hamshere, Stephen, Saunders, Natalie, Veerapen, Jessry, Bavnbek, Katrine, Knight, Charles, Pellerin, Denis, Locca, Didier, Westwood, Mark, Rakhit, Roby, Crake, Tom, Kastrup, Jens, Parmar, Mahesh, Agrawal, Samir, Jones, Daniel, Martin, John, Mathur, Anthony

“…Clinical trials suggest that intracoronary delivery of autologous bone marrow-derived cells (BMCs) 1-7 days post-acute myocardial infarction (AMI) may improve…”
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Cardiac Magnetic Resonance Imaging used for Evaluation of Adipose-Derived Stromal Cell Therapy in Patients with Chronic Ischemic Heart Disease by Qayyum, Abbas Ali, Mathiasen, Anders Bruun, Mygind, Naja Dam, Vejlstrup, Niels Groove, Kastrup, Jens

“…Adipose-derived stromal cell (ASC) therapy is currently investigated as a new treatment option for patients with ischemic heart disease (IHD). The aim of this…”
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Coronary Microvascular Function and Cardiovascular Risk Factors in Women With Angina Pectoris and No Obstructive Coronary Artery Disease: The iPOWER Study by Mygind, Naja Dam, Michelsen, Marie Mide, Pena, Adam, Frestad, Daria, Dose, Nynne, Aziz, Ahmed, Faber, Rebekka, Høst, Nis, Gustafsson, Ida, Hansen, Peter Riis, Hansen, Henrik Steen, Bairey Merz, C. Noel, Kastrup, Jens, Prescott, Eva

“…Background The majority of women with angina‐like chest pain have no obstructive coronary artery disease when evaluated with coronary angiography. Coronary…”
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Adipose-derived regenerative cells in patients with ischemic cardiomyopathy: The PRECISE Trial by Perin, Emerson C., MD, PhD, Sanz-Ruiz, Ricardo, MD, Sánchez, Pedro L., MD, PhD, Lasso, José, MD, PhD, Pérez-Cano, Rosa, MD, PhD, Alonso-Farto, Juan C., MD, PhD, Pérez-David, Esther, MD, PhD, Fernández-Santos, Maria Eugenia, PhD, Serruys, Patrick W., MD, PhD, Duckers, Henrick J., MD, PhD, Kastrup, Jens, MD, Chamuleau, Steven, MD, PhD, Zheng, Yi, MD, Silva, Guilherme V., MD, Willerson, James T., MD, PhD, Fernández-Avilés, Francisco, MD, PhD

“…Aims Adipose-derived regenerative cells (ADRCs) can be isolated from liposuction aspirates and prepared as fresh cells for immediate administration in cell…”
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Optimizing an immunomodulatory potency assay for Mesenchymal Stromal Cell by Hansen, Stine Bangsgaard, Højgaard, Lisbeth Drozd, Kastrup, Jens, Ekblond, Annette, Follin, Bjarke, Juhl, Morten

“…The expeditious progress of Mesenchymal Stromal Cells (MSC) for therapeutic intervention calls for means to compare differences in potency of cell products…”
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Inflammation, non-endothelial dependent coronary microvascular function and diastolic function—Are they linked? by Suhrs, Hannah E, Schroder, Jakob, Bové, Kira B, Mygind, Naja D, Frestad, Daria, Michelsen, Marie M, Lange, Theis, Gustafsson, Ida, Kastrup, Jens, Prescott, Eva

“…Purpose Systemic inflammation and coronary microvascular dysfunction (CMD) may be causal drivers of heart failure with preserved ejection fraction (HFpEF). We…”
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Development of large-scale manufacturing of adipose-derived stromal cells for clinical applications using bioreactors and human platelet lysate by Haack-Sørensen, Mandana, Juhl, Morten, Follin, Bjarke, Harary Søndergaard, Rebekka, Kirchhoff, Maria, Kastrup, Jens, Ekblond, Annette

“…In vitro expanded adipose-derived stromal cells (ASCs) are a useful resource for tissue regeneration. Translation of small-scale autologous cell production…”
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Autologous adipose-derived stromal cell treatment for patients with refractory angina (MyStromalCell Trial): 3-years follow-up results by Qayyum, Abbas Ali, Mathiasen, Anders Bruun, Helqvist, Steffen, Jørgensen, Erik, Haack-Sørensen, Mandana, Ekblond, Annette, Kastrup, Jens

“…Stem cell therapy is investigated as a treatment option for patients with ischemic heart disease. In this study, long-term safety and efficacy of autologous…”
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Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non‐treatable Cardiac diseasE (SCIENCE) by Paitazoglou, Christina, Bergmann, Martin W., Vrtovec, Bojan, Chamuleau, Steven A.J., van Klarenbosch, Bas, Wojakowski, Wojtek, Michalewska‐Włudarczyk, Aleksandra, Gyöngyösi, Mariann, Ekblond, Annette, Haack‐Sørensen, Mandana, Jaquet, Kai, Vrangbæk, Karsten, Kastrup, Jens, Ciosek, Joanna, Dworowy, Sebastian, Jadczyk, Tomasz, Kozłowski, Michal, Nadrowski, Pawel, Sagalski, Ronja, Schlegel, Esther, Schmidt, Annette, Sikora, Anna, Skiba, Dorota, Traxler, Denise, Qayyum, Abbas Ali, Mathiasen, Anders B.

“…Aims Ischaemic heart failure (IHF) patients have a poor prognosis even with current guideline‐derived therapy. Intramyocardial injections of autologous or…”
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Plasma Small Extracellular Vesicle Cardiac miRNA Expression in Patients with Ischemic Heart Failure, Randomized to Percutaneous Intramyocardial Treatment of Adipose Derived Stem Cells or Placebo: Subanalysis of the SCIENCE Study by Traxler, Denise, Dannenberg, Varius, Zlabinger, Katrin, Gugerell, Alfred, Mester-Tonczar, Julia, Lukovic, Dominika, Spannbauer, Andreas, Hasimbegovic, Ena, Kastrup, Jens, Gyöngyösi, Mariann

“…Small extracellular vesicles (EVs) and their cargo are an important component of cell-to-cell communication in cardiac disease. Allogeneic adipose derived stem…”
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GMP Compliant Production of a Cryopreserved Adipose-Derived Stromal Cell Product for Feasible and Allogeneic Clinical Use by Haack-Sørensen, Mandana, Johansen, Ellen Mønsted, Højgaard, Lisbeth Drozd, Kastrup, Jens, Ekblond, Annette

“…The emerging field of advanced therapy medicinal products (ATMP) holds promise of treating a variety of diseases. Adipose-derived stromal cells (ASCs) are…”
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Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in human cardiovascular disease by Håkansson, Kjell E J, Goossens, Eveline A C, Trompet, Stella, van Ingen, Eva, de Vries, Margreet R, van der Kwast, Reginald V C T, Ripa, Rasmus S, Kastrup, Jens, Hohensinner, Philipp J, Kaun, Christoph, Wojta, Johann, Böhringer, Stefan, Le Cessie, Saskia, Jukema, J Wouter, Quax, Paul H A, Nossent, A Yaël

“…Abstract Aims We have shown that 14q32 microRNAs are highly involved in vascular remodelling and cardiovascular disease. However, the 14q32 locus also encodes…”
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Culture expansion of adipose derived stromal cells. A closed automated Quantum Cell Expansion System compared with manual flask-based culture by Haack-Sørensen, Mandana, Follin, Bjarke, Juhl, Morten, Brorsen, Sonja K, Søndergaard, Rebekka H, Kastrup, Jens, Ekblond, Annette

“…Adipose derived stromal cells (ASCs) are a rich and convenient source of cells for clinical regenerative therapeutic approaches. However, applications of ASCs…”
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Investigating the paracrine and juxtacrine abilities of adipose-derived stromal cells in angiogenesis triple cell co-cultures by Harary Søndergaard, Rebekka, Drozd Højgaard, Lisbeth, Haack-Sørensen, Mandana, Hoeeg, Cecilie, Mønsted Johansen, Ellen, Follin, Bjarke, Kastrup, Jens, Ekblond, Annette, Juhl, Morten

“…[Display omitted] •ASCs increase initiation of sprouting equally well in paracrine and juxtacrine triple cell co-cultures.•ASCs surpass the effect of VEGF•ASCs…”
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Diagnostic performance of a new ECG algorithm for reducing false positive cases in patients suspected acute coronary syndrome by Fakhri, Yama, Andersson, Hedvig, Gregg, Richard E., Babaeizadeh, Saeed, Kastrup, Jens, Holmvang, Lene, Clemmensen, Peter

“…Early and correct diagnosis of ST-segment elevation myocardial infarction (STEMI) is crucial for providing timely reperfusion therapy. Patients with ischemic…”
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Adipose Tissue-Derived Stromal Cells Induce a Highly Trophic Environment While Reducing Maturation of Monocyte-Derived Dendritic Cells by Kastrup, Jens, Larsen, Jesper, Gad, Monika, Follin, Bjarke, Juhl, Morten, Ekblond, Annette

“…Allogeneic cell-based therapies using adipose tissue-derived stromal cells (ASCs) offer an off-the-shelf alternative to autologous therapy. An underlying…”
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