Search Results - "Kasthuri, Raj S."

Cancer Therapy–Associated Thrombosis by Grover, Steven P., Hisada, Yohei M., Kasthuri, Raj S., Reeves, Brandi N., Mackman, Nigel

“…Patients with cancer have an increased risk of both arterial and venous thrombotic events compared with the general population. Both the site and stage of…”
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Role of Tissue Factor in Cancer by Kasthuri, Raj S, Taubman, Mark B, Mackman, Nigel

“…Tissue factor (TF) is a transmembrane glycoprotein that localizes the coagulation serine protease factor VII/VIIa (FVII/VIIa) to the cell surface. The primary…”
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An international, multicenter study of intravenous bevacizumab for bleeding in hereditary hemorrhagic telangiectasia: the InHIBIT-Bleed study by Al-Samkari, Hanny, Kasthuri, Raj S, Parambil, Joseph G, Albitar, Hasan A, Almodallal, Yahya A, Vázquez, Carolina, Serra, Marcelo M, Dupuis-Girod, Sophie, Wilsen, Craig B, McWilliams, Justin P, Fountain, Evan H, Gossage, James R, Weiss, Clifford R, Latif, Muhammad A, Issachar, Assaf, Mei-Zahav, Meir, Meek, Mary E, Conrad, Miles, Rodriguez-Lopez, Josanna, Kuter, David J, Iyer, Vivek N

“…Hereditary hemorrhagic telangiectasia (HHT, Osler-Weber-Rendu disease) is a rare multisystem vascular disorder causing chronic gastrointestinal bleeding,…”
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Applicability of the Curaçao Criteria for the Diagnosis of Hereditary Hemorrhagic Telangiectasia in the Pediatric Population by Pahl, Kristy S., Choudhury, Arkopal, Wusik, Katie, Hammill, Adrienne, White, Andrew, Henderson, Katharine, Pollak, Jeffrey, Kasthuri, Raj S.

“…To evaluate the accuracy of the clinical Curaçao criteria in the diagnosis of hereditary hemorrhagic telangiectasia (HHT) in children and adolescents. This was…”
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Integration of clinical parameters, genotype and epistaxis severity score to guide treatment for hereditary hemorrhagic telangiectasia associated bleeding by Beckman, Joan D, Li, Quefeng, Hester, Samuel T, Leitner, Ofri, Smith, Karen L, Kasthuri, Raj S

“…Hereditary Hemorrhagic Telangiectasia (HHT) is a rare inherited disorder characterized by development of mucocutaneous telangiectases and visceral organ…”
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Effect of chemotherapy and longitudinal analysis of circulating extracellular vesicle tissue factor activity in patients with pancreatic and colorectal cancer by Kasthuri, Raj S., Hisada, Yohei, Ilich, Anton, Key, Nigel S., Mackman, Nigel

“…We conducted a longitudinal study in patients with pancreatic and colorectal cancer. We determined the effect of chemotherapy on extracellular vesicle tissue…”
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RBC barcoding allows for the study of erythrocyte population dynamics and P. falciparum merozoite invasion by Clark, Martha A, Goheen, Morgan M, Spidale, Nicholas A, Kasthuri, Raj S, Fulford, Anthony, Cerami, Carla

“…Plasmodium falciparum invasion of host erythrocytes is essential for the propagation of the blood stage of malaria infection. Additionally, the brief…”
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Secondary Immune Thrombocytopenia in Metastatic Renal Cell Carcinoma: A Case Report and Discussion of the Literature by Cockrell, Dillon C., Kasthuri, Raj S., Altun, Ersan, Rose, Tracy L., Milowsky, Matthew I.

“…Immune thrombocytopenia (ITP) is a rare paraneoplastic syndrome of solid tumor malignancies. In previously described cases of renal cell carcinoma (RCC)…”
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Anthracycline treatment of the human monocytic leukemia cell line THP-1 increases phosphatidylserine exposure and tissue factor activity by Boles, Jeremiah C, Williams, Julie C, Hollingsworth, Rachel M, Wang, Jian-Guo, Glover, Sam L, Owens, A. Phillip, Barcel, David A, Kasthuri, Raj S, Key, Nigel S, Mackman, Nigel

“…Abstract Introduction Cancer associated thrombosis is a well-recognized phenomenon that results in considerable patient morbidity and mortality. Malignancy…”
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Challenges in diagnosis and management of acquired factor XIII (FXIII) inhibitors by Beckman, Joan D, Kasthuri, Raj S, Wolberg, Alisa S, Ma, Alice D

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Hereditary hemorrhagic telangiectasia (HHT): a practical guide to management by Hammill, Adrienne M, Wusik, Katie, Kasthuri, Raj S

“…Hereditary hemorrhagic telangiectasia (HHT), the second most common inherited bleeding disorder, is associated with the development of malformed blood vessels…”
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Plasma protein profiling: Unique and stable features of individuals by Nelsestuen, Gary L., Zhang, Yan, Martinez, Michael B., Key, Nigel S., Jilma, Bernd, Verneris, Michael, Sinaiko, Alan, Kasthuri, Raj S.

“…Carefully controlled ZipTip extraction of diluted human plasma or serum was combined with MALDI‐TOF‐MS to produce highly reproducible protein profiles…”
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Platelet transfusion for patients with platelet dysfunction: effectiveness, mechanisms, and unanswered questions by Lee, Robert H., Kasthuri, Raj S., Bergmeier, Wolfgang

“…PURPOSE OF REVIEWIn this review, we discuss current clinical guidelines and potential underlying mechanisms regarding platelet transfusion therapy in patients…”
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Host iron status and iron supplementation mediate susceptibility to erythrocytic stage Plasmodium falciparum by Clark, Martha A., Goheen, Morgan M., Fulford, Anthony, Prentice, Andrew M., Elnagheeb, Marwa A., Patel, Jaymin, Fisher, Nancy, Taylor, Steve M., Kasthuri, Raj S., Cerami, Carla

“…Iron deficiency and malaria have similar global distributions, and frequently co-exist in pregnant women and young children. Where both conditions are…”
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Characteristics and outcomes of venous thromboembolism in patients with hereditary hemorrhagic telangiectasia by Chaturvedi, Shruti, Kohli, Rahil, Schaefer, Nicole, Clancy, Marianne, Kasthuri, Raj S.

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Race, rituximab, and relapse in TTP by Chaturvedi, Shruti, Antun, Ana G, Farland, Andrew M, Woods, Ryan, Metjian, Ara, Park, Yara A, de Ridder, Gustaaf, Gibson, Briana, Kasthuri, Raj S, Liles, Darla K, Akwaa, Frank, Clover, Todd, Baumann Kreuziger, Lisa, Sadler, J Evan, Sridharan, Meera, Go, Ronald S, McCrae, Keith R, Upreti, Harsh Vardhan, Liu, Angela, Lim, Ming Y, Gangaraju, Radhika, Zheng, X Long, Raval, Jay S, Masias, Camila, Cataland, Spero R, Johnson, Andrew, Davis, Elizabeth, Evans, Michael D, Mazepa, Marshall A

“…Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by recurring episodes of thrombotic microangiopathy, causing ischemic organ…”
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PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI by Kasthuri, Raj S., Glover, Sam L., Jonas, William, McEachron, Troy, Pawlinski, Rafal, Arepally, Gowthami M., Key, Nigel S., Mackman, Nigel

“…Heparin-induced thrombocytopenia (HIT) is a potentially devastating form of drug-induced thrombocytopenia that occurs in patients receiving heparin for…”
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Pomalidomide for Epistaxis in Hereditary Hemorrhagic Telangiectasia by Al-Samkari, Hanny, Kasthuri, Raj S., Iyer, Vivek N., Pishko, Allyson M., Decker, Jake E., Weiss, Clifford R., Whitehead, Kevin J., Conrad, Miles B., Zumberg, Marc S., Zhou, Jenny Y., Parambil, Joseph, Marsh, Derek, Clancy, Marianne, Bradley, Lauren, Wisniewski, Lisa, Carper, Benjamin A., Thomas, Sonia M., McCrae, Keith R.

“…Patients with HHT received pomalidomide or placebo for 24 weeks. Pomalidomide reduced epistaxis frequency and severity…”
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Emicizumab reduces re‐hospitalization for bleeding in acquired haemophilia A by Chen, Sheh‐Li, Ellsworth, Patrick, Kasthuri, Raj S., Moll, Stephan, Ma, Alice D., Key, Nigel S.

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Therapeutic plasma exchange taper does not decrease exacerbations in immune thrombotic thrombocytopenic purpura patients by Raval, Jay S., Mazepa, Marshall A., Rollins‐Raval, Marian A., Kasthuri, Raj S., Park, Yara A.

“…BACKGROUND Despite rapid and intensive treatments with therapeutic plasma exchange (TPE) and immunosuppression, immune thrombotic thrombocytopenic purpura…”
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