Search Results - "Kastner, David B."

Hippocampal replay reflects specific past experiences rather than a plan for subsequent choice by Gillespie, Anna K., Astudillo Maya, Daniela A., Denovellis, Eric L., Liu, Daniel F., Kastner, David B., Coulter, Michael E., Roumis, Demetris K., Eden, Uri T., Frank, Loren M.

“…Executing memory-guided behavior requires storage of information about experience and later recall of that information to inform choices. Awake hippocampal…”
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Inferring hidden structure in multilayered neural circuits by Maheswaranathan, Niru, Kastner, David B, Baccus, Stephen A, Ganguli, Surya

“…A central challenge in sensory neuroscience involves understanding how neural circuits shape computations across cascaded cell layers. Here we attempt to…”
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Spatial Segregation of Adaptation and Predictive Sensitization in Retinal Ganglion Cells by Kastner, David B., Baccus, Stephen A.

“…Sensory systems change their sensitivity based on recent stimuli to adjust their response range to the range of inputs and to predict future sensory input…”
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Critical and maximally informative encoding between neural populations in the retina by Kastner, David B., Baccus, Stephen A., Sharpee, Tatyana O.

“…Computation in the brain involves multiple types of neurons, yet the organizing principles for how these neurons work together remain unclear. Information…”
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Synaptic consolidation: from synapses to behavioral modeling by Ziegler, Lorric, Zenke, Friedemann, Kastner, David B, Gerstner, Wulfram

“…Synaptic plasticity, a key process for memory formation, manifests itself across different time scales ranging from a few seconds for plasticity induction up…”
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Robust and replicable measurement for prepulse inhibition of the acoustic startle response by Miller, Eric A., Kastner, David B., Grzybowski, Michael N., Dwinell, Melinda R., Geurts, Aron M., Frank, Loren M.

“…Measuring animal behavior in the context of experimental manipulation is critical for modeling, and understanding neuropsychiatric disease. Prepulse inhibition…”
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Adaptive feature detection from differential processing in parallel retinal pathways by Ozuysal, Yusuf, Kastner, David B, Baccus, Stephen A

“…To transmit information efficiently in a changing environment, the retina adapts to visual contrast by adjusting its gain, latency and mean response…”
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Partial Cone Loss Triggers Synapse-Specific Remodeling and Spatial Receptive Field Rearrangements in a Mature Retinal Circuit by Care, Rachel A., Kastner, David B., De la Huerta, Irina, Pan, Simon, Khoche, Atrey, Della Santina, Luca, Gamlin, Clare, Santo Tomas, Chad, Ngo, Jenita, Chen, Allen, Kuo, Yien-Ming, Ou, Yvonne, Dunn, Felice A.

“…Resilience of neural circuits has been observed in the persistence of function despite neuronal loss. In vision, acuity and sensitivity can be retained after…”
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Structure of Ero1p, Source of Disulfide Bonds for Oxidative Protein Folding in the Cell by Gross, Einav, Kastner, David B, Kaiser, Chris A, Fass, Deborah

“…The flavoenzyme Ero1p produces disulfide bonds for oxidative protein folding in the endoplasmic reticulum. Disulfides generated de novo within Ero1p are…”
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A Model of Synaptic Reconsolidation by Kastner, David B, Schwalger, Tilo, Ziegler, Lorric, Gerstner, Wulfram

“…Reconsolidation of memories has mostly been studied at the behavioral and molecular level. Here, we put forward a simple extension of existing computational…”
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Adaptation of Inhibition Mediates Retinal Sensitization by Kastner, David B., Ozuysal, Yusuf, Panagiotakos, Georgia, Baccus, Stephen A.

“…In response to a changing sensory environment, sensory systems adjust their neural code for a number of purposes, including an enhanced sensitivity for novel…”
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Memory Alone Does Not Account for the Way Rats Learn a Simple Spatial Alternation Task by Kastner, David B, Gillespie, Anna K, Dayan, Peter, Frank, Loren M

“…Animal behavior provides context for understanding disease models and physiology. However, that behavior is often characterized subjectively, creating…”
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Coordinated dynamic encoding in the retina using opposing forms of plasticity by Baccus, Stephen A, Kastner, David B

“…Adaptation helps sensory neurons optimize in a steady environment, but can cause a failure in transmission when the environment changes suddenly. The authors…”
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Interpreting the retinal neural code for natural scenes: From computations to neurons by Maheswaranathan, Niru, McIntosh, Lane T., Tanaka, Hidenori, Grant, Satchel, Kastner, David B., Melander, Joshua B., Nayebi, Aran, Brezovec, Luke E., Wang, Julia H., Ganguli, Surya, Baccus, Stephen A.

“…Understanding the circuit mechanisms of the visual code for natural scenes is a central goal of sensory neuroscience. We show that a three-layer network model…”
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Synchronous inhibitory pathways create both efficiency and diversity in the retina by Manu, Mihai, McIntosh, Lane T, Kastner, David B, Naecker, Benjamin N, Baccus, Stephen A

“…Sensory receptive fields combine features that originate in different neural pathways. Retinal ganglion cell receptive fields compute intensity changes across…”
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Insights from the retina into the diverse and general computations of adaptation, detection, and prediction by Kastner, David B, Baccus, Stephen A

“…Graphical abstract…”
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Mature Retina Compensates Functionally for Partial Loss of Rod Photoreceptors by Care, Rachel A., Anastassov, Ivan A., Kastner, David B., Kuo, Yien-Ming, Della Santina, Luca, Dunn, Felice A.

“…Loss of primary neuronal inputs inevitably strikes every neural circuit. The deafferented circuit could propagate, amplify, or mitigate input loss, thus…”
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Inhibition, but not excitation, recovers from partial cone loss with greater spatiotemporal integration, synapse density, and frequency by Lee, Joo Yeun, Care, Rachel A., Kastner, David B., Della Santina, Luca, Dunn, Felice A.

“…Neural circuits function in the face of changing inputs, either caused by normal variation in stimuli or by cell death. To maintain their ability to perform…”
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Spatial preferences account for inter-animal variability during the continual learning of a dynamic cognitive task by Kastner, David B., Miller, Eric A., Yang, Zhuonan, Roumis, Demetris K., Liu, Daniel F., Frank, Loren M., Dayan, Peter

“…Understanding the complexities of behavior is necessary to interpret neurophysiological data and establish animal models of neuropsychiatric disease. This…”
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How inhibitory neurons increase information transmission under threshold modulation by Hsu, Wei-Mien M., Kastner, David B., Baccus, Stephen A., Sharpee, Tatyana O.

“…Modulation of neuronal thresholds is ubiquitous in the brain. Phenomena such as figure-ground segmentation, motion detection, stimulus anticipation, and shifts…”
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